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2-bromo-4-chloro-6-nitro-phenol

CAS No.
15969-10-5
Chemical Name:
2-bromo-4-chloro-6-nitro-phenol
Synonyms
Phloroglucinol Impurity 238;Phenol, 2-broMo-4-chloro-6-nitro-;2-?nitro-?6-?bromo-?4-?chloro-phenol
CBNumber:
CB91466367
Molecular Formula:
C6H3BrClNO3
Molecular Weight:
252.45
MDL Number:
MFCD00024243
MOL File:
15969-10-5.mol
MSDS File:
SDS
Last updated:2026-05-28 04:36:18

2-bromo-4-chloro-6-nitro-phenol Properties

Melting point 125 °C
Boiling point 250.1±35.0 °C(Predicted)
Density 1.974±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Methanol (Slightly)
pka 4.57±0.38(Predicted)
form Solid
color Yellow

SAFETY

Risk and Safety Statements

2-bromo-4-chloro-6-nitro-phenol price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-B684523-500MG 2-Bromo-4-chloro-6-nitrophenol 15969-10-5 500mg $84 2026-06-03 Buy
TRC TRC-B684523-250MG 2-Bromo-4-chloro-6-nitrophenol 15969-10-5 250mg $72 2026-06-03 Buy
TRC TRC-B684523-100MG 2-Bromo-4-chloro-6-nitrophenol 15969-10-5 100mg $65 2026-06-03 Buy
Synthonix B41963 2-Bromo-4-chloro-6-nitrophenol 97% 15969-10-5 250mg $51 2026-05-06 Buy
Synthonix B41963 2-Bromo-4-chloro-6-nitrophenol 97% 15969-10-5 1g $57 2026-05-06 Buy
Product number Packaging Price Buy
TRC-B684523-500MG 500mg $84 Buy
TRC-B684523-250MG 250mg $72 Buy
TRC-B684523-100MG 100mg $65 Buy
B41963 250mg $51 Buy
B41963 1g $57 Buy

2-bromo-4-chloro-6-nitro-phenol Chemical Properties, Uses, Production

Synthesis

4-CHLORO-2-NITROPHENOL

89-64-5

2-bromo-4-chloro-6-nitro-phenol

15969-10-5

Step 1: 4-Chloro-2-nitrophenol (1.0 eq.) was dissolved in acetic acid (0.64 M) and cooled under ice bath conditions. Subsequently, bromine (1.1 eq.) was added slowly and dropwise to the reaction system, keeping the reaction mixture stirred in an ice bath for 3 hours, during which time it was gradually warmed up to room temperature. After completion of the reaction, bromine (0.3 eq.) was added to the system and stirring was continued for 1 hour. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm that the reaction was essentially complete. Subsequently, pre-cooled deionized water was added to the reaction mixture, which immediately produced a yellow suspension. The mixture was stirred vigorously and the precipitate was collected by filtration. The resulting yellow-orange solid was washed sequentially with deionized water and heptane to obtain a yellow powdery product. The product was dried in a high vacuum drying oven for 3 days to give 2-bromo-4-chloro-6-nitrophenol in 76% yield. The product was analyzed by liquid chromatography-mass spectrometry (LC-MS) showing (m/z) [M+H]+=291.9 and retention time (Rt)=1.45 min.

References

[1] Journal of Organic Chemistry, 2018, vol. 83, # 14, p. 7388 - 7397
[2] Patent: US2010/152160, 2010, A1. Location in patent: Page/Page column 111
[3] Patent: WO2013/49605, 2013, A1. Location in patent: Paragraph 0054
[4] Patent: WO2016/38582, 2016, A1. Location in patent: Paragraph 00335
[5] American Chemical Journal, 1904, vol. 32, p. 15

2-bromo-4-chloro-6-nitro-phenol Preparation Products And Raw materials

Global Suppliers ( 81)
Supplier Tel Email Country ProdList Advantage
Jiangsu Vcare PharmaTech Co., Ltd. 025-58741518 13327700685 sales@vcarepharmatech.com China 281 61
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Wuhan ariel chemical Co., LTD. 18986259541 18986259541 sales@3stc.com China 3827 58
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Xinyanhe Pharmatech Co.,Ltd 0519-85252752 15366845260 taihuaren@vip.163.com China 1031 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Hangzhou J&H Chemical Co., Ltd. 0571-87396432 sales@jhechem.com China 14905 59

2-bromo-4-chloro-6-nitro-phenol Spectrum

Phenol, 2-broMo-4-chloro-6-nitro- 2-?nitro-?6-?bromo-?4-?chloro-phenol Phloroglucinol Impurity 238 15969-10-5 C6H3BrClNO3 C6H5BrClNO3