2-bromo-4-chloro-6-nitro-phenol
- CAS No.
- 15969-10-5
- Chemical Name:
- 2-bromo-4-chloro-6-nitro-phenol
- Synonyms
- Phloroglucinol Impurity 238;Phenol, 2-broMo-4-chloro-6-nitro-;2-?nitro-?6-?bromo-?4-?chloro-phenol
- CBNumber:
- CB91466367
- Molecular Formula:
- C6H3BrClNO3
- Molecular Weight:
- 252.45
- MDL Number:
- MFCD00024243
- MOL File:
- 15969-10-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() ![]() GHS05,GHS07,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H317-H318-H410 |
| Precautionary statements | P261-P264-P270-P272-P273-P280-P301+P312+P330-P302+P352-P305+P351+P338+P310-P333+P313-P391-P501 |
2-bromo-4-chloro-6-nitro-phenol price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-B684523-500MG | 2-Bromo-4-chloro-6-nitrophenol | 15969-10-5 | 500mg | $84 | 2026-06-03 | Buy |
| TRC | TRC-B684523-250MG | 2-Bromo-4-chloro-6-nitrophenol | 15969-10-5 | 250mg | $72 | 2026-06-03 | Buy |
| TRC | TRC-B684523-100MG | 2-Bromo-4-chloro-6-nitrophenol | 15969-10-5 | 100mg | $65 | 2026-06-03 | Buy |
| Synthonix | B41963 | 2-Bromo-4-chloro-6-nitrophenol 97% | 15969-10-5 | 250mg | $51 | 2026-05-06 | Buy |
| Synthonix | B41963 | 2-Bromo-4-chloro-6-nitrophenol 97% | 15969-10-5 | 1g | $57 | 2026-05-06 | Buy |
2-bromo-4-chloro-6-nitro-phenol Chemical Properties, Uses, Production
Synthesis
89-64-5
15969-10-5
Step 1: 4-Chloro-2-nitrophenol (1.0 eq.) was dissolved in acetic acid (0.64 M) and cooled under ice bath conditions. Subsequently, bromine (1.1 eq.) was added slowly and dropwise to the reaction system, keeping the reaction mixture stirred in an ice bath for 3 hours, during which time it was gradually warmed up to room temperature. After completion of the reaction, bromine (0.3 eq.) was added to the system and stirring was continued for 1 hour. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm that the reaction was essentially complete. Subsequently, pre-cooled deionized water was added to the reaction mixture, which immediately produced a yellow suspension. The mixture was stirred vigorously and the precipitate was collected by filtration. The resulting yellow-orange solid was washed sequentially with deionized water and heptane to obtain a yellow powdery product. The product was dried in a high vacuum drying oven for 3 days to give 2-bromo-4-chloro-6-nitrophenol in 76% yield. The product was analyzed by liquid chromatography-mass spectrometry (LC-MS) showing (m/z) [M+H]+=291.9 and retention time (Rt)=1.45 min.
References
[1] Journal of Organic Chemistry, 2018, vol. 83, # 14, p. 7388 - 7397
[2] Patent: US2010/152160, 2010, A1. Location in patent: Page/Page column 111
[3] Patent: WO2013/49605, 2013, A1. Location in patent: Paragraph 0054
[4] Patent: WO2016/38582, 2016, A1. Location in patent: Paragraph 00335
[5] American Chemical Journal, 1904, vol. 32, p. 15
2-bromo-4-chloro-6-nitro-phenol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Vcare PharmaTech Co., Ltd. | 025-58741518 13327700685 | sales@vcarepharmatech.com | China | 281 | 61 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3827 | 58 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Xinyanhe Pharmatech Co.,Ltd | 0519-85252752 15366845260 | taihuaren@vip.163.com | China | 1031 | 58 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9883 | 50 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |







