ChemicalBook >> CAS DataBase List >>1-benzofuran-3-carboxylic acid

1-benzofuran-3-carboxylic acid

CAS No.
26537-68-8
Chemical Name:
1-benzofuran-3-carboxylic acid
Synonyms
3-Carboxybenzo[b]furan;3-Benzofurancarboxylic acid;1-benzofuran-3-carboxylic acid;Benzo[b]furan-3-carboxylic acid;Benzo[b]furan-3-carboxylicacid97%;Benzo[b]furan-3-carboxylic acid 97%;1-benzofuran-3-carboxylic acid(SALTDATA: FREE);3-Carboxybenzo[b]furan, 1-Benzofuran-3-carboxylic acid
CBNumber:
CB91543086
Molecular Formula:
C9H6O3
Molecular Weight:
162.14
MDL Number:
MFCD01006722
MOL File:
26537-68-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-16 21:18:09

1-benzofuran-3-carboxylic acid Properties

Melting point 162℃
Boiling point 325.6±15.0 °C(Predicted)
Density 1.363±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form solid
pka 3.19±0.10(Predicted)
color White
InChI InChI=1S/C9H6O3/c10-9(11)7-5-12-8-4-2-1-3-6(7)8/h1-5H,(H,10,11)
InChIKey BENJFDPHDCGUAQ-UHFFFAOYSA-N
SMILES O1C2=CC=CC=C2C(C(O)=O)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2932990090

1-benzofuran-3-carboxylic acid price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth BBA53768 Benzofuran-3-carboxylic acid 26537-68-8 2.5g $500 2026-06-04 Buy
Biosynth BBA53768 Benzofuran-3-carboxylic acid 26537-68-8 25g $2812.5 2026-06-04 Buy
Apolloscientific OR16562 Benzo[b]furan-3-carboxylic acid 95% 26537-68-8 250mg $45 2026-06-04 Buy
Apolloscientific OR16562 Benzo[b]furan-3-carboxylic acid 95% 26537-68-8 1g $131 2026-06-04 Buy
Matrix Scientific 308329 Benzofuran-3-carboxylic acid 26537-68-8 1.00g $97 2026-05-19 Buy
Product number Packaging Price Buy
BBA53768 2.5g $500 Buy
BBA53768 25g $2812.5 Buy
OR16562 250mg $45 Buy
OR16562 1g $131 Buy
308329 1.00g $97 Buy

1-benzofuran-3-carboxylic acid Chemical Properties, Uses, Production

Synthesis

3-(Methoxymethylene)-2(3H)-benzofuranone

40800-90-6

1-benzofuran-3-carboxylic acid

26537-68-8

The general procedure for the synthesis of benzofuran-3-carboxylic acid from 3-(methoxymethylenyl)-2(3H)-benzofuranone was as follows: 152 g of o-hydroxyphenylacetic acid was added to a reaction flask, 500 g of acetic anhydride and 250 g of trimethyl orthoformate were added. The temperature of the reaction mixture was raised to 80-100 °C and the temperature was maintained for 6 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to give a yellow solid product. To this solid product, 500 g of methanol was added, stirred until completely dissolved, the temperature of the solution was controlled at 0-10 °C, and 180 g of 30% sodium hydroxide solution was slowly added dropwise. Subsequently, the reaction mixture was heated to 50-60°C and kept at this temperature for 3-6 hours. At the end of the reaction, methanol was recovered by distillation under reduced pressure. To the residue, 300 g of drinking water was added, the temperature of the solution was adjusted to below 30 °C, and 160 g of 30% hydrochloric acid was added slowly and dropwise to adjust the pH to 1-2. The mixture was cooled to 0-10 °C and allowed to stand for 3 hours for decantation. The precipitate was collected by filtration and the solid product was washed with cold water. Finally, the product was dried under vacuum to give 158 g of white solid benzofuran-3-carboxylic acid in 97.5% yield.

References

[1] Patent: CN108239054, 2018, A. Location in patent: Paragraph 0009; 0015; 0016; 0018; 0020; 0022; 0024

1-benzofuran-3-carboxylic acid Preparation Products And Raw materials

1-benzofuran-3-carboxylic acid Suppliers

Global Suppliers ( 84)
Supplier Tel Email Country ProdList Advantage
Huigen Biotech (Shanghai) Co., Ltd. 13761582449; 13761582449 qingqing_claire@126.com China 193 58
Shanghai Synthfine Chemical Co.,Ltd 15921303235 sales@synthfine.com China 994 58
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
CEG Chemical Science&Technology Co., Ltd. Mobile:13665161512 China 1784 58
Shanghai JONLN Reagent Co., Ltd. 400-0066400 13621662912 422131432@qq.com China 9970 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Worldyang Chemical Co.,Ltd. 021-56795766 sales@worldyachem.com China 9475 58
Shanghai CanSpecsci Instrument Co., Ltd. 400-6087598 15021221957 order@canspecsci.com China 2001 56

View Latest Price from 1-benzofuran-3-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-benzofuran-3-carboxylic acid pictures 2026-06-30 1-benzofuran-3-carboxylic acid
26537-68-8
1KG 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
1-benzofuran-3-carboxylic acid pictures 2020-01-10 1-benzofuran-3-carboxylic acid
26537-68-8
$1.00 1g 95-99% 1ton Career Henan Chemical Co
1-benzofuran-3-carboxylic acid 3-Benzofurancarboxylic acid Benzo[b]furan-3-carboxylic acid 97% 1-benzofuran-3-carboxylic acid(SALTDATA: FREE) 3-Carboxybenzo[b]furan 3-Carboxybenzo[b]furan, 1-Benzofuran-3-carboxylic acid Benzo[b]furan-3-carboxylic acid Benzo[b]furan-3-carboxylicacid97% 26537-68-8