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4-(Aminomethyl)tetrahydro-2H-pyran-4-amine

CAS No.
50289-16-2
Chemical Name:
4-(Aminomethyl)tetrahydro-2H-pyran-4-amine
Synonyms
4-(Aminomethyl);4-(aminomethyl)oxan-4-amine;4-(Aminomethyl)tetrahydro-2H-pyran-4-amine;2H-Pyran-4-methanamine, 4-aminotetrahydro-
CBNumber:
CB9161360
Molecular Formula:
C6H14N2O
Molecular Weight:
130.19
MDL Number:
MFCD08234566
MOL File:
50289-16-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:56:09

4-(Aminomethyl)tetrahydro-2H-pyran-4-amine Properties

storage temp. Keep in dark place,Inert atmosphere,Room temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

4-(Aminomethyl)tetrahydro-2H-pyran-4-amine price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00DKYA 4-(Aminomethyl)tetrahydro-2H-pyran-4-amine 95% 50289-16-2 50mg $409 2026-05-28 Buy
aablocks AA00DKYA 4-(Aminomethyl)tetrahydro-2H-pyran-4-amine 95% 50289-16-2 100mg $590 2026-05-28 Buy
aablocks AA00DKYA 4-(Aminomethyl)tetrahydro-2H-pyran-4-amine 95% 50289-16-2 250mg $825 2026-05-28 Buy
aablocks AA00DKYA 4-(Aminomethyl)tetrahydro-2H-pyran-4-amine 95% 50289-16-2 500mg $1277 2026-05-28 Buy
aablocks AA00DKYA 4-(Aminomethyl)tetrahydro-2H-pyran-4-amine 95% 50289-16-2 1g $1625 2026-05-28 Buy
Product number Packaging Price Buy
AA00DKYA 50mg $409 Buy
AA00DKYA 100mg $590 Buy
AA00DKYA 250mg $825 Buy
AA00DKYA 500mg $1277 Buy
AA00DKYA 1g $1625 Buy

4-(Aminomethyl)tetrahydro-2H-pyran-4-amine Chemical Properties, Uses, Production

Synthesis

4-AMINOTETRAHYDRO-2H-PYRAN-4-CARBONITRILE

50289-12-8

4-(AMINOMETHYL)TETRAHYDRO-2H-PYRAN-4-AMINE

50289-16-2

GENERAL STEPS: 4-Aminotetrahydro-2H-pyran-4-carbonitrile (10 g, 80 mmol) was slowly added to a suspension of LiAlH4 (9.1 g, 240 mmol) in methyl tertiary butyl ether (MTBE, 120 mL) at room temperature. The reaction mixture was stirred continuously at 40 °C for 2 hours. Upon completion of the reaction, the reaction was quenched by sequential addition of water (9.1 mL) and 15% aqueous NaOH solution (9.1 mL), followed by water (27.3 mL). After continued stirring for 1 h, the reaction mixture was filtered and the filter cake was washed with MTBE (20 mL x 2). After combining the filtrates, 4-(aminomethyl)tetrahydro-2H-pyran-4-amine (6 g, 46.1 mmol) was obtained by vacuum concentration, and the product could be used in subsequent reactions without further purification.

References

[1] Patent: WO2018/5860, 2018, A1. Location in patent: Page/Page column 172; 197; 198
[2] Patent: WO2018/5863, 2018, A1. Location in patent: Page/Page column 127

4-(Aminomethyl)tetrahydro-2H-pyran-4-amine Preparation Products And Raw materials

4-(Aminomethyl)tetrahydro-2H-pyran-4-amine Suppliers

Global Suppliers ( 11)
Supplier Tel Email Country ProdList Advantage
Hangzhou Milestone Pharmtech Co., Ltd. 0571-82896630 18969958410 sales_hz@milestonepharmtech.com China 4908 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-58851090 13913916777 sales01@aikonchem.com China 15947 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946 1461866103@qq.com China 16103 58
Block Chemical Technology (Shanghai) Co., Ltd. 021-20432219 13918097649 li_jinfei@acblock-lab.com China 10032 58
Shandong Welt Chem. Co.,Ltd. 531-87153728 13805401165 xufeng192@126.com China 5858 58
Yanggu Rongke Trading Co., Ltd 15863541132 18366413387@163.com China 5723 58
Jinan Rongke Pharmaceutical Co., Ltd. 18615606162 18366413387@163.com China 5000 58
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 sales@molcore.com China 49709 58
4-(Aminomethyl) 4-(aminomethyl)oxan-4-amine 2H-Pyran-4-methanamine, 4-aminotetrahydro- 4-(Aminomethyl)tetrahydro-2H-pyran-4-amine 50289-16-2