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5-Methyl-1,3,4-oxadiazol-2(3H)-one

CAS No.
3069-67-8
Chemical Name:
5-Methyl-1,3,4-oxadiazol-2(3H)-one
Synonyms
Methyl oxadiazolidone;2-Methyl-1,3,4-Oxadiazol-5(4H)-One;5-Methyl-1,3,4-oxadiazol-2(3H)-one;1,3,4-Oxadiazol-2(3H)-one, 5-methyl-;5-Methyl-2,3-dihydro-1,3,4-oxadiazol-2-one;2,3-dihydro-5-Methyl-2-oxo-1,3,4-oxadiazole;5-methyl-1,3,4-oxadiazol-2-ol(SALTDATA: FREE)
CBNumber:
CB91871604
Molecular Formula:
C3H4N2O2
Molecular Weight:
100.08
MDL Number:
MFCD07779431
MOL File:
3069-67-8.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:47

5-Methyl-1,3,4-oxadiazol-2(3H)-one Properties

Melting point 112 °C
Boiling point 134 °C(Press: 14 Torr)
Density 1.55±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 6.34±0.70(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
HazardClass  IRRITANT

5-Methyl-1,3,4-oxadiazol-2(3H)-one price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M336270 5-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one 3069-67-8 50mg $45 2021-12-16 Buy
Matrix Scientific 063407 5-Methyl-1,3,4-oxadiazol-2-ol 3069-67-8 100mg $195 2021-12-16 Buy
AK Scientific 9464CN 5-Methyl-1,3,4-oxadiazol-2(3H)-one 3069-67-8 10g $676 2021-12-16 Buy
American Custom Chemicals Corporation CHM0078460 5-METHYL-1,3,4-OXADIAZOL-2(3H)-ONE 95.00% 3069-67-8 0.5G $726 2021-12-16 Buy
American Custom Chemicals Corporation CHM0078460 5-METHYL-1,3,4-OXADIAZOL-2(3H)-ONE 95.00% 3069-67-8 1G $808.5 2021-12-16 Buy
Product number Packaging Price Buy
M336270 50mg $45 Buy
063407 100mg $195 Buy
9464CN 10g $676 Buy
CHM0078460 0.5G $726 Buy
CHM0078460 1G $808.5 Buy

5-Methyl-1,3,4-oxadiazol-2(3H)-one Chemical Properties,Uses,Production

Synthesis

Methyl acetate

79-20-9

Acethydrazide

1068-57-1

5-Methyl-1,3,4-oxadiazol-2(3H)-one

3069-67-8

(2) Preparation of 5-methyl-1,3,4-oxadiazolone: 2000 mL of methyl acetate was added to a 5000 mL three-necked flask and 740 g of acetylhydrazine was added slowly under stirring conditions. The reaction mixture was cooled to below 0 °C, followed by the addition of 1680 g of sodium bicarbonate in batches. The reaction unit was sealed and the phosgene was continuously vented at a flow rate of 15 m3/h. After completion of the reaction, the solvent was removed by distillation and the resulting residue was crystallized at 0 °C. The white crystals were collected by filtration to give 988.2 g of the target product in 99% yield.

References

[1] Patent: CN103724327, 2017, B. Location in patent: Paragraph 0008; 0030; 0032

5-Methyl-1,3,4-oxadiazol-2(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 123)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10406 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29800 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
+86-86-22-87899925 +86-8618522618860 18522618860@163.com China 694 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616 gksales1@gk-bio.com China 9236 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58

View Lastest Price from 5-Methyl-1,3,4-oxadiazol-2(3H)-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Methyl-1,3,4-oxadiazol-2(3H)-one pictures 2023-05-09 5-Methyl-1,3,4-oxadiazol-2(3H)-one
3069-67-8
US $300.00-1300.00 / g 100g 98% 10 Shanghai Qianyi New Material Co., Ltd.
5-Methyl-1,3,4-oxadiazol-2(3H)-one pictures 2021-07-13 5-Methyl-1,3,4-oxadiazol-2(3H)-one
3069-67-8
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
5-Methyl-1,3,4-oxadiazol-2(3H)-one pictures 2021-07-10 5-Methyl-1,3,4-oxadiazol-2(3H)-one
3069-67-8
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

5-Methyl-1,3,4-oxadiazol-2(3H)-one Spectrum

5-Methyl-1,3,4-oxadiazol-2(3H)-one 5-methyl-1,3,4-oxadiazol-2-ol(SALTDATA: FREE) 5-Methyl-2,3-dihydro-1,3,4-oxadiazol-2-one 2,3-dihydro-5-Methyl-2-oxo-1,3,4-oxadiazole Methyl oxadiazolidone 2-Methyl-1,3,4-Oxadiazol-5(4H)-One 1,3,4-Oxadiazol-2(3H)-one, 5-methyl- 3069-67-8 Heterocyclic Building Blocks