Ethyl 3-ethoxy-3-iminopropionate hydrochloride
- CAS No.
- 2318-25-4
- Chemical Name:
- Ethyl 3-ethoxy-3-iminopropionate hydrochloride
- Synonyms
- Ethyl 3-ethoxy-3-iMinopropanoate hydrochloride;AURORA KA-6317;IMINOESTERCHLOROHYDRATE;ETHYL-MONO-IMIDO-MALONATE HCL;Ethyl 3-ethoxy-3-iminopropiona...;Ethyl3-ethoxy-3-iminopropionateHCl;3-ethoxy-3-iminopropionate hydrochL;Ethyl 3-ethoxy-3-imino-propanoate HCl;DIETHYL MALONMONOIMIDATE HYDROCHLORIDE;3-ETHOXY-3-IMINOPROPIONIC ACID ETHYL E
- CBNumber:
- CB9213151
- Molecular Formula:
- C7H13NO3.ClH
- Molecular Weight:
- 195.64
- MDL Number:
- MFCD00051405
- MOL File:
- 2318-25-4.mol
- MSDS File:
- SDS
| Melting point | 111-113 °C (decomp) |
|---|---|
| storage temp. | 2-8°C |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C7H13NO3.ClH/c1-3-10-6(8)5-7(9)11-4-2;/h8H,3-5H2,1-2H3;1H |
| InChIKey | HYMXUYQKXCHWDC-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)CC(OCC)=N.[H]Cl |
| CAS DataBase Reference | 2318-25-4(CAS DataBase Reference) |
| FDA UNII | A8DE3DHG8U |
| EPA Substance Registry System | Ethyl 3-ethoxy-3-iminopropionate hydrochloride (2318-25-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| F | 10-21 |
| TSCA | TSCA listed |
| HS Code | 29252900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| REACH Registrations | Active |
Ethyl 3-ethoxy-3-iminopropionate hydrochloride price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 05563 | Ethyl 3-ethoxy-3-imino-propionate hydrochloride technical, ≥85% | 2318-25-4 | 5G-F | $30 | 2023-06-20 | Buy |
| Sigma-Aldrich | 05563 | Ethyl 3-ethoxy-3-imino-propionate hydrochloride technical, ≥85% | 2318-25-4 | 5G | $30 | 2023-01-07 | Buy |
| Sigma-Aldrich | 05563 | Ethyl 3-ethoxy-3-imino-propionate hydrochloride technical, ≥85% | 2318-25-4 | 25g | $77 | 2023-01-07 | Buy |
| TCI Chemical | E1484 | Ethyl 3-Ethoxy-3-iminopropanoate Hydrochloride | 2318-25-4 | 5G | $30 | 2026-04-30 | Buy |
| TCI Chemical | E1484 | Ethyl 3-Ethoxy-3-iminopropanoate Hydrochloride | 2318-25-4 | 25G | $91 | 2026-04-30 | Buy |
Ethyl 3-ethoxy-3-iminopropionate hydrochloride Chemical Properties, Uses, Production
Chemical Properties
White crystalline powder
Uses
Ethyl 3-ethoxy-3-iminopropionate hydrochloride is an intermediate for dacarbamate and acarmine.
Synthesis
64-17-5
105-56-6
2318-25-4
Ethyl cyanoacetate (30 mL, 281 mmol) was dissolved with anhydrous ethanol (18.1 mL, 278 mmol) in anhydrous ether (28.1 mL) at 0°C and stirred to form a homogeneous solution. Dry hydrogen chloride gas was passed into the solution until saturation. Subsequently, the reaction mixture was warmed up to 22°C with continuous stirring for 20 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure to afford ethyl 3-ethoxy-3-iminopropionate hydrochloride (54.4 g, 99% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 4.73 (q, J = 7.1 Hz, 2H); 4.24 (q, J = 7.2 Hz, 2H); 3.89 (s, 2H); 1.51 (t, J = 7.0 Hz, 3H); 1.30 (t, J = 7.2 Hz, 3H) ppm.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 23, p. 7207 - 7213
[2] Chemical and Pharmaceutical Bulletin, 1985, vol. 33, # 7, p. 3046 - 3049
[3] Heterocycles, 1996, vol. 43, # 9, p. 1981 - 1989
[4] Tetrahedron, 2009, vol. 65, # 4, p. 757 - 764
[5] Patent: WO2006/7700, 2006, A1. Location in patent: Page/Page column 66-67
Ethyl 3-ethoxy-3-iminopropionate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Lingxi Technology Co., Ltd | 022-022-60374912 15822944310 | 2725862453@qq.comqq.com | China | 500 | 58 |
| Henan Ruiyun Chang Industrial Co., LTD | 18539434999 | cnhnlxw@163.com | China | 10 | 58 |
| Nanjing Tianyi Chemical Technology Co., Ltd | 15150528611 | 779881375@qq.com | China | 64 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Latest Price from Ethyl 3-ethoxy-3-iminopropionate hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | Ethyl 3-ethoxy-3-iminopropionate hydrochloride
2318-25-4
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2024-11-26 | Ethyl 3-ethoxy-3-iminopropionatehydrochloride
2318-25-4
|
1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd | ||
 |
2022-01-27 | Ethyl 3-ethoxy-3-iminopropionate, HCl
2318-25-4
|
1KG | 97.2% | 100 tons | Honest Joy Holdings Limited |
-
- Ethyl 3-ethoxy-3-iminopropionate hydrochloride
2318-25-4
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Ethyl 3-ethoxy-3-iminopropionatehydrochloride
2318-25-4
- 98%
- Nanjing Fred Technology Co., Ltd
-
- Ethyl 3-ethoxy-3-iminopropionate, HCl
2318-25-4
- $0.00
- 97.2%
- Honest Joy Holdings Limited
