DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS
- CAS No.
- 396716-14-6
- Chemical Name:
- DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS
- Synonyms
- TACE FRET Substrate I;DABCYL-LAQAVRSSSR-EDANS;TACE FRET SUBSTRATE III;DABCYL-TNF-α-EDANS (-4 to +6);TACE SUBSTRATE III, FLUOROGENIC;ADAM-17 SUBSTRATE II, FLUOROGENIC;ADAM-17 SUBSTRATE III, FLUOROGENIC;DABCYL-TNF-a-EDANS: -4 to +6, human;DABCYL-TNF-α-EDANS (-4 to +6) (human);DABCYL-TNF-ALPHA-EDANS (-4 TO +6) (HUMAN)
- CBNumber:
- CB9215342
- Molecular Formula:
- C70H104N22O18S
- Molecular Weight:
- 1573.78
- MDL Number:
- MFCD00798779
- MOL File:
- 396716-14-6.mol
- MSDS File:
- SDS
| Density | 1.46±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | -15°C |
| solubility |
50% acetic acid: 5mg/mL DMSO: 5mg/mL |
| pka | -0.26±0.40(Predicted) |
| form | lyophilized solid |
| color | red |
| Sequence | {DABCYL}-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-{EDANS} |
| UNSPSC Code | 12352200 |
DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 616403 | TACE Substrate III, Fluorogenic - CAS 396716-14-6 - Calbiochem A fluorescence resonance energy transfer (FRET) peptide substrate for TACE (Km = 19 μM). | 396716-14-6 | 500μG | $410 | 2023-01-07 | Buy |
| Biosynth | SFQ-3764-PI | Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans | 396716-14-6 | 1mg | $387.94 | 2026-06-05 | Buy |
| Biosynth | SFQ-3764-PI | Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans | 396716-14-6 | 5mg | $1550.15 | 2026-06-05 | Buy |
| Biosynth | FD110922 | DABCYL-TNF-alpha-EDANS (-4 to +6) (human) trifluoroacetate salt | 396716-14-6 | 250ug | $622.5 | 2026-06-04 | Buy |
| Biosynth | FD110922 | DABCYL-TNF-alpha-EDANS (-4 to +6) (human) trifluoroacetate salt | 396716-14-6 | 500ug | $830 | 2026-06-04 | Buy |
DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS Chemical Properties, Uses, Production
Uses
DABCYL-TNF-α-EDANS (-4 to +6) (human) is a FRET peptide substrate of tumor necrosis factor convertase (TACE)[1].
Biological Activity
Cell permeable: no', 'Km = 19 μM as a fluorescence resonance energy transfer (FRET) peptide substrate for TACE', 'Primary Target
A fluorescence resonance energy transfer (FRET) peptide substrate for TACE', 'Product does not compete with ATP.', 'Reversible: no
References
[1] Liepinsh E, et al. NMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand binding. J Biol Chem. 2003 Jul 11;278(28):25982-9. DOI:10.1074/jbc.M302734200
DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS Preparation Products And Raw materials
Raw materials
Preparation Products
DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 | Caroline@youngshechem.com | China | 4726 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Nanjing chengqimei Biotechnology Co., Ltd | 19850819832 | 2173594524@qq.com | China | 2638 | 58 |




