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2-Fluoro-5-nitroaniline

2-Fluoro-5-nitroaniline Structure
2-Fluoro-5-nitroaniline structure
CAS No.
369-36-8
Chemical Name:
2-Fluoro-5-nitroaniline
Synonyms
2-Fluoro-5-nitrobenzenamine;uoro-5-nitroaniL;Fluoronitroaniline1;2-Fluoro-5-nitroanil;5-Nitro-2-fluoroaniline;2-FLUORO-5-NITROANILINE;6-fluoro-3-nitroaniline;Aniline, 2-fluoro-5-nitro-;2-Fluoro-5-nitroaniline98%;2-Fluoro-5-nitroaniline>
CBNumber:
CB9226014
Molecular Formula:
C6H5FN2O2
Molecular Weight:
156.11
MDL Number:
MFCD00007652
MOL File:
369-36-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:18:46
Product description Number Pack Size Price
2-Fluoro-5-nitroaniline 98% 155853 25g $89.7
2-Fluoro-5-nitroaniline 98% 155853 100g $281
2-Fluoro-5-nitroaniline >99.0%(GC) F0267 25g $65
2-Fluoro-5-nitroaniline 98% 4655-3-05 500g $360
2-Fluoro-5-nitroaniline ≥99%(GC) 45926 25G $103.5
More product size
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2-Fluoro-5-nitroaniline Properties

Melting point 97-100 °C (lit.)
Boiling point 295.5±20.0 °C(Predicted)
Density 1.3822 (estimate)
Flash point 196 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Crystalline Powder
pka 1.13±0.10(Predicted)
color Ochre-yellow to light brown
Water Solubility Slightly soluble
BRN 2803491
InChI InChI=1S/C6H5FN2O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,8H2
InChIKey KJVBJICWGQIMOZ-UHFFFAOYSA-N
SMILES C1(N)=CC([N+]([O-])=O)=CC=C1F
CAS DataBase Reference 369-36-8(CAS DataBase Reference)
NIST Chemistry Reference 2-Fluoro-5-nitroaniline(369-36-8)
EPA Substance Registry System Benzenamine, 2-fluoro-5-nitro- (369-36-8)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H228-H315-H319-H335
Precautionary statements  P210-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  16-26-36
RIDADR  UN 1325 4.1/PG 2
WGK Germany  3
Hazard Note  Irritant
HazardClass  6.1(b)
PackingGroup  III
HS Code  29214210
Storage Class 4.1B - Flammable solid hazardous materials
Hazard Classifications Eye Irrit. 2
Flam. Sol. 1
Skin Irrit. 2
STOT SE 3
Limited Quantities 1.0 Kg (2.2 lbs)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
2 0

2-Fluoro-5-nitroaniline price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 155853 2-Fluoro-5-nitroaniline 98% 369-36-8 25g $89.7 2026-04-30 Buy
Sigma-Aldrich 155853 2-Fluoro-5-nitroaniline 98% 369-36-8 100g $281 2023-06-20 Buy
TCI Chemical F0267 2-Fluoro-5-nitroaniline >99.0%(GC) 369-36-8 25g $65 2026-04-30 Buy
SynQuest Laboratories 4655-3-05 2-Fluoro-5-nitroaniline 98% 369-36-8 500g $360 2026-05-22 Buy
Chem-Impex 45926 2-Fluoro-5-nitroaniline ≥99%(GC) 369-36-8 25G $103.5 2026-05-19 Buy
Product number Packaging Price Buy
155853 25g $89.7 Buy
155853 100g $281 Buy
F0267 25g $65 Buy
4655-3-05 500g $360 Buy
45926 25G $103.5 Buy

2-Fluoro-5-nitroaniline Chemical Properties,Uses,Production

Chemical Properties

ochre-yellow to light brown crystalline powder

Uses

It is employed as pharmaceutical intermediate.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 6141, 1990 DOI: 10.1016/S0040-4039(00)97008-4

Synthesis

2,4-Dinitrofluorobenzene

70-34-8

2-Fluoro-5-nitroaniline

369-36-8

The general procedure for the synthesis of 2-fluoro-5-nitroaniline from 2,4-dinitrofluorobenzene is as follows: 18.61 g (0.10 mol) of 2,4-dinitrofluorobenzene, 0.5 g of 5% palladium-carbon catalyst, 100 mL of glacial acetic acid, and 100 mL of anhydrous ethanol were added to a 500 mL Parr hydrogenation unit. The device was equipped with a thermocouple and a cooling jacket. During the reaction, the temperature of the reaction mixture was maintained at 20-25°C, the hydrogen pressure was maintained at 370 psi, and the reaction time was 2.5 hours. Upon completion of the reaction, the reaction mixture was poured into 400 mL of water. It was extracted twice with 200 mL of dichloromethane, the organic phases were combined and dried over anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure and the resulting residue was filtered through a silica gel pad and eluted with dichloromethane. The eluate was concentrated again under reduced pressure and the residue was further purified by column chromatography using dichloromethane:heptane (80:20, v/v) as eluent. Finally, the solvent was evaporated under reduced pressure to give 2.75 g of 2-fluoro-5-nitroaniline in 17.6% yield.

References

[1] Patent: US5105012, 1992, A
[2] Recueil des Travaux Chimiques des Pays-Bas, 1916, vol. 35, p. 142
[3] Chem. Zentralbl., 1913, vol. 84, # II, p. 760

2-Fluoro-5-nitroaniline Preparation Products And Raw materials

Raw materials

2,4-Dinitrofluorobenzene Acetic acid Water Ethanol Hydrogen

Preparation Products

N1-(2-FLUORO-5-NITROPHENYL)ACETAMIDE 5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester 2-Bromo-4-fluoronitrobenzene 1-(5-amino-2-fluorophenyl)pyrrolidin-2-one N-{2-fluoro-5-nitrophenyl}-3-methylbenzamide
N-(5-amino-2-fluorophenyl)acetamide(SALTDATA: 0.95HCl 0.8H2O)

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2-Fluoro-5-nitroaniline Suppliers

Global( 291)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-18192627656 1059@dideu.com China 3589 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20123 58
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 52513593@qq.com CHINA 2972 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Nanjing Dolon Biotechnology Co.,Ltd. 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58

View Lastest Price from 2-Fluoro-5-nitroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Fluoro-5-nitroaniline pictures 2026-03-20 2-Fluoro-5-nitroaniline
369-36-8
 US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Fluoro-5-nitroaniline pictures 2025-12-12 2-Fluoro-5-nitroaniline
369-36-8
 US $1.00-4.00 / KG 1KG 99% 200000KG Shaanxi Dideu Medichem Co. Ltd
2-Fluoro-5-nitroaniline pictures 2025-12-01 2-Fluoro-5-nitroaniline
369-36-8
 US $0.00-0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

2-Fluoro-5-nitroaniline Spectrum

2-Fluoro-5-nitroaniline(369-36-8)MS2-Fluoro-5-nitroaniline(369-36-8)1HNMR2-Fluoro-5-nitroaniline(369-36-8)13CNMR2-Fluoro-5-nitroaniline(369-36-8)IR12-Fluoro-5-nitroaniline(369-36-8)IR22-Fluoro-5-nitroaniline(369-36-8)Raman

369-36-8(2-Fluoro-5-nitroaniline)Related Search:

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2-Fluoroaniline 2,4-Dinitrofluorobenzene FDNP-VAL-NH2 1,5-Difluoro-2,4-dinitrobenzene 2,4-DINITRO-5-FLUOROTOLUENE
N1-(2,6-DIFLUORO-3-NITROPHENYL)ACETAMIDE 4-Nitroaniline Fluorine 2-FLUORO-5-NITROPHENYL ISOCYANATE (S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide
2,4-DINITRO-5-FLUOROANILINE 2-FLUORO-4-NITROANILINE 5-FLUORO-2-NITROANILINE

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1-Amino-2-fluoro-5-nitrobenzene Aniline, 2-fluoro-5-nitro- Benzenamine, 2-fluoro-5-nitro- 2-FLUORO-5-NITROANILINE F03860 2-Fluoro-5-nitroaniline Fluoronitroaniline1 2-Fluoro-5-nitroaniline 96% 2-Fluoro-5-nitroaniline98% 2-Fluoro-5-nitrobenzenamine 5-Nitro-2-fluoroaniline 2-Fluoro-5-nitroaniline, 98% 25GR 2-Fluoro-5-nitroaniline, 98% 5GR 2-Fluoro-5-nitroaniline, 97+% 2-Fluoro-5-nitroanil 3-Amino-4-fluoronitrobenzene 6-fluoro-3-nitroaniline 2-Fluoro-5-nitroaniline> uoro-5-nitroaniL 369-36-8 (2-FLUORO-5-NITROANILINE ) 2-Fluoro-5-nitroaniline ISO 9001：2015 REACH 369-36-8 FC6H3NO2NH2 Building Blocks Amines C2 to C6 Nitrogen Compounds Organic Building Blocks Aniline series Amines C2 to C6 Nitrogen Compounds Anilines, Aromatic Amines and Nitro Compounds API intermediates