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4-Hydroxybenzophenone

4-Hydroxybenzophenone structure

CAS No.: 1137-42-4

Chemical Name:: 4-Hydroxybenzophenone

Synonyms: POB;P-HYDROXYBENZOPHENONE;(4-hydroxyphenyl)phenyl-methanon;4-Hydroxydiphenylketone;4',2,4-trimethoxy benzophenone;NSC 1887;ENCL-001;benzoylphenol;Ospemifene INT;P-BENZOYLPHENOL

CBNumber:: CB9237221

Molecular Formula:: C13H10O2

Molecular Weight:: 198.22

MDL Number:: MFCD00002355

MOL File:: 1137-42-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 04:44:35

Product description	Number	Pack Size	Price
4-Hydroxybenzophenone 98%	H20202	25g	$74.7
4-Hydroxybenzophenone 98%	H20202	100g	$253
4-Hydroxybenzophenone for synthesis	8.20661	25g	$55.5
4-Hydroxybenzophenone for synthesis	8.20661	100g	$186
4-Hydroxybenzophenone >98.0%(GC)(T)	H0222	25g	$45
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4-Hydroxybenzophenone Properties

Melting point	132-135 °C(lit.)
Boiling point	260-262°C 42mm
Density	1.1184 (rough estimate)
vapor pressure	0Pa at 20℃
refractive index	1.5954 (estimate)
Flash point	260-262°C/24mm
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Powder
pka	8.14±0.13(Predicted)
color	White to beige to brown
Water Solubility	Insoluble in water.
BRN	777776
InChI	1S/C13H10O2/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,14H
InChIKey	NPFYZDNDJHZQKY-UHFFFAOYSA-N
SMILES	Oc1ccc(cc1)C(=O)c2ccccc2
LogP	1.6 at 35℃
CAS DataBase Reference	1137-42-4(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	04R2LWS0MS
NIST Chemistry Reference	Methanone, (4-hydroxyphenyl)phenyl-(1137-42-4)
EPA Substance Registry System	Methanone, (4-hydroxyphenyl)phenyl- (1137-42-4)
UNSPSC Code	12352115
NACRES	NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS08

Signal word

Warning

Hazard statements

H373-H412

Precautionary statements

P260-P273-P314-P501

target organs

Liver,Kidney

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36/37-24/25-36

WGK Germany

RTECS

PC4959775

Hazard Note

Irritant

TSCA

TSCA listed

HS Code

29145000

Storage Class

11 - Combustible Solids

Hazard Classifications

Aquatic Chronic 3
STOT RE 2

REACH Registrations

Active

NFPA 704

	1
2		0

4-Hydroxybenzophenone price More Price(79)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H20202	4-Hydroxybenzophenone 98%	1137-42-4	25g	$74.7	2026-04-30	Buy
Sigma-Aldrich	H20202	4-Hydroxybenzophenone 98%	1137-42-4	100g	$253	2026-04-30	Buy
Sigma-Aldrich	8.20661	4-Hydroxybenzophenone for synthesis	1137-42-4	25g	$55.5	2026-04-30	Buy
Sigma-Aldrich	8.20661	4-Hydroxybenzophenone for synthesis	1137-42-4	100g	$186	2026-04-30	Buy
TCI Chemical	H0222	4-Hydroxybenzophenone >98.0%(GC)(T)	1137-42-4	25g	$45	2026-04-30	Buy

Product number	Packaging	Price	Buy
H20202	25g	$74.7	Buy
H20202	100g	$253	Buy
8.20661	25g	$55.5	Buy
8.20661	100g	$186	Buy
H0222	25g	$45	Buy

4-Hydroxybenzophenone Chemical Properties,Uses,Production

Chemical Properties

white to beige fine crystalline powder

Uses

Metabolite of benzophenone.

Uses

4-Hydroxybenzophenone is used in the field of organic synthesis. It is used as pharmaceutical intermediate of clomifene citrate.

Definition

ChEBI: 4-Hydroxybenzophenone is a member of benzophenones.

Preparation

Preparation by condensation of benzotrichloride,
with phenol in the presence of aluminium chloride in carbon disulfide at 0° (90%) or in the presence of zinc oxide in a water bath;
with p-bromophenol in 30% sodium hydroxide solution at 80–85° (81%). There is substitution of the bromine atom by the benzoyl group.

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 4674, 1955 DOI: 10.1021/ja01622a074
The Journal of Organic Chemistry, 19, p. 978, 1954 DOI: 10.1021/jo01371a016
Tetrahedron Letters, 31, p. 3943, 1990 DOI: 10.1016/S0040-4039(00)97513-0

Flammability and Explosibility

Not classified

Purification Methods

Dissolve p-benzoylphenol in hot EtOH (charcoal), filter and cool. Alternatively crystallise it once from EtOH/H2O and twice from *benzene [Grunwald J Am Chem Soc 73 4934 1951, Dryland & Sheppard J Chem Soc Perkin Trans 1 125 1986]. [Beilstein 8 IV 1263.]

4-Hydroxybenzophenone synthesis

Synthesis of 4-Hydroxybenzophenone from 4-Hydroxyphenylboronic acid and Benzoyl chloride

4-Hydroxybenzophenone Preparation Products And Raw materials

Raw materials

Aluminum chloride Phenyl benzoate Imidodicarbonic acid, 2-benzoyl-, 1,3-bis(1,1-dimethylethyl) ester 4-BENZYLOXYBENZOPHENONE 4-Methoxybenzophenone

Benzoyl chloride, 4-hydroxy- (9CI) 4-BROMOBENZOPHENONE 4-BENZYLPHENOL 4-Hydroxyphenylboronic acid 4-Chlorobenzophenone

Phenylboronic acid 4-Hydroxybenzaldehyde 4-Cyanophenol Anisole

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Preparation Products

Clomiphene Citrate 4-[2-(diethylamino)ethoxy]benzophenone alpha-[4-[2-(diethylamino)ethoxy]phenyl]-alpha-phenylphenethyl alcohol 4-Benzoylphenyl Methacrylate 3,4-Dihydroxybenzophenone

4-Hydroxybenzophenone Suppliers

Global( 617)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Junwee Chemical co., Ltd.	+86-571-85808636 +86-13958122542	sales@junweechem.com	China	823	58
SINO HIGH(CHINA)CO.,LTD.	+86-2558392388 +86-13914336446	chang@sinohighchem.com	China	34	58
Ningbo Banco Chemical Technology Co., Ltd.	+86-15827200700	sales@bancochemical.com	China	487	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Dideu Industries Group Limited	+86-86-15536356810 +8617392712697	1022@dideu.com	China	28760	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5225	58
Firsky International Trade (Wuhan) Co., Ltd	+8615387054039	admin@firsky-cn.com	China	427	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3692	58
Shanghai Likang New Materials Co., Limited	+86-16631818819 +86-17736933208	3684455296@qq.com	China	9300	58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD	+86-15350851019; +8615350851019	admin@86-ss.com	China	999	58

Supplier	Advantage
Junwee Chemical co., Ltd.	58
SINO HIGH(CHINA)CO.,LTD.	58
Ningbo Banco Chemical Technology Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Dideu Industries Group Limited	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Firsky International Trade (Wuhan) Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Shanghai Likang New Materials Co., Limited	58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD	58

View Lastest Price from 4-Hydroxybenzophenone manufacturers

Update time	Product	Price	Purity	Supply Ability	Manufacturer
2026-06-28	4-Hydroxybenzophenone 1137-42-4	$66.00-99.00	99%	5000	HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
2026-06-13	4-Hydroxybenzophenone 1137-42-4		99.84%	10g	TargetMol Chemicals Inc.
2026-06-13	4-Hydroxybenzophenone 1137-42-4		99.84%	10g	TargetMol Chemicals Inc.

4-Hydroxybenzophenone
1137-42-4
$66.00-99.00
99%
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

4-Hydroxybenzophenone
1137-42-4
$0.00
99.84%
TargetMol Chemicals Inc.

4-Hydroxybenzophenone
1137-42-4
$0.00
99.84%
TargetMol Chemicals Inc.

4-Hydroxybenzophenone Spectrum

4-Hydroxybenzophenone(1137-42-4)MS 4-Hydroxybenzophenone(1137-42-4)¹HNMR 4-Hydroxybenzophenone(1137-42-4)¹³CNMR 4-Hydroxybenzophenone(1137-42-4)IR1 4-Hydroxybenzophenone(1137-42-4)IR2

1137-42-4(4-Hydroxybenzophenone)Related Search:

Acetaldehyde HYDROXYAPATITE TYPE I Diphenyl ether Phenyl salicylate Glycolic acid

Benzophenone hydrazone Benzophenone PHENYL VALERATE Hydroxy silicone oil 4-Chlorobenzophenone

4-Methoxybenzophenone AKOS BB-9928 PHENYL RESIN 2,3,3',4'-TETRAMETHOXYBENZOPHENONE 3,4-Dihydroxybenzophenone

2,4-Dihydroxybenzophenone 2,6-DIHYDROXYANTHRAQUINONE 2,2'-Dihydroxy-4-methoxybenzophenone

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4-hydroxy-benzophenon 4-Hydroxydiphenylketone 4-Hydroxyphenylphenylketone Benzophenone, 4-hydroxy- benzoylphenol P-BENZOYLPHENOL P-HYDROXYBENZOPHENONE 4-BENZOYLPHENOL 4-HYDROXYBENZOPHENONE (4-HYDROXY-PHENYL)-PHENYL-METHANONE HYDROXYBENZOPHENONE-4 4-Hydroxybenzophenone, 99+% Photoinitiator-4HBP 4-Hydroxybenzophenone, pract. Methanone, (4-hydroxyphenyl)phenyl- 4-HYDROXYBENZOPHENONE=99.0% 4-hydroxybenzophenone (intermediate of toremifene citrate) PARA-BENZOYLPHENOL (4-hydroxy)(phenyl)methanone 4-Hydroxybenzophenone, 98+% 4-Hydroxybenzophenone, 99+% 25GR 1-(4-Hydroxyphenyl)-1-phenylMethanone NSC 1887 p-Hydroxybenzophenonfe (4-Hydroxyphenyl)(phenyl)methanone, 4-Benzoylphenol 4-Hydroxybenzophenone≥ 99% (HPLC) 1-benzoyl-4-hydroxy-benzene 4-Hydroxybenzophenone, (4-Hydroxyphenyl)phenyl-methanone ENCL-001 4-Hydroxybenzophene 4-Hydroxybenzophenone, 99%, for synthesis 4-Hydroxybenzophenone> 4-HYDROXYBENZOPHENONE FOR SYNTHESIS Benzophenone 4-Hydroxybenzophenone organic photoinitiators Ospemifene INT 4-hydroxy benzophenone (PHBP) 4-Hydroxydibenzoyl 4-Hydroxybenzophenone (Standard) (4-hydroxyphenyl)phenyl-methanon 4',2,4-trimethoxy benzophenone POB 1137-42-4 1137-72-4 HOC6H4COC6H5 Building Blocks Organic Building Blocks Ketones KETONE Carbonyl Compounds C7 to C8 Aromatics, Metabolites & Impurities Organic Photoinitiators Benzophenone Polymerization Initiators FINE Chemical & INTERMEDIATES Aromatic Benzophenones & Derivatives (substituted) Aromatics Metabolites & Impurities