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2,2'-Dihydroxy-4-methoxybenzophenone

2,2'-Dihydroxy-4-methoxybenzophenone structure

CAS No.: 131-53-3

Chemical Name:: 2,2'-Dihydroxy-4-methoxybenzophenone

Synonyms: BP-8;DIOXYBENZONE;BENZOPHENONE-8;Cyasorb;uv24;DBPB;UV BP-8;enzophenone-8;uf2;UF 2

CBNumber:: CB5191699

Molecular Formula:: C14H12O4

Molecular Weight:: 244.24

MDL Number:: MFCD00002218

MOL File:: 131-53-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

Product description	Number	Pack Size	Price
2,2′-Dihydroxy-4-methoxybenzophenone 98%	323578	25g	$95
Dioxybenzone United States Pharmacopeia (USP) Reference Standard	1214004	150mg	$210
2,2'-Dihydroxy-4-methoxybenzophenone >98.0%(GC)	D0586	25g	$46
2,2'-Dihydroxy-4-methoxybenzophenone	FD62643	10g	$150
Dioxybenzone 99.57%	CS-4451	500mg	$54
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2,2'-Dihydroxy-4-methoxybenzophenone Properties

Melting point	73-75 °C(lit.)
Boiling point	170-175 °C1 mm Hg(lit.)
Density	1.2379 (rough estimate)
vapor pressure	0-0Pa at 20-25℃
refractive index	1.5389 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	7.11±0.35(Predicted)
color	Off-White to Yellow
Merck	14,3303
Stability	Stable. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions	UV ABSORBER
Cosmetic Ingredient Review (CIR)	2,2'-Dihydroxy-4-methoxybenzophenone (131-53-3)
InChI	1S/C14H12O4/c1-18-9-6-7-11(13(16)8-9)14(17)10-4-2-3-5-12(10)15/h2-8,15-16H,1H3
InChIKey	MEZZCSHVIGVWFI-UHFFFAOYSA-N
SMILES	COc1ccc(c(O)c1)C(=O)c2ccccc2O
LogP	2.33 at 23.5℃
CAS DataBase Reference	131-53-3(CAS DataBase Reference)
EWG's Food Scores	2
FDA UNII	B762XZ551X
NIST Chemistry Reference	Dioxybenzone(131-53-3)
EPA Substance Registry System	Dioxybenzone (131-53-3)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P305+P351+P338
target organs	Respiratory system
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	DJ1049500
TSCA	TSCA listed
HS Code	29145090
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
Hazardous Substances Data	131-53-3(Hazardous Substances Data)
REACH Registrations	Active

2,2'-Dihydroxy-4-methoxybenzophenone price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	323578	2,2′-Dihydroxy-4-methoxybenzophenone 98%	131-53-3	25g	$95	2026-04-30	Buy
Sigma-Aldrich	1214004	Dioxybenzone United States Pharmacopeia (USP) Reference Standard	131-53-3	150mg	$210	2026-04-30	Buy
TCI Chemical	D0586	2,2'-Dihydroxy-4-methoxybenzophenone >98.0%(GC)	131-53-3	25g	$46	2026-04-30	Buy
Biosynth	FD62643	2,2'-Dihydroxy-4-methoxybenzophenone	131-53-3	10g	$150	2026-06-04	Buy
ChemScene	CS-4451	Dioxybenzone 99.57%	131-53-3	500mg	$54	2026-06-04	Buy

Product number	Packaging	Price	Buy
323578	25g	$95	Buy
1214004	150mg	$210	Buy
D0586	25g	$46	Buy
FD62643	10g	$150	Buy
CS-4451	500mg	$54	Buy

2,2'-Dihydroxy-4-methoxybenzophenone Chemical Properties,Uses,Production

Chemical Properties

Light yellow powder. Freezing point 68℃, boiling point 170-175℃(0.133kPa), relative density 1.382(25℃).Solubility at 25℃(g/100g solvent): benzene 46.6, n-hexane 2.3, 95% ethanol 21.4, carbon tetrachloride 22.2, methylethyl ketone 55.3, plasticiser DOP 31.1, insoluble in water.

Uses

benzophenone-8 (dioxybenzone) is an FDA-approved sunscreen chemical with uVA-absorption capabilities. It also can protect product degradation arising from uV-light exposure. It has an approved usage level of 3 percent in the united States.

Application

Dioxybenzone is a compound used in sunscreen formulations to block out UVB and UVA harmful rays. Broad-spectrum sunscreens often contain a number of chemical ingredients that absorb UVA and UVB radiation. Many sunscreens contain UVA-absorbing avobenzone or a benzophenone (such as dioxybenzone, oxybenzone, or sulisobenzone), in addition to UVB-absorbing chemical ingredients (some of which also contribute to UVA protection).

Definition

ChEBI: 2,2'-Dihydroxy-4-methoxybenzophenone is a member of benzophenones.

Preparation

preparation by condensation of salicylic acid and m-methoxyphenol.

General Description

Dioxybenzone, also known as benzophenone-8, is an organic compound and a derivative of benzophenone used commercially in sunscreens. It absorbed UV-B and UV-AII rays. Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3%.

Reactivity Profile

An alcohol and a ketone. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Fire Hazard

Flash point data for 2,2'-Dihydroxy-4-methoxybenzophenone are not available. 2,2'-Dihydroxy-4-methoxybenzophenone is probably combustible.

2,2'-Dihydroxy-4-methoxybenzophenone synthesis

Synthesis of 2,2'-Dihydroxy-4-methoxybenzophenone from 2,2',4-TRIMETHOXYBENZOPHENONE

2,2'-Dihydroxy-4-methoxybenzophenone Preparation Products And Raw materials

Raw materials

Resorcinol Salicylic acid chloride Dimethyl sulfate

Preparation Products

2,2'-Dihydroxy-4-methoxybenzophenone Suppliers

Global( 316)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
QINGDAO JADE NEW MATERIAL TECNOLOGY CO.,LTD	+86-（+86-532）68077006 13658692156	zandrew@jadenmtc.com	China	222	58
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	8737	58
Hebei Yanxi Chemical Co., Ltd.	+86-17531190177	faithe@yan-xi.com	China	5838	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325	sales1@chuanghaibio.com	China	5218	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7240	58
Dalian Richfortune Chemicals Co., Ltd	+86-86-411-84820922 +86-8613904096939	sales@richfortunechem.com	China	305	57
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32998	60
Tianjin Zhongxin Chemtech Co., Ltd.	86-22-66880623 +8618622897568	sales@tjzxchem.com	China	571	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58

Supplier	Advantage
QINGDAO JADE NEW MATERIAL TECNOLOGY CO.,LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Dalian Richfortune Chemicals Co., Ltd	57
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Tianjin Zhongxin Chemtech Co., Ltd.	58
career henan chemical co	58

View Lastest Price from 2,2'-Dihydroxy-4-methoxybenzophenone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-07	2,2'-Dihydroxy-4-Methoxybenzophenone(UV-24) 131-53-3		1KG	99.5%min	1000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2026-07-15	Dioxybenzone 131-53-3	$58.00		99.39%	10g	TargetMol Chemicals Inc.
2026-07-15	Dioxybenzone 131-53-3	$58.00		99.39%	10g	TargetMol Chemicals Inc.

2,2'-Dihydroxy-4-Methoxybenzophenone(UV-24)
131-53-3
99.5%min
WUHAN FORTUNA CHEMICAL CO., LTD

Dioxybenzone
131-53-3
$58.00
99.39%
TargetMol Chemicals Inc.

Dioxybenzone
131-53-3
$58.00
99.39%
TargetMol Chemicals Inc.

2,2'-Dihydroxy-4-methoxybenzophenone Spectrum

2,2'-Dihydroxy-4-methoxybenzophenone(131-53-3)¹HNMR 2,2'-Dihydroxy-4-methoxybenzophenone(131-53-3)¹³CNMR 2,2'-Dihydroxy-4-methoxybenzophenone(131-53-3)IR1 2,2'-Dihydroxy-4-methoxybenzophenone(131-53-3)Raman

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(2-Hydroxy-4-methoxyphenyl)(2-hydroxphenyl)-methadone (UV 24) 2,2''-DIHYDROXY-4-METHOXYBENZOPHENONE / DIOXYBENZONE 2-2'-Dihydroxy-4-methoxy-benzophenone(UV-24) 2,2-Dihydroxy-4-Methoxy Benzophenone (Benzophenone 8) 2'-Dihydroxy-4-Methoxybenzophenone Dioxybenzone (150 mg) 6-benzoyl-3-Methoxycyclohexa-2,4-diene-1,1-diol UV absorber UV-24 UV Absorber 24 (2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-methanon (2-Hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)methanone (2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-Methanone 2,2’-dihydroxy-4-methoxy-benzophenon 2,2'-DIHYDROXY-4-METHOXYBENZOPHENONE, 98 % LABOTEST-BB LT00159976 Advastab 47 advastab47 Benzophenone, 2,2'-dihydroxy-4-methoxy- component of Solaquin Cyasorb UV 24 Cyasorb UV 24 Light Absorber cyasorbuv24 cyasorbuv24lightabsorber Dioxybenzon Methanone, (2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)- Methanone,(2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)- NSC-56769 Spectra-Sorb UV 24 SpectraSorbUV24 spectra-sorbuv24 Spectro-sorb UV 24 UF 2 uf2 UV 24 uv24 Dioxybenxone DIOXYBENZONE,USP UV Absorber BP-8 -Dihydroxy-4-methoxybenzophenone UV BP-8 2,2'-Dihydroxy-4-methoxybenzophenone > BP-8(UV-24) 2,2'-Dihydroxy-4-methoxybenzophenone ISO 9001：2015 REACH UV ABSORBER FOR LENS BP-8 UV24 2,2'-Dihydroxy-4methoxybenzophenone(BP-8) High purity CAS 131-53-3?2,2'-Dihydroxy-4-methoxybenzophenone in stock 2,2'- hydroxy -4- methoxybenzophenone Sinosorb? BP-8 2,2'-dihydroxy-4-methoxybenzophenone Dioxybenzone, 10 mM in DMSO Ultraviolet absorber BP-8 CHLUMIUV BP-8 CBF-A CSDA2 CSDB EFI-A MDR-NF1 2,2＇-Dihydroxy-4-methoxybenzophenone