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2-(4-BROMO-PHENYL)-THIAZOLE

CAS No.
27149-27-5
Chemical Name:
2-(4-BROMO-PHENYL)-THIAZOLE
Synonyms
2-(4-BROMO-PHENYL)-THIAZOLE;Thiazole, 2-(4-bromophenyl)-;2-(4-bromophenyl)-1,3-thiazole
CBNumber:
CB92453515
Molecular Formula:
C9H6BrNS
Molecular Weight:
240.12
MDL Number:
MFCD09997917
MOL File:
27149-27-5.mol
MSDS File:
SDS
Last updated:2026-05-28 05:00:48
Product description Number Pack Size Price
2-(4-Bromophenyl)-1,3-thiazole CBA14927 0.1g $162.25
2-(4-Bromophenyl)-1,3-thiazole CBA14927 0.25g $259.6
2-(4-Bromophenyl)-1,3-thiazole CBA14927 0.5g $389.4
2-(4-Bromophenyl)-1,3-thiazole CBA14927 1g $519.2
2-(4-Bromophenyl)-1,3-thiazole CBA14927 2g $843.7

2-(4-BROMO-PHENYL)-THIAZOLE Properties

Melting point 52-53 °C
Boiling point 324.3±44.0 °C(Predicted)
Density 1.563±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 1.92±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P305+P351+P338

2-(4-BROMO-PHENYL)-THIAZOLE price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth CBA14927 2-(4-Bromophenyl)-1,3-thiazole 27149-27-5 0.1g $162.25 2026-06-04 Buy
Biosynth CBA14927 2-(4-Bromophenyl)-1,3-thiazole 27149-27-5 0.25g $259.6 2026-06-04 Buy
Biosynth CBA14927 2-(4-Bromophenyl)-1,3-thiazole 27149-27-5 0.5g $389.4 2026-06-04 Buy
Biosynth CBA14927 2-(4-Bromophenyl)-1,3-thiazole 27149-27-5 1g $519.2 2026-06-04 Buy
Biosynth CBA14927 2-(4-Bromophenyl)-1,3-thiazole 27149-27-5 2g $843.7 2026-06-04 Buy
Product number Packaging Price Buy
CBA14927 0.1g $162.25 Buy
CBA14927 0.25g $259.6 Buy
CBA14927 0.5g $389.4 Buy
CBA14927 1g $519.2 Buy
CBA14927 2g $843.7 Buy

2-(4-BROMO-PHENYL)-THIAZOLE Chemical Properties,Uses,Production

Synthesis

2-Bromothiazole

3034-53-5

1-Bromo-4-iodobenzene

589-87-7

2-(4-BROMO-PHENYL)-THIAZOLE

27149-27-5

GENERAL STEPS: 2-Bromothiazole (16.4 g) was dissolved in 50 ml of THF under nitrogen protection and cooled in an ice bath. 55 ml of 2M isopropylmagnesium chloride solution in THF was slowly added dropwise while stirring. After the dropwise addition was completed, stirring of the reaction mixture was continued for 1 hour. Subsequently, zinc chloride-tetramethylethylenediamine complex (30.3 g) was added and stirred at room temperature for 1 hour. Next, 1-bromo-4-iodobenzene (28.3 g) and Pd(PPh3)4 (3.5 g) were added, heated to reflux temperature and stirred for 1.5 hours. After completion of the reaction, it was cooled to room temperature. To remove metal ions from the catalyst, about 2 times the molar amount of ethylenediaminetetraacetic acid disodium salt (EDTA-4Na) aqueous solution was added. Subsequently, the organic phase was separated by extraction with toluene and the solvent was removed by distillation under reduced pressure. Finally, the target product 2-(4-bromophenyl)thiazole (18.3 g) was purified by silica gel column chromatography (eluent: toluene/ethyl acetate = 50/1, v/v).

References

[1] Patent: KR2015/138163, 2015, A. Location in patent: Paragraph 0333; 0334

96159-83-0
27149-27-5
Synthesis of 2-(4-BROMO-PHENYL)-THIAZOLE from Thiazole, 2-(4-bromophenyl)-4,5-dihydro-

2-(4-BROMO-PHENYL)-THIAZOLE Preparation Products And Raw materials

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2-(4-BROMO-PHENYL)-THIAZOLE Thiazole, 2-(4-bromophenyl)- 2-(4-bromophenyl)-1,3-thiazole 27149-27-5