5-BROMO INDOLE-7-CARBOXYLIC ACID
- CAS No.
- 860624-90-4
- Chemical Name:
- 5-BROMO INDOLE-7-CARBOXYLIC ACID
- Synonyms
- 5-broMo-1H-indole-7-carboxylic acid;5-BROMO INDOLE-7-CARBOXYLIC ACID;1H-Indole-7-carboxylic acid, 5-bromo-
- CBNumber:
- CB92465002
- Molecular Formula:
- C9H6BrNO2
- Molecular Weight:
- 240.05
- MDL Number:
- MFCD11845481
- MOL File:
- 860624-90-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-1H-indole-7-carboxylic acid 97% | OR930421 | 250mg | $21 |
| 5-Bromo-1H-indole-7-carboxylic acid 97% | OR930421 | 1g | $62 |
| 5-Bromo-1H-indole-7-carboxylic acid | 127980 | 1.00g | $72 |
| 5-Bromo-1H-indole-7-carboxylic acid | 127980 | 5.00g | $294 |
| 5-Bromo-1H-indole-7-carboxylic acid | 127980 | 25.00g | $883 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315-H302+H312+H332 |
| Precautionary statements | P261-P271-P280 |
| HS Code | 2933998090 |
5-BROMO INDOLE-7-CARBOXYLIC ACID price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR930421 | 5-Bromo-1H-indole-7-carboxylic acid 97% | 860624-90-4 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR930421 | 5-Bromo-1H-indole-7-carboxylic acid 97% | 860624-90-4 | 1g | $62 | 2026-06-04 | Buy |
| Matrix Scientific | 127980 | 5-Bromo-1H-indole-7-carboxylic acid | 860624-90-4 | 1.00g | $72 | 2026-05-18 | Buy |
| Matrix Scientific | 127980 | 5-Bromo-1H-indole-7-carboxylic acid | 860624-90-4 | 5.00g | $294 | 2026-05-18 | Buy |
| Matrix Scientific | 127980 | 5-Bromo-1H-indole-7-carboxylic acid | 860624-90-4 | 25.00g | $883 | 2026-05-18 | Buy |
5-BROMO INDOLE-7-CARBOXYLIC ACID Chemical Properties,Uses,Production
Synthesis
860624-89-1
860624-90-4
The general procedure for the synthesis of 5-bromo-1H-indole-7-carboxylic acid from methyl 5-bromoindole-7-carboxylate was as follows: methyl 5-bromo-1H-indole-7-carboxylate (5 g, 19.7 mmol) was dissolved in methanol (200 mL), followed by the addition of an aqueous solution (10 mL) of lithium hydroxide (0.99 g, 41 mmol). The reaction mixture was heated to reflux and kept for 50 hours. Upon completion of the reaction, methanol was removed by distillation under reduced pressure. The residue was acidified by adding 2M aqueous hydrochloric acid solution to the residue, followed by filtration to collect the precipitate precipitated. The resulting solid was dried in a heated vacuum drying oven to give 4.7 g (99% yield) of the target product 5-bromo-1H-indole-7-carboxylic acid as a beige solid. The product was characterized by 1H NMR (400 MHz, DMSO-D6): δ 6.54 (dd, J = 2.0, 3.2 Hz, 1H), 7.42 (t, J = 2.8 Hz, 1H), 7.77 (d, J = 2.0 Hz, 1H), 8.03 (d, J = 1.8 Hz, 1H), 11.27 (s, 1H), 13.1-13.7 (bs, 1H). Mass spectrometry analysis showed m/z of 238/240 (ratio 1:1, [M-1]-) and retention time (Rt) of 3.41 min.
References
[1] Patent: WO2007/62318, 2007, A2. Location in patent: Page/Page column 39
[2] Patent: WO2008/118724, 2008, A1. Location in patent: Page/Page column 70
[3] Patent: US2006/30613, 2006, A1. Location in patent: Page/Page column 22
[4] Patent: WO2006/34317, 2006, A2. Location in patent: Page/Page column 73-74
[5] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 8, p. 2255 - 2258
5-BROMO INDOLE-7-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
5-BROMO INDOLE-7-CARBOXYLIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5971 | 58 |
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| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9695 | 58 |
