O-Desmethyl-N-deschlorobenzoyl Indomethacin
- CAS No.
- 50995-53-4
- Chemical Name:
- O-Desmethyl-N-deschlorobenzoyl Indomethacin
- Synonyms
- Indomethacin Impurity 6;Indomethacin Impurity 6-d3;5-Hydroxy-2-Methyl-1H-indole-3-acetic Acid;O-Desmethyl-N-deschlorobenzoyl Indomethacin;1H-Indole-3-acetic acid, 5-hydroxy-2-methyl-
- CBNumber:
- CB92508923
- Molecular Formula:
- C11H11NO3
- Molecular Weight:
- 205.21
- MDL Number:
- MFCD22057167
- MOL File:
- 50995-53-4.mol
- MSDS File:
- SDS
| Melting point | 181-184°C |
|---|---|
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Light Brown |
| FDA UNII | UYW56F3GVS |
O-Desmethyl-N-deschlorobenzoyl Indomethacin price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 34581 | O-Desmethyl-N-deschlorobenzoyl Indomethacin ≥95% | 50995-53-4 | 1mg | $38 | 2026-04-30 | Buy |
| Cayman Chemical | 34581 | O-Desmethyl-N-deschlorobenzoyl Indomethacin ≥95% | 50995-53-4 | 5mg | $165 | 2026-04-30 | Buy |
| Cayman Chemical | 34581 | O-Desmethyl-N-deschlorobenzoyl Indomethacin ≥95% | 50995-53-4 | 10mg | $291 | 2026-04-30 | Buy |
| Cayman Chemical | 34581 | O-Desmethyl-N-deschlorobenzoyl Indomethacin ≥95% | 50995-53-4 | 25mg | $634 | 2026-04-30 | Buy |
| Usbiological | 271742 | O-Desmethyl-N-deschlorobenzoyl indomethacin | 50995-53-4 | 5mg | $418 | 2026-06-03 | Buy |
O-Desmethyl-N-deschlorobenzoyl Indomethacin Chemical Properties, Uses, Production
Chemical Properties
Light Brown Solid
Uses
O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin. It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 μM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase. It has also been used in the synthesis of prostaglandin D2 (PGD2) receptor antagonists.
Definition
ChEBI: Desmethyldeschlorobenzoyl Indomethacin is a member of indole-3-acetic acids.
References
[1] KAZUHIKO TORISU . Development of a prostaglandin D2 receptor antagonist: discovery of a new chemical lead[J]. European Journal of Medicinal Chemistry, 2005, 40 5: Pages 505-519. DOI:10.1016/j.ejmech.2004.11.011.
[2] M A EVANS. Indomethacin Metabolism in Isolated Neonatal and Fetal Rabbit Hepatocytes[J]. Pediatric Research, 1981, 15 11: 1406-1410. DOI:10.1203/00006450-198111000-00003.
[3] ANDREW G.M. MORGAN . An evaluation of myeloperoxidase-mediated bio-activation of NSAIDs in promyelocytic leukemia (HL-60) cells for potential cytotoxic selectivity[J]. Toxicology letters, 2017, 280: Pages 48-56. DOI:10.1016/j.toxlet.2017.07.894.
[4] KAZUHIKO TORISU . Discovery of new chemical leads for prostaglandin D2 receptor antagonists[J]. Bioorganic & Medicinal Chemistry Letters, 2004, 14 17: Pages 4557-4562. DOI:10.1016/j.bmcl.2004.06.006.
O-Desmethyl-N-deschlorobenzoyl Indomethacin Preparation Products And Raw materials
O-Desmethyl-N-deschlorobenzoyl Indomethacin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Anmike Chemical Co. Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 9988 | 55 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Jinan blalong chemical co. LTD | 2710913286@qq.com | 1513643261@qq.com | China | 14227 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Zerui Biotechnology Co., Ltd. | 021-54580889 18321124657 | 1054713992@qq.com | China | 10598 | 58 |
View Latest Price from O-Desmethyl-N-deschlorobenzoyl Indomethacin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | O-Desmethyl-N-deschlorobenzoyl Indomethacin
50995-53-4
|
$85.00-660.00 | 10g | TargetMol Chemicals Inc. |
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- O-Desmethyl-N-deschlorobenzoyl Indomethacin
50995-53-4
- $85.00-660.00
- TargetMol Chemicals Inc.
