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5-METHOXY-2-METHYL-3-INDOLEACETIC ACID

CAS No.
2882-15-7
Chemical Name:
5-METHOXY-2-METHYL-3-INDOLEACETIC ACID
Synonyms
NSC 97026;5-MeO,2-Me-IAA;VITAS-BB TBB000392;TIMTEC-BB SBB003362;Indomethacin USP RC A;Acemetacin Impurity 3;Indomethacin Impurity 13;Indometacin EP Impurity B;Indomethacin EP Impurity B;De(chlorobenzoyl)indomethacin.
CBNumber:
CB5488768
Molecular Formula:
C12H13NO3
Molecular Weight:
219.24
MDL Number:
MFCD00005618
MOL File:
2882-15-7.mol
MSDS File:
SDS
Last updated:2026-01-13 11:24:56
Product description Number Pack Size Price
Indomethacin Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 50?mg PHR2770 50MG $621.3
5-Methoxy-2-methyl-3-indoleacetic acid 98% 105171 1g $110
5-Methoxy-2-methyl-3-indoleacetic acid 98% 105171 5g $228.2
Indomethacin Related Compound A United States Pharmacopeia (USP) Reference Standard 1417113 25mg $1300
N-DeschlorobenzoylIndomethacin D288845 1g $120
More product size

5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Properties

Melting point 161-163 °C (lit.)
Boiling point 360.05°C (rough estimate)
Density 1.1825 (rough estimate)
refractive index 1.5270 (estimate)
storage temp. 2-8°C
solubility methanol: soluble
pka 4.22±0.30(Predicted)
form Crystalline Powder
color Off-white to light yellow or light beige
InChI 1S/C12H13NO3/c1-7-9(6-12(14)15)10-5-8(16-2)3-4-11(10)13-7/h3-5,13H,6H2,1-2H3,(H,14,15)
InChIKey TXWGINUZLBAKDF-UHFFFAOYSA-N
SMILES COc1ccc2[nH]c(C)c(CC(O)=O)c2c1
CAS DataBase Reference 2882-15-7(CAS DataBase Reference)
FDA UNII KY9AD0AQM0
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  24/25
WGK Germany  3
HS Code  29349990
Storage Class 11 - Combustible Solids
NFPA 704
0
1 0

5-METHOXY-2-METHYL-3-INDOLEACETIC ACID price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2770 Indomethacin Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 50?mg 2882-15-7 50MG $621.3 2025-07-31 Buy
Sigma-Aldrich 105171 5-Methoxy-2-methyl-3-indoleacetic acid 98% 2882-15-7 1g $110 2025-07-31 Buy
Sigma-Aldrich 105171 5-Methoxy-2-methyl-3-indoleacetic acid 98% 2882-15-7 5g $228.2 2025-07-31 Buy
Sigma-Aldrich 1417113 Indomethacin Related Compound A United States Pharmacopeia (USP) Reference Standard 2882-15-7 25mg $1300 2025-07-31 Buy
TRC D288845 N-DeschlorobenzoylIndomethacin 2882-15-7 1g $120 2021-12-16 Buy
Product number Packaging Price Buy
PHR2770 50MG $621.3 Buy
105171 1g $110 Buy
105171 5g $228.2 Buy
1417113 25mg $1300 Buy
D288845 1g $120 Buy

5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Chemical Properties,Uses,Production

Chemical Properties

slightly yellow fine crystalline powder

Uses

A metabolite of Indomethacin.

Uses

  • Reactant for preparation of antimalarial agents
  • Reactant for preparation of ndomethacin analogs as cyclooxygenase and lipoxygenase inhibitors with antiinflammatory activity
  • Reactant for preparation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents
  • Reactant for preparation of histone deacetylase inhibitors
  • Reactant for preparation of 2,N6,5′-substituted adenosine derivatives as ligands for A2B adenosine receptor
  • Reactant for preparation of prostaglandin D2 receptor antagonist

Uses

5-Methoxy-2-methyl-3-indoleacetic acid was used for quantitative determination of indomethacin and its major impurities in suppository and capsule formulations by HPLC. 5-Methoxy-2-methyl-3-indoleacetic acid was used in a study to develop fast, sensitive and simultaneous determination of metabolites of serotonin using liquid chromatography with mass spectrometric detection.

Definition

ChEBI: N-Deschlorobenzoyl indomethacin is a member of indole-3-acetic acids.

General Description

5-Methoxy-2-methyl-3-indoleacetic acid is hydrolysis product of indomethacin.

5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 170)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29735 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13620 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10236 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15082 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58

View Lastest Price from 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-METHOXY-2-METHYL-3-INDOLEACETIC ACID pictures 2019-12-31 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID
2882-15-7
US $1.00 / KG 1KG 98% 100KG Career Henan Chemical Co
5-METHOXY-2-METHYL INDOLE ACETIC ACID Indomethacin impurity 1/5-methoxy-2-methyl-1H-Indole-3-acetic acid Indomethacin EP Impurity B Indometacin Impurit Ⅰ:5-Methoxy-2-Methyl-3-IndoleaceticAcid Indomethacin USP RC A 5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (5-METHOXY-2-METHYL-1H-INDOL-3-YL)-ACETIC ACID 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 5-methoxy-2-methylindol-3-ylacetic acid De(chlorobenzoyl)indomethacin. 5-methoxy-methylindoleacetic acid 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 98% 5-MeO,2-Me-IAA (2-Methyl-5-methoxy-1H-indole-3-yl)acetic acid 5-Methoxy-2-methyl-1H-indole-3-acetic acid N-Deschlorobenzoylindomethacin 5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (5MeO2MeIAA) 5-Methoxy-2-methyl-3-indoleacetic acid,98% TIMTEC-BB SBB003362 VITAS-BB TBB000392 1H-Indole-3-aceticacid, 5-Methoxy-2-Methyl- 5-Methoxy-2-Methyl-3-indoleacetic acid, 98% 1GR 2-Methyl-5-Methoxy-3-indolylacetic Acid N-Des(4-chlorobenzoyl)indoMethacin NSC 97026 IndoMethacin Related CoMpound A Indometacin EP Impurity B N-deschlorobenzyl Indomethacin Acemetacin Impurity 3 Indomethacin Impurity 13 Indomethacin EP Impurity B/ Indomethacin Related Compound A (Indomethacin N-Deschlorobenzoyl Impurity) Indomethacin Related Compound A (2-(5-methoxy-2-methyl-1H-indol-3-yl)acetic acid) (1417113) Acemetacin Impurity 2/Indomethacin EP impurity B 5-Methoxy-2-methyl-3-indolylacetic Acid Indomethacin (Indometacin) EP Impurity B (Indomethacin USP Related Compound A) 2-(5-methoxy-2-methyl-1H-indol-3-yl)acetic acid - [M72478] Indometacin Imp.B (EP): (5-methoxy-2-Methyl-1H-indol-2-yl) acetic acid 2882-15-7 21924 Heterocyclic Building Blocks Indoles Building Blocks Heterocycles Indole Derivatives Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Heterocyclic Compounds Building Blocks Heterocyclic Building Blocks Indoles Indoles and derivatives