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7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine structure

CAS No.: 937046-98-5

Chemical Name:: 7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine

Synonyms: 7-BroMopyrrolo[2,1-f][1,2,4]triazin-4-aMine;7-Bromo-pyrrolo[2,1-f][1,2,4]triazin-4-ylamine;100207;10G/3000 (T);Remdesivir-007;4-Amino-7-bromo-pyrrolo[2...;-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine;7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine;7-Bromopyrrolo[1,2-f][1,2,4]triazin-44-amine;4-AMino-7-broMo-pyrrolo[2,1-f][1,2,4]triazine

CBNumber:: CB92524820

Molecular Formula:: C6H5BrN4

Molecular Weight:: 213.03

MDL Number:: MFCD09033848

MOL File:: 937046-98-5.mol

TDS File:: TDS

Last updated:2026-05-28 05:39:05

Request For Quotation

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine Properties

Density	2.09±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	2.82±0.30(Predicted)
Appearance	Off-white to gray Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B6237	7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine min. 95.0 %	937046-98-5	1G	$62	2026-04-30	Buy
TCI Chemical	B6237	7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine min. 95.0 %	937046-98-5	5G	$246	2026-04-30	Buy
Chem-Impex	44469	7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine ≥95%(GC)	937046-98-5	1G	$88.93	2026-05-19	Buy
Chem-Impex	44469	7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine ≥95%(GC)	937046-98-5	5G	$269.5	2026-05-19	Buy
Synthonix	A1196	4-Amino-7-bromo-pyrrolo[2,1-f][1,2,4]triazine 97.0%	937046-98-5	1g	$16	2026-05-06	Buy

Product number	Packaging	Price	Buy
B6237	1G	$62	Buy
B6237	5G	$246	Buy
44469	1G	$88.93	Buy
44469	5G	$269.5	Buy
A1196	1g	$16	Buy

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine Chemical Properties, Uses, Production

Uses

7-bromopyrrolo[2,1-f][1,2,4]triazin-4-amine is used in preparation of N-Heterocyclic compounds for pharmaceutical use including as anticancer agents and PRMT5 inhibitors.

Synthesis

159326-68-8

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine

937046-98-5

The general procedure for the synthesis of 4-amino-7-bromopyrrolo[2,1-f][1,2,4]triazines from 4-amino pyrrolo[2,1-f][1,2,4]triazines is as follows: a solution of anhydrous DMF (200 mL) containing 4-amino pyrrolo[2,1-f][1,2,4]triazines (21.0 g, 0.157 mol) was stirred and cooled to -20 °C, followed by the batch addition of 1,3-dibromo-5,5-dimethylglycolide (22.4 g, 0.078 mol), the addition process lasted 45 min. After completion of addition, stirring of the reaction mixture was continued for 45 min and the progress of the reaction was monitored by TLC (silica gel plate, GHLF, 5% CH3OH/CH2Cl2). Upon completion of the reaction, the reaction was quenched by the addition of saturated Na2SO3 solution (300 mL), the resulting suspension was stirred, and the solid product was collected by filtration. The filter cake was washed with water and dried by diafiltration. Subsequently, the dried solid was partitioned between ethyl acetate (1 L) and 5% sodium carbonate solution (1 L) to separate the organic and aqueous layers. The organic layer was washed with fresh 5% sodium carbonate solution and dried with magnesium sulfate. All organic phases were combined and filtered through a Magnesol pad and the filtrate was concentrated under vacuum to give the crude product 4-amino-7-bromopyrrolo[2,1-f][1,2,4]triazine (29.9 g, 90% yield). 21.5 g of the crude product was recrystallized in hot ethyl acetate (300 mL, 70 °C) to give a colorless solid (12.3 g) with about 2% of dibrominated byproducts. The structure of the product was confirmed by 1H-NMR (CD3OD) and mass spectrometry (LC/MS, +ESI): 1H-NMR δ 7.84 (s, 1H), 6.95 (d, 1H, J = 4.7 Hz), 6.71 (d, 1H, J = 4.7 Hz), 4.89 (s, 3H, -NH2 + H2O); MS m/z = 213.1 [M+H].

References

[1] Patent: WO2007/56170, 2007, A2. Location in patent: Page/Page column 74-75
[2] Patent: WO2007/64931, 2007, A2. Location in patent: Page/Page column 164
[3] Asian Journal of Chemistry, 2014, vol. 26, # 20, p. 7083 - 7084
[4] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 1, p. 133 - 137

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine synthesis

Synthesis of 7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine from Pyrrolo[1,2-f][1,2,4]triazin-4-amine

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine Preparation Products And Raw materials

Raw materials

4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Pyrrolo[1,2-f][1,2,4]triazin-4-amine tert-butyl 2-cyano-1H-pyrrol-1-ylcarbaMate 1,3-Dibromo-5,5-dimethylhydantoin N,N-Dimethylformamide

Preparation Products

Ethanone, 1-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2-chloro-

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine Suppliers

Global Suppliers ( 184)

Supplier	Tel	Email	Country	ProdList	Advantage
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Shangchem Co., Ltd.	+86-21-68182121		China	881	52
Nanjing Habo Medical Technology Co., Ltd.	13376080562 13376090521	sales@habotech.com	China	724	60
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
skychemical Co.Ltd	021-20958197 20965099	sales@skychemical.com	China	1182	57
Shanghai AmasPharm Co., Ltd.	021-54540637 18621091017	sales@amaspharm.com	China	787	62
AF Biochem Co., Ltd.	+86-028-60911900 13540204019	sales@afbiochem.com	China	479	57
ZhengZhou HuaWen Chemical Co.Ltd	0370-2785118 17550508557	675141927@qq.com	China	3201	55

Supplier	Advantage
Energy Chemical	61
Shangchem Co., Ltd.	52
Nanjing Habo Medical Technology Co., Ltd.	60
Adamas Reagent, Ltd.	59
Accela ChemBio Co.,Ltd.	64
Shanghai Hanhong Scientific Co.,Ltd.	64
skychemical Co.Ltd	57
Shanghai AmasPharm Co., Ltd.	62
AF Biochem Co., Ltd.	57
ZhengZhou HuaWen Chemical Co.Ltd	55

View Latest Price from 7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-16	7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine 937046-98-5		100g	98%HPLC	100 KGS	WUHAN FORTUNA CHEMICAL CO., LTD
2025-06-20	7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine 937046-98-5		1kg	0.99	20tons	Hebei Yanxi Chemical Co., Ltd.
2021-07-09	7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine 937046-98-5	$1000.00	1KG	≥99%	25tons/week	Hebei Xibaijie Biotechnology Co., Ltd.

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine
937046-98-5
98%HPLC
WUHAN FORTUNA CHEMICAL CO., LTD

7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine
937046-98-5
$0.00
0.99
Hebei Yanxi Chemical Co., Ltd.

7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine
937046-98-5
$1000.00
≥99%
Hebei Xibaijie Biotechnology Co., Ltd.

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine Spectrum

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine(937046-98-5)¹HNMR

937046-98-5 (7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine) Related Search:

2-Heptanone, 7-bromo-1,1,1-trifluoro- 7-bromobenzo[b]thiophene-3-carboxylic acid 7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine Carbamic acid,N-(7-bromopyrrolo[2,1-f][1,2,4]triazin-4-yl)-,1,1-dimethylethyl ester Imidodicarbonic acid, 2-(7-bromopyrrolo[2,1-f][1,2,4]triazin-4-yl)-, 1,3-bis(1,1-dimethylethyl) ester

Pyrrolo[2,1-f][1,2,4]triazin-4-amine, 7-bromo-2-methyl-

1of2

7-bromopyrrolo[1,2-f][1,2,4]triazin-4-amine 4-Amino-7-bromo-pyrrolo[2... 4-AMino-7-broMo-pyrrolo[2,1-f][1,2,4]triazine 7-BroMopyrrolo[2,1-f][1,2,4]triazin-4-aMine 1. 4-AMino-7-broMo-pyrrolo[2,1-f][1,2,4]triazine Remdesivir-007 100207 7-Bromo-pyrrolo[2,1-f][1,2,4]triazin-4-ylamine 10G/3000 (T) Pyrrolo[2,1-f][1,2,4]triazin-4-amine, 7-bromo- 7-Bromopyrrolo[1,2-f][1,2,4]triazin-44-amine 4-amino-7-bromopyrrolidine [2,1-f] [1,2,4] triazine 7-bromopyrrolido [2, 1-F] [1,2,4] triazine-4-amine -bromopyrrolo[1,2-f][1,2,4]triazin-4-amine 937046-98-5