ceftaroline fosamil acetate monohydrate
- CAS No.
- 400827-55-6
- Chemical Name:
- ceftaroline fosamil acetate monohydrate
- Synonyms
- TAK 599 acetate H2O;Ceftaroline fosamil (hydrate)(acetate);ceftaroline fosamil acetate monohydrate;Ceftaroline fosamil acetate hydrate - Bio-X ?;4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-(ethoxyimino)[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium acetate hydra;4-[2-[[(6R,7R)-2-Carboxy-7-[[(2Z)-(ethoxyimino)[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium acetate hydrate;Pyridinium, 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-, acetate, hydrate (1:1:1)
- CBNumber:
- CB92534762
- Molecular Formula:
- C22H22N8O8PS4.C2H3O2.H2O
- Molecular Weight:
- 762.76
- MDL Number:
- MOL File:
- 400827-55-6.mol
- MSDS File:
- SDS
| FDA UNII | P9VXV1408Y |
|---|
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H317-H334 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501 |
ceftaroline fosamil acetate monohydrate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FC172973 | Ceftaroline fosamil acetate hydrate | 400827-55-6 | 25mg | $223 | 2026-06-04 | Buy |
| Biosynth | FC172973 | Ceftaroline fosamil acetate hydrate | 400827-55-6 | 50mg | $359 | 2026-06-04 | Buy |
| Biosynth | FC172973 | Ceftaroline fosamil acetate hydrate | 400827-55-6 | 100mg | $670 | 2026-06-04 | Buy |
| Biosynth | FC172973 | Ceftaroline fosamil acetate hydrate | 400827-55-6 | 250mg | $1037.5 | 2026-06-04 | Buy |
| Biosynth | FC172973 | Ceftaroline fosamil acetate hydrate | 400827-55-6 | 500mg | $1595 | 2026-06-04 | Buy |
ceftaroline fosamil acetate monohydrate Chemical Properties, Uses, Production
Uses
Ceftaroline fosamil hydrate is a potent cephalosporin antibiotic. Ceftaroline fosamil hydrateshows broad-spectrum activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae, and common Gram-negative organisms. Ceftaroline fosamil hydrate has anti-infective activity, and can be used for the research of complicated skin and skin structure infections (cSSSIs) and community-acquired bacterial pneumonia (CABP)[1][2][3].
in vivo
Ceftaroline fosamil hydrate(s.c.) shows protective effects against experimental systemic infection caused by S. aureus N133 in mice, with ED50s of 1.60-2.37 mg/kg[1].
Ceftaroline fosamil hydrate (10 mg/kg; s.c.) disappeares rapidly and converts smoothly into T-91825 in blood of rats and monkeys[1].
IC 50
β-lactam
References
[1] Ishikawa T, et, al. TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: synthesis, physicochemical and pharmacological properties. Bioorg Med Chem. 2003 May 29;11(11):2427-37. DOI:10.1016/s0968-0896(03)00126-3
[2] Biek D, et al. Ceftaroline fosamil: a novel broad-spectrum cephalosporin with expanded anti-Gram-positive activity. J Antimicrob Chemother. 2010 Nov;65 Suppl 4:iv9-16. DOI:10.1093/jac/dkq251
[3] Parish D, et al. Ceftaroline fosamil, a cephalosporin derivative for the potential treatment of MRSA infection. Curr Opin Investig Drugs. 2008 Feb;9(2):201-9. PMID:18246523
ceftaroline fosamil acetate monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
ceftaroline fosamil acetate monohydrate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tongling HengYou Biotechnology Co., Ltd. | 021-50426030 13856289449;13124863828 | 2630597085@qq.com | China | 1885 | 55 |
| Shanghai Bocimed Pharmaceutical Co., Ltd. | +86（21）5895-0312 | sales@bocimed.com | China | 51 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| JINAN SHENGQI PHARMACEUTICAL CO., LTD | 0531-88892685 18660160628 | 2153390475@qq.com | China | 140 | 58 |
| Suzhou Ryway Biotech Co., Ltd | 180-1316-0973 | rywaybio@gmail.com | China | 294 | 55 |
| Zhaoqing Wanwei New Material Technology Co., Ltd. | 0755-1328880-4488 13049823633;13068786899;13288804488 | 13288804488@163.com | China | 623 | 58 |
| Shijiazhuang Gantuo Biotechnology Co., Ltd | gantuo02@cngantuo.com | China | 196 | 58 | |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Shanghai Botuo Biotechnology Co., LTD | 16621358918 | botuopharma888@163.com | China | 9192 | 58 |
View Latest Price from ceftaroline fosamil acetate monohydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-06-26 | Ceftaroline Fosamil Acetate
400827-55-6
|
$200.00 | 1kg | 99% | 1000kg/Month | Hebei Mingeng Biotechnology Co., Ltd | |
 |
2023-04-11 | ceftaroline fosamil acetate monohydrate
400827-55-6
|
$100.00 | 10g | 99% | 1000g | Shijiazhuang Gantuo Biotechnology Co., Ltd | |
 |
2019-12-26 | ceftaroline fosamil acetate monohydrate
400827-55-6
|
$1.00 | 1g | ≥98% | Career Henan Chemical Co |
-
- Ceftaroline Fosamil Acetate
400827-55-6
- $200.00
- 99%
- Hebei Mingeng Biotechnology Co., Ltd
-
- ceftaroline fosamil acetate monohydrate
400827-55-6
- $100.00
- 99%
- Shijiazhuang Gantuo Biotechnology Co., Ltd
-
- ceftaroline fosamil acetate monohydrate
400827-55-6
- $1.00
- ≥98%
- Career Henan Chemical Co
