4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE
- CAS No.
- 55496-69-0
- Chemical Name:
- 4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE
- Synonyms
- 4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE;7-methoxy-6-nitro-4-chloroquinazoline;4-chloro-6-nitro-7-methoxyquinazoline;Quinazoline, 4-chloro-7-methoxy-6-nitro-;New 4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE
- CBNumber:
- CB92548884
- Molecular Formula:
- C9H6ClN3O3
- Molecular Weight:
- 239.62
- MDL Number:
- MFCD11869864
- MOL File:
- 55496-69-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Chloro-7-methoxy-6-nitroquinazoline | 145126 | 5.00g | $1647 |
| 4-Chloro-7-methoxy-6-nitroquinazoline | 145126 | 25.00g | $4940 |
| 4-Chloro-7-methoxy-6-nitroquinazoline 97% | C24249 | 100mg | $40 |
| 4-Chloro-7-methoxy-6-nitroquinazoline 97% | C24249 | 250mg | $50 |
| 4-Chloro-7-methoxy-6-nitroquinazoline 97% | C24249 | 1g | $60 |
| More product size | |||
| Boiling point | 424.6±40.0 °C(Predicted) |
|---|---|
| Density | 1.518±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 0.53±0.70(Predicted) |
| Appearance | Light yellow to yellow Solid |
| InChI | InChI=1S/C9H6ClN3O3/c1-16-8-3-6-5(2-7(8)13(14)15)9(10)12-4-11-6/h2-4H,1H3 |
| InChIKey | MJFJWOAETHEGGW-UHFFFAOYSA-N |
| SMILES | N1=C2C(C=C([N+]([O-])=O)C(OC)=C2)=C(Cl)N=C1 |
4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 145126 | 4-Chloro-7-methoxy-6-nitroquinazoline | 55496-69-0 | 5.00g | $1647 | 2026-05-18 | Buy |
| Matrix Scientific | 145126 | 4-Chloro-7-methoxy-6-nitroquinazoline | 55496-69-0 | 25.00g | $4940 | 2026-05-18 | Buy |
| Synthonix | C24249 | 4-Chloro-7-methoxy-6-nitroquinazoline 97% | 55496-69-0 | 100mg | $40 | 2026-05-06 | Buy |
| Synthonix | C24249 | 4-Chloro-7-methoxy-6-nitroquinazoline 97% | 55496-69-0 | 250mg | $50 | 2026-05-06 | Buy |
| Synthonix | C24249 | 4-Chloro-7-methoxy-6-nitroquinazoline 97% | 55496-69-0 | 1g | $60 | 2026-05-06 | Buy |
4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE Chemical Properties,Uses,Production
Synthesis
1012057-47-4
55496-69-0
Step 22d. Synthesis of 4-chloro-7-methoxy-6-nitroquinazoline (Compound 0305): 7-methoxy-6-nitroquinazolin-4(3H)-one (Compound 0304, 3.8 g, 17.2 mmol) was suspended in phosphorus oxychloride (POCl3, 75 mL), and the reaction mixture was heated to reflux and maintained for 4 hours. Upon completion of the reaction, excess POCl3 was removed by distillation under reduced pressure. the residue was dissolved in a mixture of dichloromethane (50 mL) and aqueous sodium bicarbonate (NaHCO3) (50 mL), and the organic layer was separated and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to afford the target product 4-chloro-7-methoxy-6-nitroquinazoline (compound 0305, 3.4 g, 83% yield). The product was characterized by 1H NMR (DMSO-d6): δ 4.05 (s, 3H), 7.44 (s, 1H), 8.27 (s, 1H), 8.53 (s, 1H).
References
[1] Journal of Medicinal Chemistry, 1996, vol. 39, # 1, p. 267 - 276
[2] Patent: WO2008/33747, 2008, A2. Location in patent: Page/Page column 130
[3] Patent: US2009/76022, 2009, A1. Location in patent: Page/Page column 74-75
[4] Journal of Medicinal Chemistry, 2010, vol. 53, # 5, p. 2000 - 2009
[5] Patent: US2009/111772, 2009, A1. Location in patent: Page/Page column 73
4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5838 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 422 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| Xiamen Shindano Biotechnology Co.,ltd | 0592-6266840 15750707980 | sales@chemsdano.com | China | 291 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8827 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
View Lastest Price from 4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-06-20 | 4-Chloro-7-methoxy-6-nitroquinazoline
55496-69-0
|
$50.00 | 1kg | 0.99 | 100000 | Hebei Yanxi Chemical Co., Ltd. | |
 |
2023-10-08 | 4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE
55496-69-0
|
$30.00 | 1KG | 99% | 20T | Firsky International Trade (Wuhan) Co., Ltd | |
 |
2023-07-19 | 4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE
55496-69-0
|
$30.00 | 1KG | 99% | 30 Tons | Wuhan wingroup Pharmaceutical Co., Ltd |
-
- 4-Chloro-7-methoxy-6-nitroquinazoline
55496-69-0
- $50.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- 4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE
55496-69-0
- $30.00
- 99%
- Firsky International Trade (Wuhan) Co., Ltd
-
- 4-CHLORO-7-METHOXY-6-NITROQUINAZOLINE
55496-69-0
- $30.00
- 99%
- Wuhan wingroup Pharmaceutical Co., Ltd
