1,1-Dibromoformaldoxime
- CAS No.
- 74213-24-4
- Chemical Name:
- 1,1-Dibromoformaldoxime
- Synonyms
- hydroxycarbonimidic dibromide;DIBROMOFORMALDOXIME;dibromomethanone oxime;broMonitrile oxide;74213-24-4;1,1-DibromoformaL;1-Dibromoformaldoxime;1,1-DIBROMOFORMALDOXIME;Pyroxasulfone Impurity 2;1,1-Dibromoformaldoxime,95%
- CBNumber:
- CB9261253
- Molecular Formula:
- CHBr2NO
- Molecular Weight:
- 202.83
- MDL Number:
- MFCD06796211
- MOL File:
- 74213-24-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Dibromoformaldoxime | D425300 | 1g | $45 |
| Dibromoformaldoxime | D425300 | 10g | $120 |
| 1,1-Dibromoformaldoxime 95% | 4147-9-00 | 5G | $101 |
| Dibromoformaldoxime 96+% | 069458 | 25g | $130 |
| 1,1-Dibromoformaldoxime | J99808 | 25g | $130 |
| More product size | |||
| Melting point | 65-68 °C |
|---|---|
| Boiling point | 230.0±23.0 °C(Predicted) |
| Density | 2.70±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Chloroform (Very Slightly, Heated), Methanol |
| form | Solid |
| pka | 7.52±0.11(Predicted) |
| color | White to Dark Orange |
| InChI | InChI=1S/CHBr2NO/c2-1(3)4-5/h5H |
| InChIKey | AWBKQZSYNWLCMW-UHFFFAOYSA-N |
| SMILES | C(/Br)(\Br)=N/O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H318-H335 |
| Precautionary statements | P310-P261-P280 |
| HS Code | 2928009090 |
1,1-Dibromoformaldoxime price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D425300 | Dibromoformaldoxime | 74213-24-4 | 1g | $45 | 2021-12-16 | Buy |
| TRC | D425300 | Dibromoformaldoxime | 74213-24-4 | 10g | $120 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4147-9-00 | 1,1-Dibromoformaldoxime 95% | 74213-24-4 | 5G | $101 | 2021-12-16 | Buy |
| Matrix Scientific | 069458 | Dibromoformaldoxime 96+% | 74213-24-4 | 25g | $130 | 2021-12-16 | Buy |
| AK Scientific | J99808 | 1,1-Dibromoformaldoxime | 74213-24-4 | 25g | $130 | 2021-12-16 | Buy |
1,1-Dibromoformaldoxime Chemical Properties,Uses,Production
Uses
Dibromoformaldoxime is a reagent that undergoes cycloaddition with alkynes to prepare substituted 3-bromo-isoxazoles in high yield.
Synthesis Reference(s)
Tetrahedron Letters, 25, p. 387, 1984 DOI: 10.1016/S0040-4039(00)99890-3
Synthesis
298-12-4
74213-24-4
General procedure for the synthesis of 1,1-dibromoformaldehyde oxime from 2-oxoacetic acid: hydroxylamine hydrochloride (10 mmol) was added to a stirred aqueous (50 mL) solution of glyoxalic acid (10 mmol), and the reaction mixture was stirred for 24 hours at room temperature. Subsequently, sodium bicarbonate (20 mmol) was slowly added, followed by dichloromethane (60 mL). Bromine (1 mL) was added dropwise to the well-stirred two-phase mixture at 6 °C for 20 min. After the addition of bromine, stirring of the reaction mixture was continued for 3 hours. Upon completion of the reaction, the organic layer was separated and the aqueous layer was extracted with dichloromethane (50 mL). The organic extracts were combined, dried with magnesium sulfate, filtered and concentrated under reduced pressure. The residue was recrystallized with hexane (50 mL) to give 1.60 g (81% yield) of a white crystal product with a melting point of 65-66 °C (literature value 19: 63-65 °C).
References
[1] Tetrahedron Letters, 2015, vol. 56, # 13, p. 1635 - 1637
[2] EJNMMI Research, 2018, vol. 8,
[3] Angewandte Chemie - International Edition, 2017, vol. 56, # 13, p. 3703 - 3707
[4] Angew. Chem., 2017, vol. 129, # 13, p. 3757 - 3761,5
[5] Patent: WO2010/127978, 2010, A1. Location in patent: Page/Page column 51
1,1-Dibromoformaldoxime Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 938 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
View Lastest Price from 1,1-Dibromoformaldoxime manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-02 | 1,1-Dibromoformaldoxime
74213-24-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-09-02 | 1,1-Dibromoformaldoxime
74213-24-4
|
US $7.00 / KG | 1KG | 99% | JD 657 | Career Henan Chemical Co |
-
- 1,1-Dibromoformaldoxime
74213-24-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1,1-Dibromoformaldoxime
74213-24-4
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
