MGC34647
- CAS No.
- Chemical Name:
- MGC34647
- Synonyms
- IL34;IL-34;C16orf77;MGC34647;IL-34 human;Monoclonal Anti-IL34 antibody produced in mouse
- CBNumber:
- CB92912874
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| Monoclonal Anti-IL34 antibody produced in mouse clone 1D12, ascites fluid | SAB5300136 | 100 μL | $580 |
| IL34 PurifiedbyProteinGaffinitychromatography. | 565642 | 50ug | $509 |
| IL34 PurifiedbyProteinGaffinitychromatography. | 565642 | 100ug | $708 |
| IL34 | 356797 | 48Tests | $588 |
| IL-34 | 472402 | 96Tests | $731 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P304+P340+P312-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| WGK Germany | WGK 1 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Eye Irrit. 2 STOT SE 3 |
MGC34647 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB5300136 | Monoclonal Anti-IL34 antibody produced in mouse clone 1D12, ascites fluid | 100 μL | $580 | 2026-04-30 | Buy | |
| Usbiological | 565642 | IL34 PurifiedbyProteinGaffinitychromatography. | 50ug | $509 | 2026-06-03 | Buy | |
| Usbiological | 565642 | IL34 PurifiedbyProteinGaffinitychromatography. | 100ug | $708 | 2026-06-03 | Buy | |
| Usbiological | 356797 | IL34 | 48Tests | $588 | 2021-12-16 | Buy | |
| Usbiological | 472402 | IL-34 | 96Tests | $731 | 2021-12-16 | Buy |
MGC34647 Chemical Properties,Uses,Production
Uses
IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1. It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. IL-34, like human CSF-1 stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1.
Biological Activity
IL-34 is a homodimeric cytokine th at is expressed in a range of tissues including spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon. Recombinant human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag.
Description
IL34 Human Recombinant produced in CHO cells is a glycosylated homodimeric polypeptide chain containing 228 amino acids and having a total molecular mass of 26kDa.
IL34 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Source
CHO cells
Background
Interleukin 34 (IL34) is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor and is a part of a group of cytokines called interleukins. IL34 increases growth or survival of immune cells known as monocytes. IL34 protein obtains its activity by binding the Colony stimulating factor 1 receptor. Interleukin 34 has also a potential part in viral infection, the adaptive immune response and bone marrow cell proliferation. Furthermore, IL34 plays an important role in innate immunity and in inflammatory processes.
MGC34647 Preparation Products And Raw materials
Raw materials
Preparation Products
MGC34647 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9865 | 58 |
| Wuhan Peptide Core Biotechnology Co., Ltd | 027-65317797 13667154760 | 1096814016@qq.com | China | 10711 | 58 |
| ACROBiosystems | 13121935750 | jiaxin.zhao@acrobiosystems.com | China | 1495 | 58 |
| CUSABIO TECHNOLOGY LLC | 027-87196173 | cusabio@163.com | China | 6066 | 58 |
| Enzo Biochem Inc | Enzo Biochem Inc. 13797054060 | Enzoname@qq.com | China | 6174 | 58 |
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
| Beijing Biosynthesis Biotechnology Co Ltd | 400-9019800 | sales@bioss.com.cn | China | 6102 | 58 |
| Adooq Bioscience LLC | 400-025-6535 | sales@adooq.cn | China | 6215 | 58 |
| ProSpec Tany TechnoGene Ltd | 972-8947-1175 | info@prospecbio.com | China | 6874 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8132 | 58 |
