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DBCO-SE

DBCO-SE Structure
DBCO-SE structure
CAS No.
Chemical Name:
DBCO-SE
Synonyms
DBCO-SE;Dibenzocyclooctyne-N-hydroxysuccinimidyl ester
CBNumber:
CB92985654
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD24386367
MOL File:
Mol file
Last updated:2025-01-27 09:38:02
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DBCO-SE Properties

Melting point 149-157 (decomposition)
storage temp. -20°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
Stability Moisture Sensitive
UNSPSC Code 12352108
NACRES NA.22

DBCO-SE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 761524 Dibenzocyclooctyne-N-hydroxysuccinimidyl ester for Copper-free Click Chemistry 5 mg $95.38 2025-07-31 Buy
Sigma-Aldrich 761524 Dibenzocyclooctyne-N-hydroxysuccinimidyl ester for Copper-free Click Chemistry 50 mg $364 2025-07-31 Buy
Sigma-Aldrich 761524 Dibenzocyclooctyne-N-hydroxysuccinimidyl ester for Copper-free Click Chemistry 5MG $96.1 2023-06-20 Buy
Sigma-Aldrich 761524 Dibenzocyclooctyne-N-hydroxysuccinimidyl ester for Copper-free Click Chemistry 50MG $339 2023-06-20 Buy
Usbiological 445820 DBCO-NHS Ester 1mg $319 2021-12-16 Buy
Product number Packaging Price Buy
761524 5 mg $95.38 Buy
761524 50 mg $364 Buy
761524 5MG $96.1 Buy
761524 50MG $339 Buy
445820 1mg $319 Buy

DBCO-SE Chemical Properties, Uses, Production

Uses

Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:

  • Protein-peptide conjugates
  • Antibody-enzyme or antibody-drug conjugates
  • Protein or peptide-oligonucleotide conjugates
  • Surface modification

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

DBCO-SE Preparation Products And Raw materials

Raw materials

Preparation Products

DBCO-SE Suppliers

Global Suppliers ( 8)
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25030 58
Supplier Advantage
Sigma-Aldrich 80
Shanghai Universal Biotech Co.,Ltd 58

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Dibenzocyclooctyne-N-hydroxysuccinimidyl ester DBCO-SE