ChemicalBook >> CAS DataBase List >>Tenapanor
Tenapanor
- CAS No.
- 1234423-95-0
- Chemical Name:
- Tenapanor
- Synonyms
- AZD1722;CS-2459;RDX5791;RDX 5791;AZD-1722;Ibsrela.;RDX-5791;AZD 1722;Tenapanor;Tinapanuo
- CBNumber:
- CB93038513
- Molecular Formula:
- C50H66Cl4N8O10S2
- Molecular Weight:
- 1145.04
- MDL Number:
- MFCD28386333
- MOL File:
- 1234423-95-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-17 09:03:53
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO : 50 mg/mL (43.67 mM);Water : < 0.1 mg/mL (insoluble) |
| form | Solid |
| color | White to off-white |
| InChIKey | DNHPDWGIXIMXSA-KQPQOZEFNA-N |
| SMILES | ClC1C=C(Cl)C=C2[C@H](C3C=CC=C(S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(C4C=CC=C([C@@H]5CN(C)CC6=C(C=C(Cl)C=C56)Cl)C=4)(=O)=O)C=3)CN(C)CC=12 |&1:7,52,r| |
| FDA UNII | WYD79216A6 |
| ATC code | A06AX08 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H371 |
| Precautionary statements | P260-P264-P270-P309+P311-P405-P501 |
Tenapanor price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-6273 | Tenapanor 99.59% | 1234423-95-0 | 5mg | $97 | 2026-06-04 | Buy |
| ChemScene | CS-6273 | Tenapanor 99.59% | 1234423-95-0 | 10mg | $157 | 2026-06-04 | Buy |
| ChemScene | CS-6273 | Tenapanor 99.59% | 1234423-95-0 | 25mg | $314 | 2026-06-04 | Buy |
| ChemScene | CS-6273 | Tenapanor 99.59% | 1234423-95-0 | 50mg | $498 | 2026-06-04 | Buy |
| ChemScene | CS-6273 | Tenapanor 99.59% | 1234423-95-0 | 100mg | $756 | 2026-06-04 | Buy |
Tenapanor Chemical Properties, Uses, Production
Uses
Tenapanor is a medicine. This drug targets Nsp16 protein may corroborates a promising approach to combat SARS-CoV-2 virus.
in vivo
Tenapanor (0.15, 0.5 mg/kg; p.o.) reduces passive paracellular phosphate absorption in rats[1].
Tenapanor (0.15 mg/kg; p.o.; twice-daily for 11 consecutive days) increases the reduction in urinary phosphorus excretion in rats[2].
| Animal Model: | Rats (intestinal loop model)[1] |
| Dosage: | 0.15, 0.5 mg/kg |
| Administration: | P.o. |
| Result: | Reduced passive paracellular phosphate absorption by reduced urinary phosphate and sodium excretion after the high-phosphate meal and increased sodium and phosphate delivery to the cecum. |
| Animal Model: | 8 weeks, 250 g male Sprague–Dawley rats[2] |
| Dosage: | 0.15 mg/kg in combination with sevelamer (0%, 0.75%, 1.5%, and 3% (wt/wt)) |
| Administration: | Oral gavage; twice-daily for 11 consecutive days |
| Result: | Significantly augmented the reduction in urinary phosphorus excretion. |
Tenapanor Preparation Products And Raw materials
Raw materials
Preparation Products
Tenapanor Suppliers
Global Suppliers ( 89)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Becas pharmatech Ltd. | +86-13912903754 13912903754 | info@becaspharma.com | China | 3963 | 58 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 | sales@sun-shinechem.com | China | 1197 | 64 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| AdooQ Bioscience CHINA | 025-58849295 | info@adooq.cn | China | 2981 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4859 | 55 | |
| Shanghai Biolang biotechnology Co.,Ltd | 17764003753 | 2326587775@qq.com | China | 185 | 55 |
| Shanghai Biolang biotechnology Co.,Ltd | 17764003753 | 2326587775@qq.com | China | 185 | 55 |
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 4988 | 55 |
| Yangzhou QinYuan Pharmaceutical Co., Ltd. | 0514-80939770 13773367191 | yzqyyykj@163.com | China | 253 | 55 |
View Latest Price from Tenapanor manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-17 | Tenapanor
1234423-95-0
|
$31.00-117.00 | 99.85% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2026-06-30 | Tenapanor
1234423-95-0
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
![]() |
2024-10-31 | Tenapanor
1234423-95-0
|
10g | 0.99 | 1KG | Yangzhou Qinyuan Pharmatech Co.,ltd |
Tenapanor
Rovatirelin Hydrate
Tenapanor(free base)
AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; TENAPANOR FREE BASE; IBSRELA.
Ibsrela.
Tenapanor (AZD1722,RDX5791)
CS-2459
AZD1722
AZD-1722
RDX 5791
RDX5791
RDX-5791
AZD 1722
AZD 1722; AZD1722; AZD-1722; RDX5791; RDX 5791; RDX-5791
Tinapanuo
inhibit,Sodium-hydrogen Exchanger,intestinal,hyperphosphatemia,Sodium/hydrogen Exchanger,Inhibitor,orally active,Tenapanor,Na+/H+ Exchanger (NHE),phosphate absorption
3-((S)-6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-((3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide
Ethopabate Impurity 9
(S)-N,N'-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
Tenapanor, 10 mM in DMSO
Intermediate of tenapanor
17-[[[3-[(4S)-6,8-Dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]ethoxy]ethoxy]ethyl]-8-oxo-12,15-dioxa-2,7,9-triazaheptadecanamide (ACI)
1234423-95-0








