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Mal-PEG5-t-butly ester

CAS No.
518044-36-5
Chemical Name:
Mal-PEG5-t-butly ester
Synonyms
Mal-PEG4-Boc;Mal-PEG4-OtBu;Mal-PEG4-COOtBu;MAL-PEG4-CH2CH2COOTBU;Mal-PEG4-t-butyl ester;Mal-PEG5-t-butly ester;MAL-dPEG4-t-butyl ester;Maleimide tetrapolyethylene glycol tert butyl propionate;tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate;1,1-Dimethylethyl 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-4,7,10,13-tetraoxapentadecanoate
CBNumber:
CB93049629
Molecular Formula:
C19H31NO8
Molecular Weight:
401.45
MDL Number:
MFCD22683300
MOL File:
518044-36-5.mol
MSDS File:
SDS
Last updated:2026-05-28 06:27:30

Mal-PEG5-t-butly ester Properties

Boiling point 499.9±40.0 °C(Predicted)
Density 1.156±0.06 g/cm3(Predicted)
storage temp. -20°C, stored under nitrogen
solubility DMSO : 100 mg/mL (249.10 mM; Need ultrasonic)
pka -2.34±0.20(Predicted)
form Oil
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P302+P352
HS Code  3404200000

Mal-PEG5-t-butly ester price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0108097 Mal-PEG4-Boc ≥95% 518044-36-5 100mg $34 2026-06-04 Buy
ChemScene CS-0108097 Mal-PEG4-Boc ≥95% 518044-36-5 250mg $58 2026-06-04 Buy
ChemScene CS-0108097 Mal-PEG4-Boc ≥95% 518044-36-5 500mg $115 2026-06-04 Buy
ChemScene CS-0108097 Mal-PEG4-Boc ≥95% 518044-36-5 1g $213 2026-06-04 Buy
ChemScene CS-0108097 Mal-PEG4-Boc ≥95% 518044-36-5 5g $994 2026-06-04 Buy
Product number Packaging Price Buy
CS-0108097 100mg $34 Buy
CS-0108097 250mg $58 Buy
CS-0108097 500mg $115 Buy
CS-0108097 1g $213 Buy
CS-0108097 5g $994 Buy

Mal-PEG5-t-butly ester Chemical Properties,Uses,Production

Description

Mal-PEG4-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG5-t-butly ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 40)Suppliers
Supplier Tel Email Country ProdList Advantage
Hunan HuaTeng Pharmaceutical Co., Ltd., 400-8592883 15367835770 sales@huatengsci.com China 5869 58
Borenpharm Co., Ltd 027-65563561 sales@borenpharm.com China 1245 55
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-55629727 13323845623 2885676761@qq.com China 9948 58
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28763 58
Zhongshan Resi Biotechnology Co., Ltd. 13715524166 13326948089 resicn@resicn.com China 519 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
Henan Alfachem Co.,Ltd. 0371-55051623 18137891487 3983243027@qq.com China 9965 58
Alpha Biopharmaceuticals Co., Ltd 0411-39042497 sales@alphabiopharm.com China 1951 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Nextpeptide Inc +86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19904 58

View Lastest Price from Mal-PEG5-t-butly ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mal-PEG4-COOtBu pictures 2025-06-07 Mal-PEG4-COOtBu
518044-36-5
1g >98.00% 1g Xian confluore Biological Technology Co., Ltd.
  • Mal-PEG4-COOtBu pictures
  • Mal-PEG4-COOtBu
    518044-36-5
  • $0.00
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.

Mal-PEG5-t-butly ester Spectrum

Mal-PEG4-COOtBu Mal-PEG5-t-butly ester Mal-PEG4-t-butyl ester MAL-dPEG4-t-butyl ester MAL-PEG4-CH2CH2COOTBU Mal-PEG4-OtBu Mal-PEG4-Boc 4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oate Mal-PEG4-CH2CH2COOtBu/4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester Maleimide tetrapolyethylene glycol tert butyl propionate 1,1-Dimethylethyl 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-4,7,10,13-tetraoxapentadecanoate 518044-36-5 C19H31NO8 peg