tert-butyl 4,5-dibromothiophen-2-ylcarbamate
- CAS No.
- 943321-93-5
- Chemical Name:
- tert-butyl 4,5-dibromothiophen-2-ylcarbamate
- Synonyms
- tert-butyl 4,5-dibromothiophen-2-ylcarbamate;1,1-dimethylethyl (4,5-dibromo-2-thienyl)carbamate;Carbamic acid, N-(4,5-dibromo-2-thienyl)-, 1,1-dimethylethyl ester
- CBNumber:
- CB93075367
- Molecular Formula:
- C9H11Br2NO2S
- Molecular Weight:
- 357.06
- MDL Number:
- MFCD25969363
- MOL File:
- 943321-93-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
tert-butyl 4,5-dibromothiophen-2-ylcarbamate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA01FORR | tert-Butyl (4,5-dibromothiophen-2-yl)carbamate 97% | 943321-93-5 | 100mg | $103 | 2026-05-30 | Buy |
| aablocks | AA01FORR | tert-Butyl (4,5-dibromothiophen-2-yl)carbamate 97% | 943321-93-5 | 250mg | $191 | 2026-05-30 | Buy |
| Ambeed | A146780 | tert-Butyl(4,5-dibromothiophen-2-yl)carbamate 97% | 943321-93-5 | 100mg | $67 | 2021-12-16 | Buy |
| BLDpharm | BD758571 | tert-Butyl(4,5-dibromothiophen-2-yl)carbamate 97% | 943321-93-5 | 100mg | $68 | 2021-12-16 | Buy |
| Ambeed | A146780 | tert-Butyl(4,5-dibromothiophen-2-yl)carbamate 97% | 943321-93-5 | 250mg | $134 | 2021-12-16 | Buy |
tert-butyl 4,5-dibromothiophen-2-ylcarbamate Chemical Properties, Uses, Production
Synthesis
6324-10-3
75-65-0
943321-93-5
GENERAL STEPS: To a solution of 4,5-dibromothiophene-2-carboxylic acid (9.8 mmol, 2.8 g) in tert-butanol (20 mL) were sequentially added diphenylphosphoryl azide (DPPA, 12.5 mmol, 2.7 mL) and triethylamine (29 mmol, 4.2 mL). The reaction mixture was heated to 85 °C and stirred for 12 h under nitrogen protection. Upon completion of the reaction, it was cooled to room temperature and subsequently concentrated under reduced pressure to remove the solvent. Purification of the crude product by fast column chromatography (silica gel as stationary phase, hexane/ethyl acetate=10:1 as eluent) afforded tert-butyl (4,5-dibromothiophen-2-yl)carbamate (2.6 g, 74% yield) as a white solid. m/z LC-MS (electrospray ionization): 357 [M+H]+.
References
[1] Patent: WO2007/76423, 2007, A2. Location in patent: Page/Page column 92
[2] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 8, p. 2244 - 2248
[3] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 21, p. 5567 - 5571
tert-butyl 4,5-dibromothiophen-2-ylcarbamate Preparation Products And Raw materials
tert-butyl 4,5-dibromothiophen-2-ylcarbamate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Rovathin Foreign Trade Co.,Ltd | 0512-65816829 18662214788 | info@rovathin.com.cn | China | 9959 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Yantai Shengkailun Chemical Technology Co., Ltd. | 13356901049 | mark@sklnchem.cn | China | 9925 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |
