ChemicalBook >> CAS DataBase List >>NSC 756093
NSC 756093
- CAS No.
- 1629908-92-4
- Chemical Name:
- NSC 756093
- Synonyms
- NSC 756093;NSC756093【SML1310】;NSC756093 >=98% (HPLC);NSC756093, 10 mM in DMSO;4-(2-hydroxyethyl)-6-methoxy-9-phenyl-3,9-dihydrofuro[3,4-b]quinolin-1-one;4,9-Dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenylfuro[3,4-b]quinolin-1(3H)-one;4-(2-Hydroxyethyl)-6-methoxy-9-phenyl-4,9-dihydrofuro[3,4-b]quinolin-1(3H)-one;Furo[3,4-b]quinolin-1(3H)-one, 4,9-dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenyl-;paclitaxel resistant,anticancer,NSC756093,ovarian cancer,NCI-60 cell,inhibit,SKOV3 cells,Inhibitor
- CBNumber:
- CB93146344
- Molecular Formula:
- C20H19NO4
- Molecular Weight:
- 337.37
- MDL Number:
- MFCD28902215
- MOL File:
- 1629908-92-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-16 07:06:08
| Boiling point | 561.8±50.0 °C(Predicted) |
|---|---|
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| form | A solid |
| pka | 14.56±0.10(Predicted) |
| color | White to off-white |
| InChI | 1S/C20H19NO4/c1-24-14-7-8-15-16(11-14)21(9-10-22)17-12-25-20(23)19(17)18(15)13-5-3-2-4-6-13/h2-8,11,18,22H,9-10,12H2,1H3 |
| InChIKey | SMEJQLRLHKWIFV-UHFFFAOYSA-N |
| SMILES | OCCN1C2=C(C(OC2)=O)C(C3=CC=CC=C3)C4=C1C=C(OC)C=C4 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H400 | |||||||||
| Precautionary statements | P264-P270-P273-P301+P312-P330-P391-P501 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 |
|||||||||
| NFPA 704 |
|
NSC 756093 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1310 | NSC756093 ≥98% (HPLC) | 1629908-92-4 | 5 mg | $111 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML1310 | NSC756093 ≥98% (HPLC) | 1629908-92-4 | 25 mg | $295 | 2026-04-30 | Buy |
| Cayman Chemical | 35023 | NSC 756093 ≥98% | 1629908-92-4 | 1mg | $38 | 2026-04-30 | Buy |
| Cayman Chemical | 35023 | NSC 756093 ≥98% | 1629908-92-4 | 5mg | $120 | 2026-04-30 | Buy |
| Cayman Chemical | 35023 | NSC 756093 ≥98% | 1629908-92-4 | 10mg | $218 | 2026-04-30 | Buy |
NSC 756093 Chemical Properties, Uses, Production
Uses
NSC756093 is the first inhibitor of the GBP1 and PIM1 interaction.
Biological Activity
NSC756093, a podophyllotoxin analog, is a potent and specific inhibitor of GBP1:PIM1 interaction th at inhibits proliferation of paclitaxel resistant cancer cells. Apparently, NSC756093 stabilizes a conformation of GBP1 not suitable for binding to PIM1.
NSC 756093 Preparation Products And Raw materials
Raw materials
Preparation Products
NSC 756093 Suppliers
Global Suppliers ( 33)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4859 | 55 | |
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2994 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2969 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Shanghai Yu Ben Biotechnology Co., Ltd. | 021-61350663 15502154572 | 1639466865@qq.com | China | 499 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Amel Pharmatech Corporation | 027-888-4366503 13986279625 | sales@amelpharmatech.com | China | 4826 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
1629908-92-4 (NSC 756093) Related Search:
NSC 756093
4-(2-hydroxyethyl)-6-methoxy-9-phenyl-3,9-dihydrofuro[3,4-b]quinolin-1-one
NSC756093 >=98% (HPLC)
paclitaxel resistant,anticancer,NSC756093,ovarian cancer,NCI-60 cell,inhibit,SKOV3 cells,Inhibitor
Furo[3,4-b]quinolin-1(3H)-one, 4,9-dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenyl-
4-(2-Hydroxyethyl)-6-methoxy-9-phenyl-4,9-dihydrofuro[3,4-b]quinolin-1(3H)-one
4,9-Dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenylfuro[3,4-b]quinolin-1(3H)-one
NSC756093, 10 mM in DMSO
NSC756093【SML1310】
1629908-92-4







