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NSC 756093

CAS No.
1629908-92-4
Chemical Name:
NSC 756093
Synonyms
NSC 756093;NSC756093【SML1310】;NSC756093 >=98% (HPLC);NSC756093, 10 mM in DMSO;4-(2-hydroxyethyl)-6-methoxy-9-phenyl-3,9-dihydrofuro[3,4-b]quinolin-1-one;4,9-Dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenylfuro[3,4-b]quinolin-1(3H)-one;4-(2-Hydroxyethyl)-6-methoxy-9-phenyl-4,9-dihydrofuro[3,4-b]quinolin-1(3H)-one;Furo[3,4-b]quinolin-1(3H)-one, 4,9-dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenyl-;paclitaxel resistant,anticancer,NSC756093,ovarian cancer,NCI-60 cell,inhibit,SKOV3 cells,Inhibitor
CBNumber:
CB93146344
Molecular Formula:
C20H19NO4
Molecular Weight:
337.37
MDL Number:
MFCD28902215
MOL File:
1629908-92-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08

NSC 756093 Properties

Boiling point 561.8±50.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble
form A solid
pka 14.56±0.10(Predicted)
color White to off-white
InChI 1S/C20H19NO4/c1-24-14-7-8-15-16(11-14)21(9-10-22)17-12-25-20(23)19(17)18(15)13-5-3-2-4-6-13/h2-8,11,18,22H,9-10,12H2,1H3
InChIKey SMEJQLRLHKWIFV-UHFFFAOYSA-N
SMILES OCCN1C2=C(C(OC2)=O)C(C3=CC=CC=C3)C4=C1C=C(OC)C=C4
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H400
Precautionary statements  P264-P270-P273-P301+P312-P330-P391-P501
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Acute 1
NFPA 704
0
2 0

NSC 756093 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1310 NSC756093 ≥98% (HPLC) 1629908-92-4 5 mg $111 2026-04-30 Buy
Sigma-Aldrich SML1310 NSC756093 ≥98% (HPLC) 1629908-92-4 25 mg $295 2026-04-30 Buy
Cayman Chemical 35023 NSC 756093 ≥98% 1629908-92-4 1mg $38 2026-04-30 Buy
Cayman Chemical 35023 NSC 756093 ≥98% 1629908-92-4 5mg $120 2026-04-30 Buy
Cayman Chemical 35023 NSC 756093 ≥98% 1629908-92-4 10mg $218 2026-04-30 Buy
Product number Packaging Price Buy
SML1310 5 mg $111 Buy
SML1310 25 mg $295 Buy
35023 1mg $38 Buy
35023 5mg $120 Buy
35023 10mg $218 Buy

NSC 756093 Chemical Properties, Uses, Production

Uses

NSC756093 is the first inhibitor of the GBP1 and PIM1 interaction.

Biological Activity

NSC756093, a podophyllotoxin analog, is a potent and specific inhibitor of GBP1:PIM1 interaction th at inhibits proliferation of paclitaxel resistant cancer cells. Apparently, NSC756093 stabilizes a conformation of GBP1 not suitable for binding to PIM1.

NSC 756093 Preparation Products And Raw materials

Raw materials

Preparation Products

NSC 756093 Suppliers

Global Suppliers ( 33)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4859 55
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2994 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2969 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 13301690235 Sales@ATKchemical.com China 9729 58
Shanghai Yu Ben Biotechnology Co., Ltd. 021-61350663 15502154572 1639466865@qq.com China 499 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Amel Pharmatech Corporation 027-888-4366503 13986279625 sales@amelpharmatech.com China 4826 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58

View Latest Price from NSC 756093 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NSC756093 pictures 2026-07-16 NSC756093
1629908-92-4
$34.00-95.00 99.92% 10g TargetMol Chemicals Inc.
  • NSC756093 pictures
  • NSC756093
    1629908-92-4
  • $34.00-95.00
  • 99.92%
  • TargetMol Chemicals Inc.

NSC 756093 Spectrum

NSC 756093 4-(2-hydroxyethyl)-6-methoxy-9-phenyl-3,9-dihydrofuro[3,4-b]quinolin-1-one NSC756093 >=98% (HPLC) paclitaxel resistant,anticancer,NSC756093,ovarian cancer,NCI-60 cell,inhibit,SKOV3 cells,Inhibitor Furo[3,4-b]quinolin-1(3H)-one, 4,9-dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenyl- 4-(2-Hydroxyethyl)-6-methoxy-9-phenyl-4,9-dihydrofuro[3,4-b]quinolin-1(3H)-one 4,9-Dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenylfuro[3,4-b]quinolin-1(3H)-one NSC756093, 10 mM in DMSO NSC756093【SML1310】 1629908-92-4