GSK106 (hydrochloride)
- CAS No.
- 1652591-82-6
- Chemical Name:
- GSK106 (hydrochloride)
- Synonyms
- GSK106;GSK106 (hydrochloride);(4-(1-methyl-2-(1-ethylindolin-3-yl)-1H-benzo[d]imidazole-6-carbonyl)piperidin-3-amine hydrochloride;(3-Amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-methanone Hydrochloride
- CBNumber:
- CB93152622
- Molecular Formula:
- C24H28ClN5O
- Molecular Weight:
- 437.965
- MDL Number:
- MFCD33029315
- MOL File:
- 1652591-82-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| GSK106 (hydrochloride) ≥98% | 17490 | 500μg | $41 |
| GSK106 (hydrochloride) ≥98% | 17490 | 1mg | $75 |
| GSK106 (hydrochloride) ≥98% | 17490 | 5mg | $312 |
| GSK106 (hydrochloride) ≥98% | 17490 | 10mg | $544 |
| GSK106 98.28% | CS-0077630 | 5mg | $244 |
GSK106 (hydrochloride) price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17490 | GSK106 (hydrochloride) ≥98% | 1652591-82-6 | 500μg | $41 | 2026-04-30 | Buy |
| Cayman Chemical | 17490 | GSK106 (hydrochloride) ≥98% | 1652591-82-6 | 1mg | $75 | 2026-04-30 | Buy |
| Cayman Chemical | 17490 | GSK106 (hydrochloride) ≥98% | 1652591-82-6 | 5mg | $312 | 2026-04-30 | Buy |
| Cayman Chemical | 17490 | GSK106 (hydrochloride) ≥98% | 1652591-82-6 | 10mg | $544 | 2026-04-30 | Buy |
| ChemScene | CS-0077630 | GSK106 98.28% | 1652591-82-6 | 5mg | $244 | 2026-06-04 | Buy |
GSK106 (hydrochloride) Chemical Properties,Uses,Production
Description
Protein arginine deiminase 4 (PAD4) mediates the transformation of protein arginine into citrulline. Citrullination of proteins has normal roles in gene regulation and pathological roles in immunological and inflammatory diseases. GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199 . It does not inhibit PAD4 nor does it prevent the citrullination of PAD4 target proteins or the formation of neutrophil extracellular traps in mouse or human neutrophils (IC50s > 100 μM). See the Structural Genomics Consortium (SGC) website for more information on both GSK484 and GSK106.
Uses
(3-Amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-methanone Hydrochloride is structurally similar to (3-Amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone TFA Salt (G797395) and is suitable to use as a control to identify inhibitors for protein arginine deiminase 4 (PAD4).
GSK106 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
GSK106 (hydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4853 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4058 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 972 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 4565 | 58 |
