Ortataxel
- CAS No.
- 1613081-64-3
- Chemical Name:
- Ortataxel
- Synonyms
- Ruzasvir (MK-8408);RuzasvirQ: What is Ruzasvir Q: What is the CAS Number of Ruzasvir;DIMETHYL ((2S,2S)-((2S,2S)-(((S)-6-(2-CYCLOPROPYLTHIAZOL-5-YL)-1-FLUORO-6H-BENZO[5,6][1,3]OXAZINO[3,4-A]INDOLE-3,10-DIYL)BIS(1H-IMIDAZOLE-5,2-DIYL))BIS(PYRROLIDINE-2,1-DIYL))BIS(3-METHYL-1-OXOBUTANE-1,2-DIYL))DICARBAMATE;Carbamic acid, N,N'-[[(6S)-6-(2-cyclopropyl-5-thiazolyl)-1-fluoro-6H-indolo[1,2-c][1,3]benzoxazine-3,10-diyl]bis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C'-dimethyl ester
- CBNumber:
- CB93159944
- Molecular Formula:
- C49H55FN10O7S
- Molecular Weight:
- 947.09
- MDL Number:
- MFCD30747903
- MOL File:
- 1613081-64-3.mol
- MSDS File:
- SDS
| Density | 1.52±0.1 g/cm3(Predicted) |
|---|---|
| pka | 11.22±0.46(Predicted) |
| FDA UNII | LX752BD95Y |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H371 |
| Precautionary statements | P260-P264-P270-P309+P311-P405-P501 |
Ortataxel price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0021757 | Ruzasvir 95.82% | 1613081-64-3 | 1mg | $217 | 2026-06-04 | Buy |
| ChemScene | CS-0021757 | Ruzasvir 95.82% | 1613081-64-3 | 5mg | $555 | 2026-06-04 | Buy |
| ChemScene | CS-0021757 | Ruzasvir 95.82% | 1613081-64-3 | 10mg | $807 | 2026-06-04 | Buy |
| aablocks | AA01LGZC | Ruzasvir (MK-8408) | 1613081-64-3 | 1mg | $151 | 2026-05-30 | Buy |
| aablocks | AA01LGZC | Ruzasvir (MK-8408) | 1613081-64-3 | 5mg | $359 | 2026-05-30 | Buy |
Ortataxel Chemical Properties, Uses, Production
Uses
Ruzasvir (MK-8408) is an orally active inhibitor for genotypic HCV nonstructural protein 5A (NS5A), which inhibits the replication of NS5A mutants GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a and GT4a with EC90 ranging from 0.003 to 0.067 nM. Ruzasvir exhibits good pharmacokinetic characters in rhesus monkey model[1].
References
[1] Tong L, et al., Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms. J Med Chem. 2017 Jan 12;60(1):290-306. DOI:10.1021/acs.jmedchem.6b01310
Ortataxel Preparation Products And Raw materials
Raw materials
Preparation Products
Ortataxel Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Jinan Kabotang Biological Technology Co.,Ltd. | 0531-61320525 15866703830 | figo.gao@foxmail.com | China | 7601 | 58 |
| Suzhou Rovathin Foreign Trade Co.,Ltd | 0512-65816829 18662214788 | info@rovathin.com.cn | China | 9962 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6288 | 58 |
| Chunchuang (Wuhan) Technology Co., Ltd | 15727060112 | yutianchun2007@126.com | China | 9867 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 13611835272 13611835272 | mmwang@sunwaypharm.com | China | 44090 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| chemfish tokyo co.,ltd | 85521272 18229978283 | sales@chemfish.com | China | 3585 | 58 |






