Fmoc-aminooxy-PEG4-acid
- CAS No.
- 1895922-70-9
- Chemical Name:
- Fmoc-aminooxy-PEG4-acid
- Synonyms
- Fmoc-aminooxy-PEG4-acid;FmocHNO-PEG4-CH2CH2COOH;Fmoc-aminooxy-PEG4-acid fmoc;3,6,9,12,15-Pentaoxa-2-azaoctadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester;3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)oxyethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
- CBNumber:
- CB93162953
- Molecular Formula:
- C26H33NO9
- Molecular Weight:
- 503.54
- MDL Number:
- MFCD29764345
- MOL File:
- 1895922-70-9.mol
Fmoc-aminooxy-PEG4-acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114417 | Fmoc-aminooxy-PEG4-acid ≥97% | 1895922-70-9 | 1g | $341 | 2026-06-04 | Buy |
| ChemScene | CS-0114417 | Fmoc-aminooxy-PEG4-acid ≥97% | 1895922-70-9 | 5g | $1194 | 2026-06-04 | Buy |
| BroadPharm | bp-23137 | Fmoc-aminooxy-PEG4-acid 98% | 1895922-70-9 | 100MG | $320 | 2026-05-24 | Buy |
| BroadPharm | bp-23137 | Fmoc-aminooxy-PEG4-acid 98% | 1895922-70-9 | 250MG | $580 | 2026-05-24 | Buy |
| BroadPharm | bp-23137 | Fmoc-aminooxy-PEG4-acid 98% | 1895922-70-9 | 500MG | $950 | 2026-05-24 | Buy |
Fmoc-aminooxy-PEG4-acid Chemical Properties, Uses, Production
Description
Fmoc-aminooxy-PEG4-acid is a PEG linker with aminooxy group protected by Fmoc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.
Uses
Fmoc-aminooxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-aminooxy-PEG4-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1978 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38904 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
