FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
- CAS No.
- 557756-85-1
- Chemical Name:
- FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
- Synonyms
- FMoc-NH-PEG4-CH2CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid;Fmoc-NH-PEG4-COOH;Fmoc-NH-(PEG)3-COOH;Fmoc-PEG4-propionic acid;3-[2-[2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propionic acid;Fmoc-PEG4-OH;FMOC-15-AMINO-4;FmocNH-PEG5-acid;Fmoc-NH-PEG4c-COOH
- CBNumber:
- CB5201606
- Molecular Formula:
- C26H33NO8
- Molecular Weight:
- 487.54
- MDL Number:
- MFCD06656472
- MOL File:
- 557756-85-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Fmoc-NH-(PEG)₃-COOH (16 atoms) Novabiochem® | 8.51035 | 1 g | $625 |
| FmocNH-PEG4-CH2CH2COOH 98+% | AS115286 | 5G | $658 |
| Fmoc-NH-PEG4-CH2CH2COOH 98.75% | CS-W000434 | 10g | $675 |
| Fmoc-NH-PEG(4)-COOH | PEG1820 | 5G | $675 |
| Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoicacid | JK992268 | 250mg | $701 |
| More product size | |||
| Boiling point | 682.1±55.0 °C(Predicted) |
|---|---|
| Density | 1.219 |
| storage temp. | -20°C |
| solubility | Soluble in DMSO, DCM, DMF |
| pka | 4.28±0.10(Predicted) |
| form | solid or viscous liquid |
| color | Colorless to light yellow |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29) |
| InChIKey | NUHRPLKTAAVHCZ-UHFFFAOYSA-N |
| SMILES | C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCC(O)=O |
| UNSPSC Code | 51171641 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P301+P312-P362+P364 |
| Safety Statements | 24/25 |
| WGK Germany | WGK 2 |
| HS Code | 29225090 |
| Storage Class | 11 - Combustible Solids |
FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.51035 | Fmoc-NH-(PEG)₃-COOH (16 atoms) Novabiochem® | 557756-85-1 | 1 g | $625 | 2026-03-19 | Buy |
| Activate Scientific | AS115286 | FmocNH-PEG4-CH2CH2COOH 98+% | 557756-85-1 | 5G | $658 | 2021-12-16 | Buy |
| ChemScene | CS-W000434 | Fmoc-NH-PEG4-CH2CH2COOH 98.75% | 557756-85-1 | 10g | $675 | 2021-12-16 | Buy |
| Iris Biotech GmbH | PEG1820 | Fmoc-NH-PEG(4)-COOH | 557756-85-1 | 5G | $675 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK992268 | Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoicacid | 557756-85-1 | 250mg | $701 | 2021-12-16 | Buy |
FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Chemical Properties,Uses,Production
Description
Fmoc-N-amido-PEG4-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical Properties
Yellow oil
Uses
Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
reaction suitability
reaction type: Pegylations
reagent type: cross-linking reagent
IC 50
Cleavable Linker; PEGs
References
[1] Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14. DOI:10.1021/acs.orglett.9b02132
FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| LAURENT | +8618100176782 | sun@laurentpeg.com | China | 365 | 58 |
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29827 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2176 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32469 | 58 |
View Lastest Price from FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-12 | Fmoc-NH-PEG4-CH2CH2COOH
557756-85-1
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2026-02-05 | 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid
557756-85-1
|
US $0.00-0.00 / g | 1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. | |
 |
2026-01-28 | Fmoc-NH-PEG4-CH2CH2COOH
557756-85-1
|
US $0.00-0.00 / g | 1g | 98% | 300kg | LAURENT |
-
- Fmoc-NH-PEG4-CH2CH2COOH
557756-85-1
- US $0.00 / mg
- TargetMol Chemicals Inc.
-
- 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid
557756-85-1
- US $0.00-0.00 / g
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-
- Fmoc-NH-PEG4-CH2CH2COOH
557756-85-1
- US $0.00-0.00 / g
- 98%
- LAURENT
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