ChemicalBook >> CAS DataBase List >>(S)-(+)-2-Amino-3-methyl-1-butanol

(S)-(+)-2-Amino-3-methyl-1-butanol

(S)-(+)-2-Amino-3-methyl-1-butanol structure

CAS No.: 2026-48-4

Chemical Name:: (S)-(+)-2-Amino-3-methyl-1-butanol

Synonyms: L-VALINOL;S-VALINOL;L-VALINAL;M0;H-VAL-OL;l-2-amino-3-methylbutan-1-ol;L-2-AMINO-3-METHYL-1-BUTANOL;(S)-2-AMINO-3-METHYL-1-BUTANOL;(2S)-2-AMINO-3-METHYL-BUTAN-1-OL;val-ol

CBNumber:: CB9319657

Molecular Formula:: C5H13NO

Molecular Weight:: 103.16

MDL Number:: MFCD00064296

MOL File:: 2026-48-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-08 07:26:47

Request For Quotation

(S)-(+)-2-Amino-3-methyl-1-butanol Properties

Melting point	30-34 °C
Boiling point	81 °C8 mm Hg(lit.)
alpha	16 º (c=10,EtOH)
Density	0.926 g/mL at 25 °C(lit.)
refractive index	n20/D 1.4548(lit.)
Flash point	196 °F
storage temp.	Store at +2°C to +8°C.
solubility	DMSO (Slightly), Methanol (Slightly)
form	Liquid After Melting
pka	12.82±0.10(Predicted)
color	Clear slightly yellow
optical activity	[α]25/D +10°, c = 10 in H2O
Water Solubility	Soluble in water.
Sensitive	Air Sensitive
BRN	1719137
InChI	1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3/t5-/m1/s1
InChIKey	NWYYWIJOWOLJNR-RXMQYKEDSA-N
SMILES	CC(C)[C@H](N)CO
CAS DataBase Reference	2026-48-4(CAS DataBase Reference)
FDA UNII	R54N4NJ3ZZ
NIST Chemistry Reference	(S)-(+)-2-Amino-3-methyl-1-butanol(2026-48-4)
UNSPSC Code	12352104
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36-36/37/38

Safety Statements

26-24/25-36

WGK Germany

10-23

HazardClass

IRRITANT

HS Code

29221980

Storage Class

10 - Combustible liquids

NFPA 704

	2
2		1

(S)-(+)-2-Amino-3-methyl-1-butanol price More Price(79)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	186708	(S)-(+)-2-Amino-3-methyl-1-butanol 96%	2026-48-4	1g	$59.6	2026-04-30	Buy
Sigma-Aldrich	186708	(S)-(+)-2-Amino-3-methyl-1-butanol 96%	2026-48-4	5g	$96.6	2026-04-30	Buy
Sigma-Aldrich	8.14082	(S)-(+)-2-Amino-3-methyl-1-butanol for synthesis	2026-48-4	1mL	$12.3	2024-03-01	Buy
TCI Chemical	V0058	L-Valinol >97.0%(GC)(T)	2026-48-4	5g	$49	2026-04-30	Buy
TCI Chemical	V0058	L-Valinol >97.0%(GC)(T)	2026-48-4	25g	$175	2026-04-30	Buy

Product number	Packaging	Price	Buy
186708	1g	$59.6	Buy
186708	5g	$96.6	Buy
8.14082	1mL	$12.3	Buy
V0058	5g	$49	Buy
V0058	25g	$175	Buy

(S)-(+)-2-Amino-3-methyl-1-butanol Chemical Properties, Uses, Production

Chemical Properties

white to light yellow crystal powde

Uses

L-Valinol is used as a reagent in the synthesis of simple 1,3-thiazolidine-2-thione derivatives which can exhibit fungicidal activity. L-Valinol is also used as a reagent in the synthesis of small-molecule inhibitors of MDM2-p53 protein-protein interaction (MDM2 inhibitors) in clinical trials for the treatment of cancer.

Uses

(S)-(+)-2-Amino-3-methyl-1-butanol can be used to prepare:

Imines and oxazolines by reacting with aldehydes and nitriles, respectively.
Chiral oxazoline derived multidentate ligands containing cyclophosphazene moiety.

Purification Methods

Purify S-valinol by vacuum distillation using a short Vigreux column (p 11). Alternatively it is purified by steam distillation. The steam distillate is acidified with HCl; the aqueous layer is collected and evaporated. The residue is dissolved in butan-1-ol, filtered and dry Et2O added to crystallise the hydrochloride salt (hygroscopic), m 113o. The free base can be obtained by suspending the salt in Et2O and adding small volumes of saturated aqueous K2CO3 until effervescence is complete and the mixture is distinctly alkaline. At this stage the aqueous layer should appear as a white sludge. The mixture is heated to boiling and refluxed for 30minutes (more Et2O is added if necessary). Purification of Biochemicals — Amino Acids and Peptides The Et2O layer is decanted off from the white sludge, the sludge is extracted twice with Et2O (by boiling for a few minutes), the combined organic layers are dried (KOH pellets), evaporated and the residue is distilled in a vacuum. [Nagao et al. J Org Chem 55 1148 1990, Beilstein 4 III 805.]

(S)-(+)-2-Amino-3-methyl-1-butanol Preparation Products And Raw materials

Raw materials

Preparation Products

(4S 4's)-(-)-2 2'-(3-pentylidene)bis(4-& (S)-4,5-Dihydro-2-(2-((S)-4,5-dihydro-4-isopropyloxazol-2-yl)propan-2-yl)-4-isopropyloxazole (S)-(+)-4-Isopropyl-3-propionyl-2-oxazolidinone (S,S)-2,6-Bis(4-isopropyl-2-oxazolin-2-yl)pyridine 1-[(4S)-4-(1-Methylethyl)-2-thioxo-3-oxazolidinyl]-

Carbamic acid, [(1R)-1,2-dimethylpropyl]-, 1,1-dimethylethyl ester (9CI) 5-isopropylmorpholin-3-one Cyclo(-Val-Val) (S)-4-(1-Isopropyl)-3-(1-oxobutyl)-2-oxazolidinone (S)-1-Methoxymethyl-2-methyl-propylamine

1of2

(S)-(+)-2-Amino-3-methyl-1-butanol Suppliers

Global Suppliers ( 526)

Supplier	Tel	Email	Country	ProdList	Advantage
Shandong Welt Chem. Co .Ltd	531-87153728 13805401165	xufeng192@126.com	China	106	58
Shandong Welt Chem. Co.,Ltd.	531-87153728 13805401165	xufeng192@126.com	China	5858	58
Yanggu Rongke Trading Co. , Ltd.	0635-6725226 15863541132	yglida@163.com	China	61	65
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
ITIC MEDCHEM(SUZHOU) CO.,LTD.	0512-68323967 18015559028	sales@iticmedchem.com	China	528	61
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55

Supplier	Advantage
Shandong Welt Chem. Co .Ltd	58
Shandong Welt Chem. Co.,Ltd.	58
Yanggu Rongke Trading Co. , Ltd.	65
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
INTATRADE GmbH	66
ITIC MEDCHEM(SUZHOU) CO.,LTD.	61
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Beijing HwrkChemical Technology Co., Ltd	55

View Latest Price from (S)-(+)-2-Amino-3-methyl-1-butanol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-15	L-Val-OL 2026-48-4		1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2026-09-02	(S)-(+)-2-Amino-3-methyl-1-butanol 2026-48-4	$5.00	1KG	99%		Henan Fengda Chemical Co., Ltd
2026-07-07	(S)-(+)-2-Amino-3-methyl-1-butanol 2026-48-4		1kg	98%	1000kgs	Shaanxi Dideu New Materials Co. Ltd

L-Val-OL
2026-48-4
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

(S)-(+)-2-Amino-3-methyl-1-butanol
2026-48-4
$5.00
99%
Henan Fengda Chemical Co., Ltd

(S)-(+)-2-Amino-3-methyl-1-butanol
2026-48-4
$0.00
98%
Shaanxi Dideu New Materials Co. Ltd

(S)-(+)-2-Amino-3-methyl-1-butanol Spectrum

(S)-(+)-2-Amino-3-methyl-1-butanol(2026-48-4)MS (S)-(+)-2-Amino-3-methyl-1-butanol(2026-48-4)¹HNMR (S)-(+)-2-Amino-3-methyl-1-butanol(2026-48-4)¹³CNMR (S)-(+)-2-Amino-3-methyl-1-butanol(2026-48-4)IR1 (S)-(+)-2-Amino-3-methyl-1-butanol(2026-48-4)Raman

2026-48-4 ((S)-(+)-2-Amino-3-methyl-1-butanol) Related Search:

3-Aminophenol Ketorolac tromethamine Fosfomycin tromethamine 3-Methyl-1-butanol 1-Butanol

(R)-TERT-LEUCINOL Methylparaben Kresoxim-methyl VALINOMYCIN Bensulfuron methyl

6-Aminocaproic acid Methyl acrylate Thiophanate-methyl Hydrogenated Cottonseed Oil Glycine

tert-Butanol Aminoethoxyvinyl glycine hydrochloride Dexketoprofen trometamol

1of4

L-VALINAL (+)-L-VALINOL L-(+)-VALINOL L-2-AMINO-3-METHYL-1-BUTANOL l-2-amino-3-methylbutan-1-ol H-VALINOL H-VAL-OL H-L-VAL-OL L-Valinol ,98% (S)-2-Isopropyl-2-aminoethanol (S)-(+)-2-Amino-3-methyl-1-butanol,96% L-Valinol ,98% [ee: 95%] L-Valinol ,95% (S)-(+)-2-Amino-3-me L-Valino (S)-(+)-2-AMino-3-Methyl-1-butanol, 96% 1ML (S)-(+)-2-AMINO-3-METHYL-1-BUTANOL FOR S (S)-(+)-2-Amino-3-methyl-1-butanol(L-Valinal) L-Valinol, 98%, ee: 95% PKC PharMaceuticals, Inc. L - valerian aMMonia alcohol L-(+)-Valinol (S)-(+)-2-Amino-3-methyl-1-butanol L-2-Amino-3-methylbutan-1-ol (S)-(+)-2-Amino-3-methyl-1-butanol 96% L-Valinol Free Base L-Valinol, ee: 95% L-Valinol≥ 98% (GC) L-Valinol,99%e.e. L-Valinol,Elvitegravir intermediate 1-Butanol, 2-amino-3-methyl-, (S)- (S)-(+)-2-Amino-3-methyl-1-butanol~H-Val-ol Valinol,97% (R)-(+)-2-Amino-3-methyl-1-butanolL-Valanol L-Valinol(S)-(+)-2-Amino-3-methyl-1-butanol L-Valanol (S)-(+)-2-AMINO-3-METHYL-1-BUTANOL, 96% (95% EE/GLC) L-Val-ol (S)-2-AMINO-3-METHYL-1-BUTANOL 98.0% 1-Butanol, 2-amino-3-methyl-, (2S)- (S)-2-AMINO-3-METHYL-L-BUTANOL (S)-(+)-2-AMINO-3-METHYL-BUTANOL (S)-2-AMINO-3-METHYL-BUTAN-1-OL (S)-(+)-2-AMINO-3-METHYL-1-BUTANOL (S)-2-AMINO-3-METHYL-1-BUTANOL S-(-)-2-AMINO-3-METHYL-1-BUTANOL H-Val-ol (S)-(+)-2-Amino-3-methyl-1-butanol) -(+)-VaL (S)-(+)-2-Amino-3-methyl-1-butanol USP/EP/BP AMG-232-008 (+)-Valinol val-ol L-2-Amino-3-methyl-1-butanol, L-Valinol (S)-(+)-2-Amino-3-methyl-1-butanol L-(+)-Valinol, 97% (2S)-2-AMINO-3-METHYL-BUTAN-1-OL L-VALINOL M0 S-VALINOL 2026-48-4