RAPANONE
- CAS No.
- 573-40-0
- Chemical Name:
- RAPANONE
- Synonyms
- RAPANONE;RAMATROBAN(RG);Rapanone, 10 mM in DMSO;2,5-dihydroxy-3-tridecyl-p-benzoquinone;2,5-DIHYDROXY-3-TRIDECYL-[1,4]BENZOQUINONE;2,5-Dihydroxy-3-tridecyl-2,5-cyclohexadiene-1,4-dione;2,5-dihydroxy-3-tridecylcyclohexa-2,5-diene-1,4-dione;2,5-dihydroxy-3-tridecyl-cyclohexa-2,5-diene-1,4-dione;2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3-tridecyl-;antioxidant,anti-inflammatory,Bacterial,inhibit,anti-tumor,Phospholipase,antiparasiti,synovial,PLA2,Parasite,benzoquinone,antibacterial,Apoptosis,Rapanone,Inhibitor
- CBNumber:
- CB9345395
- Molecular Formula:
- C19H30O4
- Molecular Weight:
- 322.44
- MDL Number:
- MFCD00075883
- MOL File:
- 573-40-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Rapanone | FR137931 | 1mg | $324.5 |
| Rapanone 98.81% | CS-0140311 | 5mg | $130 |
| Rapanone 98.81% | CS-0140311 | 10mg | $184 |
| Rapanone | BA1382 | 5mg | $108 |
| Rapanone | BA1382 | 1mL(10mMinDMSO) | $118 |
| Melting point | 142-145°C |
|---|---|
| Boiling point | 457.0±45.0 °C(Predicted) |
| Density | 1.099±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| pka | 2.84±0.50(Predicted) |
| form | Solid |
| color | Light yellow to orange |
| FDA UNII | SH52PPU72X |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H227 |
| Precautionary statements | P501-P210-P280-P370+P378-P403+P235 |
RAPANONE price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FR137931 | Rapanone | 573-40-0 | 1mg | $324.5 | 2026-06-04 | Buy |
| ChemScene | CS-0140311 | Rapanone 98.81% | 573-40-0 | 5mg | $130 | 2026-06-04 | Buy |
| ChemScene | CS-0140311 | Rapanone 98.81% | 573-40-0 | 10mg | $184 | 2026-06-04 | Buy |
| ApexBio Technology | BA1382 | Rapanone | 573-40-0 | 5mg | $108 | 2026-05-06 | Buy |
| ApexBio Technology | BA1382 | Rapanone | 573-40-0 | 1mL(10mMinDMSO) | $118 | 2026-05-06 | Buy |
RAPANONE Chemical Properties,Uses,Production
Uses
Rapanone is a natural benzoquinone. Rapanone exhibits a broad spectrum of biological actions, including anti-tumor, antioxidant, anti-inflammatory, antibacterial and antiparasitic. Rapanone also is a potent and selective human synovial PLA2 inhibitor, with an IC50 of 2.6 μM[1][2][3][4].
Definition
ChEBI: Rapanone is a member of dihydroxy-1,4-benzoquinones.
in vivo
Rapanone (2.5-10 mg/kg; i.p.) exhibits anti-inflammatory effects in the carrageenan paw oedema model in mice[4].
IC 50
PLA2: 2.6 μM (IC50)
References
[1] Andreu GLP, et, al. Rapanone, a naturally occurring benzoquinone, inhibits mitochondrial respiration and induces HepG2 cell death. Toxicol In Vitro. 2020 Mar;63:104737. DOI:10.1016/j.tiv.2019.104737
[2] Morais LS, et, al. Antileishmanial compounds from Connarus suberosus: Metabolomics, isolation and mechanism of action. PLoS One. 2020 Nov 6;15(11):e0241855. DOI:10.1371/journal.pone.0241855
[3] Vega-Hernández K, et, al. Discerning the antioxidant mechanism of rapanone: A naturally occurring benzoquinone with iron complexing and radical scavenging activities. J Inorg Biochem. 2017 May;170:134-147. DOI:10.1016/j.jinorgbio.2017.02.019
[4] Ospina LF, et, al. Inhibition of acute and chronic inflammatory responses by the hydroxybenzoquinonic derivative rapanone. Planta Med. 2001 Dec;67(9):791-5. DOI:10.1055/s-2001-18839
RAPANONE Preparation Products And Raw materials
Raw materials
Preparation Products
RAPANONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +86-18080483897 | sales@biopurify.com | China | 4616 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hubei Ipure Biology Co., Ltd | +8618062405514 | ada@ipurechemical.com | China | 10224 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11674 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
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