1,2-Dihexanoyl-sn-glycero-3-phosphocholine
- CAS No.
- 34506-67-7
- Chemical Name:
- 1,2-Dihexanoyl-sn-glycero-3-phosphocholine
- Synonyms
- DHPC;06:0 PC;PC(6:0/6:0);06:0 PC (DHPC);Dihexanoyllecithin;Dicaproyl-L-α-lecithin;L-α-Dihexanoyllecithin;1,2-Dihexanoyl-sn-glycero-3-PC;dihexanoyl-l-a-phosphatidylcholine;L-A-PHOSPHATIDYLCHOLINE, DICAPROYL
- CBNumber:
- CB9350595
- Molecular Formula:
- C20H40NO8P
- Molecular Weight:
- 453.51
- MDL Number:
- MFCD00050431
- MOL File:
- 34506-67-7.mol
- MSDS File:
- SDS
| storage temp. | −20°C |
|---|---|
| solubility | DMF: > 20 mg/ml; DMSO: > 7 mg/ml; Ethanol: > 30 mg/ml; PBS (pH 7.2): > 250 μg/ml |
| form | solution |
| color | White to off-white |
| InChI | 1S/C20H41NO8P/c1-6-8-10-12-19(22)26-16-18(29-20(23)13-11-9-7-2)17-28-30(24,25)27-15-14-21(3,4)5/h18H,6-17H2,1-5H3,(H,24,25) |
| InChIKey | KGWWHBYICAIILE-UHFFFAOYSA-N |
| SMILES | [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCC)=O)COC(CCCCC)=O)=O |
| UNSPSC Code | 51191904 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H319-H331-H336-H351-H361d-H372-H412 | |||||||||
| Precautionary statements | P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313 | |||||||||
| target organs | Central nervous system, Liver,Kidney | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-38-40-48/20/22-36/38-20/22-63 | |||||||||
| Safety Statements | 36/37-26 | |||||||||
| RIDADR | UN 1888 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Inhalation Acute Tox. 4 Oral Aquatic Chronic 3 Carc. 2 Eye Irrit. 2 Repr. 2 Skin Irrit. 2 STOT RE 1 STOT SE 3 |
|||||||||
| NFPA 704 |
|
1,2-Dihexanoyl-sn-glycero-3-phosphocholine price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P4148 | 1,2-Dihexanoyl-sn-glycero-3-phosphocholine solution, 20mg/mL in chloroform, ≥99% | 34506-67-7 | 100mg | $242 | 2023-06-20 | Buy |
| Cayman Chemical | 25585 | 1,2-Dihexanoyl-sn-glycero-3-PC ≥95% | 34506-67-7 | 25mg | $88 | 2026-04-30 | Buy |
| Cayman Chemical | 25585 | 1,2-Dihexanoyl-sn-glycero-3-PC ≥95% | 34506-67-7 | 50mg | $115 | 2026-04-30 | Buy |
| Cayman Chemical | 25585 | 1,2-Dihexanoyl-sn-glycero-3-PC ≥95% | 34506-67-7 | 100mg | $194 | 2026-04-30 | Buy |
| Cayman Chemical | 25585 | 1,2-Dihexanoyl-sn-glycero-3-PC ≥95% | 34506-67-7 | 250mg | $352 | 2026-04-30 | Buy |
1,2-Dihexanoyl-sn-glycero-3-phosphocholine Chemical Properties, Uses, Production
Description
1,2-Dihexanoyl-sn-glycero-3-PC (DHPC-C6) is a synthetic phospholipid containing the short-chain (6:0) caproic acid inserted at the sn-1 and sn-2 positions. It is a substrate for phospholipase C isolated from B. cereus as well as phospholipase A2 isolated from A. halys blomhoffi and N. naja atra snake venom. DHPC is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
Uses
L-α-Dihexanoyllecithin is used in the targeted delivery of adamantylated peptidoglycan immunomodulators in lipid nanocarriers.
Definition
ChEBI: 1,2-dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine 12:0 in which both acyl groups are specified as hexanoyl. It has a role as a surfactant. It is functionally related to a hexanoic acid.
References
[1] LITTLE C. Phospholipase C from Bacillus cereus. Action on some artificial lecithins.[J]. Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1977, 31 4: 267-272. DOI: 10.3891/acta.chem.scand.31b-0267
[2] K TESHIMA. Role of Ca2+ in the substrate binding and catalytic functions of snake venom phospholipases A2.[J]. Journal of biochemistry, 1989, 106 3: 518-527. DOI: 10.1093/oxfordjournals.jbchem.a122885
1,2-Dihexanoyl-sn-glycero-3-phosphocholine Preparation Products And Raw materials
Raw materials
Preparation Products
1,2-Dihexanoyl-sn-glycero-3-phosphocholine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1978 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Chengdu Huachun Technology Co., Ltd | 400-1166-196 15982826727 | cdhxsj@163.com | China | 14571 | 60 |
| Shanghai BaiShun Biological Technology Co., Ltd | 021-37581181 | sales@chem-mall.com | China | 10314 | 58 |
| Shanghai Zhen Li Biological Technology Co., Ltd | 021-16621358918; 18516310516;16621358918;13045646768 | zhenlipharma888@163.com | China | 19060 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| Beijing OKA biological technology co., LTD | 010-62971590 18548936886 | 3462612863@qq.com | China | 10061 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
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