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AEA-P

AEA-P Structure
AEA-P structure
CAS No.
183323-26-4
Chemical Name:
AEA-P
Synonyms
AEA-P;ANANDAMIDE PHOSPHATE;PZPHIQQEQWCEGG-DOFZRALJSA-N;ARACHIDONOYL ETHANOLAMIDE PHOSPHATE;N-(2-(PHOSPHONOOXY)ETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;5,8,11,14-Eicosatetraenamide, N-[2-(phosphonooxy)ethyl]-, (5Z,8Z,11Z,14Z)-
CBNumber:
CB9378032
Molecular Formula:
C22H38NO5P
Molecular Weight:
427.51
MDL Number:
MFCD08062225
MOL File:
183323-26-4.mol
MSDS File:
SDS
Last updated:2026-05-28 06:04:17
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AEA-P Properties

Density 1.075±0.06 g/cm3(Predicted)
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 5 mg/ml
pka 1.86±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Danger
Hazard statements  H225
Precautionary statements  P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
NFPA 704
3
0 0

AEA-P price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10180 Arachidonoyl Ethanolamide Phosphate ≥98% 183323-26-4 250μg $28 2026-04-30 Buy
Cayman Chemical 10180 Arachidonoyl Ethanolamide Phosphate ≥98% 183323-26-4 500μg $50 2026-04-30 Buy
Cayman Chemical 10180 Arachidonoyl Ethanolamide Phosphate ≥98% 183323-26-4 1mg $94 2026-04-30 Buy
Cayman Chemical 10180 Arachidonoyl Ethanolamide Phosphate ≥98% 183323-26-4 5mg $409 2026-04-30 Buy
ChemScene CS-0138606 Arachidonoyl ethanolamide phosphate 183323-26-4 1mg(2.34mM*1mLinEthanol) $230 2026-06-04 Buy
Product number Packaging Price Buy
10180 250μg $28 Buy
10180 500μg $50 Buy
10180 1mg $94 Buy
10180 5mg $409 Buy
CS-0138606 1mg(2.34mM*1mLinEthanol) $230 Buy

AEA-P Chemical Properties, Uses, Production

Description

Arachidonoyl ethanolamide (AEA; ) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as Δ9-THC . Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol (2-AG; ). The phosphate ester of AEA, AEA-P, has been tested as a water soluble prodrug version of AEA in the treatment of C6 glioma cells in vivo. Here it acts with essentially the same potency as AEA. However, when tested for inhibition of AEA binding to isolated rat brain CB1 receptors, AEA-P is about 5-fold less potent as an agonist with a Ki of about 200 nM. The phosphate esters of AEA and its analogs are also structural variants of lysophosphatidic acid (LPA). However, the effects of AEA-P on the various LPA receptors have not been tested.

Uses

Arachidonoyl ethanolamide phosphate, an endocannabinoid, is an endogenous ligand for cannabinoid receptors in the central nervous system (CB1 subtype) and peripheral immune cells (CB2 subtype)[1][2].

Definition

ChEBI: Phospho-anandamide is a phosphoethanolamine and a N-acylethanolamine phosphate.

References

[1] M Maccarrone, et al. Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. J Biol Chem. 2000 Oct 13;275(41):31938-45. DOI:10.1074/jbc.M005722200
[2] S O Jacobsson, et al. Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors. J Pharmacol Exp Ther. 2001 Dec;299(3):951-9. PMID:11714882

AEA-P Preparation Products And Raw materials

Raw materials

Preparation Products

AEA-P Suppliers

Global Suppliers ( 23)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 18621169109 market03@meryer.com China 27963 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 58
SHANGHAI ZZBIO CO., LTD. 58

183323-26-4 (AEA-P) Related Search:

Anandamide N-(2-Phosphate-1r-methylethyl)-5z,8z,11z,14z-eicosatetraenamide AEA-P N-(2-Hydroxyethyl-1,1,2,2-d4)-5Z,8Z,11Z,14Z-eicosatetraenamide AEA-D8
oxy-Arachidonoyl Ethanolamide Exclusive

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AEA-P ANANDAMIDE PHOSPHATE ARACHIDONOYL ETHANOLAMIDE PHOSPHATE N-(2-(PHOSPHONOOXY)ETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE PZPHIQQEQWCEGG-DOFZRALJSA-N 5,8,11,14-Eicosatetraenamide, N-[2-(phosphonooxy)ethyl]-, (5Z,8Z,11Z,14Z)- 183323-26-4