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Benzyl 2-bromoacetate

Benzyl 2-bromoacetate structure

CAS No.: 5437-45-6

Chemical Name:: Benzyl 2-bromoacetate

Synonyms: BENZYL BROMOACETATE;merbac35;TIMTEC-BB SBB006752;BENZYL 2-BROMOACETATE;Benzyl a-Bromoacetate;BroMine benzyl acetate;Benzylbromoacetate,97%;Benzyl broMoacetate 96%;Bromoacetic acid benzyl;Benzyl Bromoacetate >

CBNumber:: CB9413740

Molecular Formula:: C9H9BrO2

Molecular Weight:: 229.07

MDL Number:: MFCD00000190

MOL File:: 5437-45-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-06-24 18:39:39

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Benzyl 2-bromoacetate Properties

Melting point	199-201 °C(Solv: water (7732-18-5))
Boiling point	166-170 °C22 mm Hg(lit.)
Density	1.446 g/mL at 25 °C(lit.)
refractive index	n20/D 1.544(lit.)
Flash point	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform, Methanol
form	Liquid
Specific Gravity	1.446
color	Clear colorless to light yellow
Water Solubility	Not miscible or difficult to mix in water.
BRN	973658
InChI	1S/C9H9BrO2/c10-6-9(11)12-7-8-4-2-1-3-5-8/h1-5H,6-7H2
InChIKey	JHVLLYQQQYIWKX-UHFFFAOYSA-N
SMILES	BrCC(=O)OCc1ccccc1
LogP	2.368 (est)
CAS DataBase Reference	5437-45-6(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances	BENZYL BROMOACETATE
FDA 21 CFR	175.105
EWG's Food Scores	1
FDA UNII	64U2RK18D3
NIST Chemistry Reference	Benzyl 2-bromoacetate(5437-45-6)
EPA Substance Registry System	Benzyl bromoacetate (5437-45-6)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39

RIDADR

2810

WGK Germany

RTECS

AF5957215

HS Code

29159080

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

REACH Registrations

Active

NFPA 704

	1
2		0

Benzyl 2-bromoacetate price More Price(69)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	245631	Benzyl bromoacetate 96%	5437-45-6	50g	$44.8	2026-04-30	Buy
Sigma-Aldrich	245631	Benzyl bromoacetate 96%	5437-45-6	250g	$149	2026-04-30	Buy
TCI Chemical	B1674	Benzyl Bromoacetate >96.0%(GC)	5437-45-6	25g	$22	2026-04-30	Buy
TCI Chemical	B1674	Benzyl Bromoacetate >96.0%(GC)	5437-45-6	500g	$196	2026-04-30	Buy
TRC	TRC-B679115-50G	2-Bromoacetic Acid Phenylmethyl Ester	5437-45-6	50g	$122	2026-06-03	Buy

Product number	Packaging	Price	Buy
245631	50g	$44.8	Buy
245631	250g	$149	Buy
B1674	25g	$22	Buy
B1674	500g	$196	Buy
TRC-B679115-50G	50g	$122	Buy

Benzyl 2-bromoacetate Chemical Properties, Uses, Production

Chemical Properties

Colorless to light yellow liqui

Uses

It is employed in biological research purpose. Benzyl bromoacetate was used in the alkylation of (-)-2,3-O-isopropylidene-D-threitol that afforded lipopeptide, 2-[(4R,5R)-5-({[(9H-fluoren-9-yl)methoxy]carbonylaminomethyl}-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]acetic acid.

Synthesis

79-08-3

100-51-6

103-50-4

5437-45-6

General method: A mixture of acid 2 (0.033 g), 2-bromoacetic acid (3a) (0.137 g, 0.988 mmol) adsorbed on silica gel and benzyl alcohol (4a) (0.108 g, 1.000 mmol) was stirred and reacted at 80°C for 24 h under argon protection. After completion of the reaction, the mixture was cooled to room temperature, ether (5 mL x 5) was added for extraction, and the organic layer was separated by decantation from the silica gel adsorbed acid 2. The organic layer was concentrated under reduced pressure to remove the solvent, and then purified by silica gel column chromatography to afford benzyl 2-bromoacetate (5aa) (0.189 g, 83% yield) using hexane/ethyl acetate (v/v = 10/1) as eluent. The silica gel adsorbed acid 2 was recovered by vacuum drying at room temperature to give a white powder (0.033 g, 99% recovery).

Purification Methods

Dilute the ester with Et2O, wash it with 10% aqueous NaHCO3, H2O, dry (MgSO4) and fractionate it using a Fenske (glass helices packing) column. [Bergmann & Szinai J Chem Soc 1521 1956, Beilstein 6 IV 2265.] LACHRYMATORY.

References

[1] Journal of Molecular Catalysis A: Chemical, 2013, vol. 367, p. 116 - 120

Benzyl 2-bromoacetate synthesis

Synthesis of Benzyl 2-bromoacetate from Bromoacetic acid and Benzyl alcohol

Benzyl 2-bromoacetate Preparation Products And Raw materials

Raw materials

Bromoacetic acid Benzyl alcohol

Preparation Products

Aceclofenac Acemetacin Benazepril Diethyl (benzyloxycarbonylmethyl)phosphonate, 98 % (4-Methyl-piperazin-1-yl)-acetic acid

2-Amino-6-chloro-9H-purine-9-acetic acid benzyl ester 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-diMethylethyl) phenylMethyl ester 4-Benzyl-morpholin-2-one Acemetacin Impurity 4

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Benzyl 2-bromoacetate Suppliers

Global Suppliers ( 349)

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Hanxuan Biotechnology Co., Ltd	18602598900，18605190599 18602598900	1669093670@qq.com	China	95	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66

Supplier	Advantage
Changzhou Hanxuan Biotechnology Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Beijing HwrkChemical Technology Co., Ltd	55
Energy Chemical	61
Capot Chemical Co., Ltd	66
Beijing Ouhe Technology Co., Ltd	60
Jia Xing Isenchem Co.,Ltd	66

View Latest Price from Benzyl 2-bromoacetate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	benzyl bromoacetate 5437-45-6	$8.00	1KG	99%		Henan Fengda Chemical Co., Ltd
2025-04-04	Benzyl 2-bromoacetate 5437-45-6		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-07-13	Benzyl 2-bromoacetate 5437-45-6	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

benzyl bromoacetate
5437-45-6
$8.00
99%
Henan Fengda Chemical Co., Ltd

Benzyl 2-bromoacetate
5437-45-6
98%
Henan Aochuang Chemical Co.,Ltd.

Benzyl 2-bromoacetate
5437-45-6
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Benzyl 2-bromoacetate Spectrum

Benzyl 2-bromoacetate(5437-45-6)MS Benzyl 2-bromoacetate(5437-45-6)¹HNMR Benzyl 2-bromoacetate(5437-45-6)¹³CNMR Benzyl 2-bromoacetate(5437-45-6)IR1 Benzyl 2-bromoacetate(5437-45-6)Raman

5437-45-6 (Benzyl 2-bromoacetate) Related Search:

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bromo-aceticacibenzylester bromo-aceticaciphenylmethylester acetic acid (phenylmethyl)bromanuidyl ester Benzyl 2-broMoacetate, 96% 50GR Bromoacetic acid benzyl ester, Benzyl bromoethanoate BroMine benzyl acetate 2-Bromoacetic Acid Phenylmethyl Ester Benzyl broMoacetate 96% TIMTEC-BB SBB006752 merbac35 BROMOACETIC ACID BENZYL ESTER BENZYL 2-BROMOACETATE 2-BROMO-ACETIC ACID BENZYLESTER Benzyl-2-Bromoacetate96% Benzylbromoacetate,97% Acetic acid, bromo-, benzyl ester Acetic acid, bromo-, phenylmethyl ester Benzyl a-Bromoacetate bromo-acetic acid phenylmethyl ester Bromoacetic acid benzyl este Phenylmethyl 2-bromoacetate Bromoacetic acid benzyl 1-Bromo-3-oxa-4-phenylbutan-2-one Benzyl 2-broMoacetate, 96% 250GR Benzyl Bromoacetate > Acetic acid, 2-bromo-, phenylmethyl ester BENZYL 2-BROMOACETATE CAS 5437-45-6 BENZYL BROMOACETATE 5437-45-6 BrCH2COOCH2C6H5 C6H5CH2CO2CH2Br HALOGEN Carbonyl Compounds C8 to C9 Building Blocks Organic Building Blocks Esters Building Blocks C8 to C9 Carbonyl Compounds Chemical Synthesis Esters Organic Building Blocks Pharmaceutical Intermediates