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ChemicalBook >> CAS DataBase List >>1,8-Naphthosultam

1,8-Naphthosultam

1,8-Naphthosultam Structure
1,8-Naphthosultam structure
CAS No.
603-72-5
Chemical Name:
1,8-Naphthosultam
Synonyms
1,8-Naphthosultam;1,8-Naphthasultam;1,8-Naphthosultam,98%;1,8-NAPHTHALENESULTAM;2H-naphth[1,8-cd]isothiazole 1,1-dioxide;2H-naphtho[1,8-cd]isothiazole 1,1-dioxide;8-Aminonaphthalene-1-sulfonic acid sultam;1,2-Napthaquinone-4-SulphonicacidSodiumSalt
CBNumber:
CB9417243
Molecular Formula:
C10H7NO2S
Molecular Weight:
205.23
MDL Number:
MFCD00009746
MOL File:
603-72-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:56:28
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1,8-Naphthosultam Properties

Melting point 173-175 °C(lit.)
Boiling point 442.2±28.0 °C(Predicted)
Density 1.3178 (rough estimate)
refractive index 1.5250 (estimate)
storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P261-P305+P351+P338
Safety Statements  22-24/25
WGK Germany  3

1,8-Naphthosultam price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth AAA60372 1,8-Naphthosultam 603-72-5 5g $312.5 2026-06-04 Buy
aablocks AA00ED9A 2H-Naphtho[1,8-Cd]Isothiazole 1,1-Dioxide 97% 603-72-5 1g $40 2026-05-28 Buy
aablocks AA00ED9A 2H-Naphtho[1,8-Cd]Isothiazole 1,1-Dioxide 97% 603-72-5 5g $118 2026-05-28 Buy
aablocks AA00ED9A 2H-Naphtho[1,8-Cd]Isothiazole 1,1-Dioxide 97% 603-72-5 10g $213 2026-05-28 Buy
aablocks AA00ED9A 2H-Naphtho[1,8-Cd]Isothiazole 1,1-Dioxide 97% 603-72-5 25g $474 2026-05-28 Buy
Product number Packaging Price Buy
AAA60372 5g $312.5 Buy
AA00ED9A 1g $40 Buy
AA00ED9A 5g $118 Buy
AA00ED9A 10g $213 Buy
AA00ED9A 25g $474 Buy

1,8-Naphthosultam Chemical Properties, Uses, Production

Chemical Properties

grey-green to brown-grey or grey powder

Synthesis

1-Naphthalenesulfonic acid, 8-amino-, potassium salt (1:1)

16619-06-0

1,8-NAPHTHOSULTAM

603-72-5

General procedure for the synthesis of 1,8-naphthalenesulfonolactam from 1,8-naphthalenesulfonic acid potassium salt (CAS: 16619-06-0): 5 g of 1,8-naphthalenesulfonic acid potassium salt was pulverized and placed in a flask containing 15 g of POCl3. After installation of a reflux condenser, the reaction system is heated in an oil bath to 130°C. When the temperature reaches 100°C, HCl gas starts to be released, which has to be discharged through the flue. To facilitate the reaction, the flask was shaken periodically. After the release of irritating gases stops, the heating is continued until the reaction mixture no longer produces dye in the diazotization and color development test, usually for a reaction time of 3 hours. Due to the slurry-like consistency of the reaction mixture, caution is required to remove excess POCl3. Subsequently, the reaction mixture is quenched by slowly pouring it into an ice bath. The gray solid product was collected by diafiltration and washed repeatedly with water to remove most of the phosphoric acid. The crude product was dried and purified by recrystallization with benzene. Product melting point: 175-180°C; 1H NMR (DMSO-d6, 300 MHz) δ: 8.62 (d, 1H, J = 8.0 Hz), 8.12 (d, 1H, J = 8.0 Hz), 7.75-7.74 (m, 1H), 7.61 (d, 1H, J = 8.0 Hz), 7.32 (dd, 1H, J = 7.5, 6.7 Hz), 6.7 Hz), 6.7 Hz). 6.7 Hz), 6.90 (d, 1H, J = 6.8 Hz), 5.36 (s, 1H); MS (EI): m/z 206 (M++H).

References

[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 2, p. 789 - 800
[2] Tetrahedron, 2014, vol. 70, # 8, p. 1659 - 1690

1,8-Naphthosultam synthesis

16619-06-0
603-72-5
Synthesis of 1,8-Naphthosultam from 1-Naphthalenesulfonic acid, 8-amino-, potassium salt (1:1)

1,8-Naphthosultam Preparation Products And Raw materials

Raw materials

1-Naphthalenesulfonic acid, 8-amino-, potassium salt (1:1)

Preparation Products

2-(2-Bromoethyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide

1,8-Naphthosultam Suppliers

Global Suppliers ( 54)
Supplier Tel Email Country ProdList Advantage
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9961 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Chengdu Huachun Technology Co., Ltd 400-1166-196 15982826727 cdhxsj@163.com China 14571 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55
Shanghai Zhen Li Biological Technology Co., Ltd 021-16621358918; 18516310516;16621358918;13045646768 zhenlipharma888@163.com China 19060 58
Aikon International Limited 025-58851090 13913916777 sales01@aikonchem.com China 15947 58
Supplier Advantage
Shandong Xiya Chemical Co., Ltd 57
Syntechem Co.,Ltd 57
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Shanghai Xingui Biotechnology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Chengdu Huachun Technology Co., Ltd 60
Amadis Chemical Company Limited 58
Yantai ShengKailun Chemical Technology Co., Ltd. 55
Shanghai Zhen Li Biological Technology Co., Ltd 58
Aikon International Limited 58

View Latest Price from 1,8-Naphthosultam manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,8-Naphthosultam pictures 2026-02-02 1,8-Naphthosultam
603-72-5
 1KG 99% 2000tons Shaanxi Dideu Medichem Co. Ltd

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