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4-Nitro-1,3-phenylenediamine

4-Nitro-1,3-phenylenediamine Structure
4-Nitro-1,3-phenylenediamine structure
CAS No.
5131-58-8
Chemical Name:
4-Nitro-1,3-phenylenediamine
Synonyms
4-NITRO-M-PHENYLENEDIAMINE;4-NITRO-1,3-BENZENEDIAMINE;4-Nitrobenzene-1,3-diamine;c.i.76030;3-Amino-4-nitroaniline;LABOTEST-BB LT00053760;2,4-DIAMINONITROBENZENE;4-NITRO-M-BENZENEDIAMINE;4-nitro-3-benzenediamine;4-nitro-m-phenylenediamin
CBNumber:
CB9434172
Molecular Formula:
C6H7N3O2
Molecular Weight:
153.14
MDL Number:
MFCD00025289
MOL File:
5131-58-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:39:36
Request For Quotation

4-Nitro-1,3-phenylenediamine Properties

Melting point 161°C
Boiling point 276.04°C (rough estimate)
Density 1.3682 (rough estimate)
vapor pressure 0.007Pa at 25℃
refractive index 1.6500 (estimate)
solubility almost transparency in hot Methanol
form powder to crystal
pka 0.99±0.10(Predicted)
Colour Index 76030
color Yellow compound in hair dyes
Water Solubility <0.1 g/100 mL at 20.5 ºC
BRN 2094904
Henry's Law Constant 1.7×105 mol/(m3Pa) at 25℃, HSDB (2015)
Cosmetics Ingredients Functions HAIR DYEING
Cosmetic Ingredient Review (CIR) 4-Nitro-1,3-phenylenediamine (5131-58-8)
LogP 0.55
CAS DataBase Reference 5131-58-8(CAS DataBase Reference)
EWG's Food Scores 3-6
FDA UNII 0D5U5EW62Z
EPA Substance Registry System 4-Nitro-m-phenylenediamine (5131-58-8)
UNSPSC Code 12352108
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS07,GHS06,GHS08
Signal word  Warning
Hazard statements  H315-H319-H301-H341
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P201-P301+P310a-P305+P351+P338-P405-P501a
Risk Statements  22-36/38
Safety Statements  26-36/37/39
RTECS  ST2910000
TSCA  TSCA listed
HS Code  2921.51.5000
Hazardous Substances Data 5131-58-8(Hazardous Substances Data)
Toxicity LD50 orl-rat: 4500 mg/kg GTPZAB 35(2),42,91
REACH Registrations Inactive
NFPA 704
0
2 0

4-Nitro-1,3-phenylenediamine price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S595098 4-NITRO-1,3-PHENYLENEDIAMINE AldrichCPR 5131-58-8 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S595098 4-NITRO-1,3-PHENYLENEDIAMINE AldrichCPR 5131-58-8 1G $179 2024-03-01 Buy
TCI Chemical D0104 4-Nitro-1,3-phenylenediamine >98.0%(GC) 5131-58-8 25g $62 2026-04-30 Buy
TRC TRC-N491795-100MG 4-Nitro-1,3-diaminobenzene 5131-58-8 100mg $74 2026-06-03 Buy
ChemScene CS-0010147 4-Nitro-m-phenylenediamine ≥98% 5131-58-8 25g $173 2026-06-04 Buy
Product number Packaging Price Buy
S595098 1 unit $197 Buy
S595098 1G $179 Buy
D0104 25g $62 Buy
TRC-N491795-100MG 100mg $74 Buy
CS-0010147 25g $173 Buy

4-Nitro-1,3-phenylenediamine Chemical Properties, Uses, Production

Chemical Properties

Yellow crystal powder

Uses

4-Nitro-1,3-diaminobenzene is a general chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of potent and selective Chk-1 inhibitors in the treatment of various cancers.

Definition

ChEBI: 4-nitro-1,3-phenylenediamine is a C-nitro compound.

General Description

Orange prisms with blue luster or yellow crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4-Nitro-1,3-phenylenediamine is an amine/organonitrate. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Fire Hazard

Flash point data for 4-Nitro-1,3-phenylenediamine are not available, but 4-Nitro-1,3-phenylenediamine is probably combustible.

Safety Profile

Moderately toxic by ingestion.Mutation data reported. When heated to decomposition itemits toxic vapors of NOx.

4-Nitro-1,3-phenylenediamine synthesis

108-45-2
5131-58-8
Synthesis of 4-Nitro-1,3-phenylenediamine from m-Phenylenediamine

4-Nitro-1,3-phenylenediamine Preparation Products And Raw materials

Raw materials

4-Nitroaniline-3-sulfonicacid 4-methyl-N-[3-[(4-methylphenyl)sulfonylamino]phenyl]benzenesulfonamide 2-Chloro-4,5-dinitro-benzoic acid 2,4-Dichloro-5-nitrobenzoic acid 2-Chloro-1,4-dinitrobenzene
2,6-Dichloro-3-nitrobenzoic acid N,N'-(m-phenylene)di(acetamide) Aniline 2,5-Dinitroaniline m-Phenylenediamine
2-Chloro-4-nitrobenzoic acid Ammonia

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Preparation Products

CCRIS 2546 4-(4-Fluorobenzylamino)-1,2-phenylenediamine Durazol Brown 4RNS 1,4-Benzenedisulfonic acid, 2-[[4-[[4-[(2,4-diamino-5-nitrophenyl)azo]-6-sulfo-1-naphthalenyl]azo]-1-naphthalenyl]azo]-, trisodium salt sodium [3-[[3-[(3-amino-4-nitrophenyl)azo]-2,4-dihydroxyphenyl]azo]-4-hydroxybenzenesulphonato(3-)]cuprate(1-)
Acid BrOWN85 (c.i. 34900)

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4-Nitro-1,3-phenylenediamine Suppliers

Global Suppliers ( 210)
Supplier Tel Email Country ProdList Advantage
Shaanxi Didu New Material Co., Ltd 81124267 17392282731 1046@dideu.com China 10000 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Maya High Purity Chemicals +86 (573) 82222445 (0)18006601000 452520369 sales@maya-r.com China 11693 57
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75
TCI AMERICA 800-4238616 sales@tciamerica.com Americas 23636 75
Supplier Advantage
Shaanxi Didu New Material Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Tianjin heowns Biochemical Technology Co., Ltd. 57
Maya High Purity Chemicals 57
TOKYO CHEMICAL INDUSTRY CO., LTD. 80
TCI Europe 75
TCI AMERICA 75

View Latest Price from 4-Nitro-1,3-phenylenediamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Nitro-1,3-phenylenediamine pictures 2026-08-25 4-Nitro-1,3-phenylenediamine
5131-58-8
 $2.20-8.80 1kg 99%min 1000kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
4-Nitro-1,3-phenylenediamine pictures 2026-06-30 4-Nitro-1,3-phenylenediamine
5131-58-8
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-Nitro-1,3-phenylenediamine pictures 2024-04-15 4-Nitro-1,3-phenylenediamine
5131-58-8
 $25.00 1kg 99% 5000tons Wuhan Boyuan Import & Export Co., LTD

4-Nitro-1,3-phenylenediamine Spectrum

4-Nitro-1,3-phenylenediamine(5131-58-8)MS4-Nitro-1,3-phenylenediamine(5131-58-8)1HNMR4-Nitro-1,3-phenylenediamine(5131-58-8)13CNMR4-Nitro-1,3-phenylenediamine(5131-58-8)IR14-Nitro-1,3-phenylenediamine(5131-58-8)IR2

5131-58-8 (4-Nitro-1,3-phenylenediamine) Related Search:

Benzene-1,3-diamine dihydrochloride o-Phenylenediamine p-Phenylenediamine 4-Nitrobenzonitrile 6-Aminocaproic acid
4-Nitrotoluene m-Phenylenediamine 4-Nitrobenzoic acid 1,3-Phenylenediamine sulfate 3-Aminophenol
1,3-Diaminoguanidine monohydrochloride Tris(hydroxymethyl)aminomethane Glycine Aminoethoxyvinyl glycine hydrochloride DNQX
4-Nitrophenol 2,3,6-Trinitrophenol Nitrogen dioxide

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1,3-benzenediamine,-nitro- 4-nitro-1,3-fenylendiamin c.i.76030 LABOTEST-BB LT00053760 3-Amino-4-nitroaniline 4-nitro-3-benzenediamine 4-nitro-m-phenylenediamin 4-NITRO-1,3-PHENYLENEDIAMINE 4-NITRO-M-PHENYLENEDIAMINE 4-NITRO-M-BENZENEDIAMINE 2,4-DIAMINONITROBENZENE 1,3-DIAMINO-4-NITROBENZENE PARA-NITRO-META-PHENYLENEDIAMINE 4-Nitro-3-phenylenediamine 4-Nitro-m-phenylenediamine,95% (5-amino-2-nitro-phenyl)amine 4-Nirto-1,3-phenylenediaMine 4-NITRO-META-PHENYLENEDIAMINE 4-Nitro-1,3-phenylendiamin 2,4-DIAMINONITROBENZENE / 4-NITRO-1,3-BENZENEDIAMINE P-nitro-m-phenylenediamine 1,3-Benzenediamine, 4-nitro 2,4-Diamino-1-nitrobenzene High quality 4-Nitro-1,3-phenylenediamine CAS NO.5131-58-8 4-Nitro-1,3-phenylenediamine> Elagolix Impurity 56 Sodium Salt 4-NITRO-1,3-BENZENEDIAMINE 4-Nitrobenzene-1,3-diamine 5131-58-8 5231-58-8 5131-58-5 O2NC6H3NH4 Intermediates of Dyes and Pigments