ChemicalBook >> CAS DataBase List >>O-ACETYLSALICYLOYL CHLORIDE
O-ACETYLSALICYLOYL CHLORIDE
- CAS No.
- 5538-51-2
- Chemical Name:
- O-ACETYLSALICYLOYL CHLORIDE
- Synonyms
- ACETYLSALICYLOYL CHLORIDE;2-(Chlorocarbonyl)phenyl acetate;SKL1282;ASPIRIN CHLORIDE;AKOS BBS-00003925;2-(Chlorocarbonyl);O-ACETYLSALICYLOYL C;o-Acetylsalicychloride;Acetylsalicoyl chloride;O-Acetoxybenzoylchloride
- CBNumber:
- CB9446371
- Molecular Formula:
- C9H7ClO3
- Molecular Weight:
- 198.6
- MDL Number:
- MFCD00000663
- MOL File:
- 5538-51-2.mol
- MSDS File:
- SDS
Last updated:2026-05-28 04:50:50
| Product description | Number | Pack Size | Price |
| O-Acetylsalicyloyl chloride 95% | 165190 | 5g | $56.5 |
| O-Acetylsalicyloyl chloride 95% | 165190 | 25g | $89.3 |
| O-Acetylsalicyloyl Chloride >97.0%(HPLC)(T) | A1917 | 5g | $34 |
| O-Acetylsalicyloyl Chloride >97.0%(HPLC)(T) | A1917 | 25g | $108 |
| O-Acetylsalicyloyl Chloride | TRC-A187935-5G | 5g | $129 |
| More product size | |||
| Melting point | 45-49 °C (lit.) |
|---|---|
| Boiling point | 107-110 °C/0.1 mmHg (lit.) |
| Density | 1.3219 (rough estimate) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | powder to lump |
| color | White to Orange to Green |
| Water Solubility | Soluble in toluene. Reacts with water. |
| Sensitive | Moisture Sensitive |
| BRN | 880372 |
| Stability | Moisture Sensitive |
| InChI | 1S/C9H7ClO3/c1-6(11)13-8-5-3-2-4-7(8)9(10)12/h2-5H,1H3 |
| InChIKey | DSGKWFGEUBCEIE-UHFFFAOYSA-N |
| SMILES | CC(=O)Oc1ccccc1C(Cl)=O |
| CAS DataBase Reference | 5538-51-2(CAS DataBase Reference) |
| FDA UNII | 67R3L2L9J7 |
| NIST Chemistry Reference | Acetylsalicyloyl chloride(5538-51-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 22-34-37-29 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10-21 | |||||||||
| Hazard Note | Irritant/Corrosive/Moisture Sensitive | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29163900 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Corr. 1B |
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| NFPA 704 |
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O-ACETYLSALICYLOYL CHLORIDE price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 165190 | O-Acetylsalicyloyl chloride 95% | 5538-51-2 | 5g | $56.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 165190 | O-Acetylsalicyloyl chloride 95% | 5538-51-2 | 25g | $89.3 | 2026-04-30 | Buy |
| TCI Chemical | A1917 | O-Acetylsalicyloyl Chloride >97.0%(HPLC)(T) | 5538-51-2 | 5g | $34 | 2026-04-30 | Buy |
| TCI Chemical | A1917 | O-Acetylsalicyloyl Chloride >97.0%(HPLC)(T) | 5538-51-2 | 25g | $108 | 2026-04-30 | Buy |
| TRC | TRC-A187935-5G | O-Acetylsalicyloyl Chloride | 5538-51-2 | 5g | $129 | 2026-06-03 | Buy |
O-ACETYLSALICYLOYL CHLORIDE Chemical Properties,Uses,Production
Chemical Properties
yellow to light orange chunks
Uses
O-Acetylsalicyloyl chloride was used in the synthesis of enantiomerically pure bidentate heteroorganic ligands built on simple achiral skeletons and containing an aziridine moiety. It was used in the general synthesis of acetoxybenzamides. It was used in the chemical synthesis of 2,2,6,6-tetramethyl-1-piperidinyloxy(TEMPO)-aspirin conjugate via condensation reaction with 4-hydroxy-TEMPO. It was used as reagent in acylation of cyclobutenediones.
Purification Methods
Check first the IR to see if an OH frequency is present. If so, some free acid is present. Then reflux with acetyl chloride for 2-3hours and fractionate at high vacuum. The distillate should crystallise. It can be recrystallised from hexane or *C6H6 (m 60o, sintering at 52o). [Riegel & Wittcoff J Am Chem Soc 64 486 1942, Beilstein 10 H 86, 10 I 43, 10 II 55, 10 III 151, 10 IV 169.]
O-ACETYLSALICYLOYL CHLORIDE Preparation Products And Raw materials
Raw materials
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Preparation Products
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Global( 215)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 | sales1@chuanghaibio.com | China | 5218 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2777 | 58 | |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +86-18627785180 | info@finetechnology-ind.com | China | 9539 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +86-13289823923 | 1090@dideu.com | China | 8651 | 58 |
View Lastest Price from O-ACETYLSALICYLOYL CHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | O-Acetylsalicyloyl Chloride
5538-51-2
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2020-11-16 | O-Acetylsalicylryl chloride
5538-51-2
|
$10.00 | 1Kg/Bag | 99 | 999 | Longyan Tianhua Biological Technology Co., Ltd | |
 |
2020-02-17 | O-Acetylsalicylryl chloride
5538-51-2
|
$1.00 | 1KG | 98% HPLC | 10 tons | Career Henan Chemical Co |
-
- O-Acetylsalicyloyl Chloride
5538-51-2
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- O-Acetylsalicylryl chloride
5538-51-2
- $10.00
- 99
- Longyan Tianhua Biological Technology Co., Ltd
-
- O-Acetylsalicylryl chloride
5538-51-2
- $1.00
- 98% HPLC
- Career Henan Chemical Co
5538-51-2(O-ACETYLSALICYLOYL CHLORIDE)Related Search:
2-HYDROXYBENZOIC-3,4,5,6-D4 ACID
5-ACETYLSALICYLIC ACID
salicylacyl glucuronide
Acetylsalicylic Acid-d3
BENORILATE
Carbasalate calcium
4-HYDROXYBENZOIC-2,3,5,6-D4 ACID
Aspirin-acyl--D-glucuronide
4-Hydroxybenzoic-1,2,3,4,5,6-13C6 Acid
2-ACETOXYBENZOIC-3,4,5,6-D4 ACID
2-[[2-[[2-(Acetyloxy)benzoyl]oxy]benzoyl]oxy]benzoic Acid 2-[[2-[(2-carboxyphenoxy)carbonyl]phenoxy]carbonyl]phenyl Ester
1-[bis(4-fluorophenyl)methyl]-2,2,3,3,5,5,6,6-octadeuterio-4-[3-(3,4-dimethoxyphenyl)prop-2-enyl]piperazine
2-[[2-(Acetyloxy)benzoyl]oxy]benzoic Acid 2-[(2-Carboxyphenoxy)carbonyl]phenyl Ester
1of4
2-(acetyloxy)-benzoylchlorid
Acetylsalicoyl chloride
Benzoyl chloride, 2-(acetyloxy)-
O-Acetoxybenzoylchloride
o-Acetylsalicoyl chloride
ASPIRIN CHLORIDE
2-ACETOXYBENZOYL CHLORIDE
AKOS BBS-00003925
O-ACETYLSALICYLOYL CHLORIDE
O-Acetylsalicylryl chloride
O-Acetylsalicyloylchloride,98%
2-Acetoxybenzoic acid chloride
2-Acetyloxybenzoic acid chloride
2-ACETYLSALICYLOYL CHLORIDE
o-Acetylsalicychloride
O-Acetylsalicyloyl chloride 97%
2-(acetyloxy)-benzoyl chloride
Acetylsalicyloyl chloride,98%
O-ACETYLSALICYLOYL C
2-Acetoxybenzoyl chloride SynonyMs: Acetylsalicyloyl chloride
O-Acetylsalicyloyl Chloride
2-(Chlorocarbonyl)
O-acetylsalicylyl chloride
O-Acetylsalicyloyl Chloride >
Acetylsalicylic Acid Impurity 27
SKL1282
2-(carbonochloridoyl)phenyl acetate
2-(Chlorocarbonyl)phenyl acetate
ACETYLSALICYLOYL CHLORIDE
5538-51-2
2CH3CO2C6H4COCl
ACID CHLORIDE
Organic Building Blocks
Carbonyl Compounds
Building Blocks
Acid Halides
Acid Halides
Building Blocks
Carbonyl Compounds
Chemical Synthesis
Organic Building Blocks
Acid Halides
Carbonyl Compounds
Organic Building Blocks
