Eslicarbazepine
- CAS No.
- 104746-04-5
- Chemical Name:
- Eslicarbazepine
- Synonyms
- (S)-Licarbazepine;S-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN;(S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepin-5-carboxamide;(S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxaMide;(10S)-;Erelib;Pazzul;BIA 2-194;EC 810-248-9;Eslicarbazepine
- CBNumber:
- CB9500846
- Molecular Formula:
- C15H14N2O2
- Molecular Weight:
- 254.28
- MDL Number:
- MOL File:
- 104746-04-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 188-190°C |
|---|---|
| Boiling point | 431.3±55.0 °C(Predicted) |
| Density | 1.336 |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly, Heated), Methanol (Slightly), Pyridine (Slightly) |
| form | Solid |
| pka | 13.75±0.20(Predicted) |
| color | White to Pale Yellow |
| InChI | InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m0/s1 |
| InChIKey | BMPDWHIDQYTSHX-AWEZNQCLSA-N |
| SMILES | N1(C(N)=O)C2=CC=CC=C2[C@@H](O)CC2=CC=CC=C12 |
| FDA UNII | S5VXA428R4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
| REACH Registrations | Inactive |
Eslicarbazepine price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 35008 | Eslicarbazepine ≥95% | 104746-04-5 | 1mg | $40 | 2026-04-30 | Buy |
| Cayman Chemical | 35008 | Eslicarbazepine ≥95% | 104746-04-5 | 5mg | $179 | 2026-04-30 | Buy |
| Cayman Chemical | 35008 | Eslicarbazepine ≥95% | 104746-04-5 | 10mg | $315 | 2026-04-30 | Buy |
| Biosynth | FM26063 | (S)-10-Monohydroxy-10,11-dihydro carbamazepine | 104746-04-5 | 0.25g | $201.77 | 2026-06-04 | Buy |
| Biosynth | FM26063 | (S)-10-Monohydroxy-10,11-dihydro carbamazepine | 104746-04-5 | 0.5g | $302.67 | 2026-06-04 | Buy |
Eslicarbazepine Chemical Properties, Uses, Production
Description
Eslicarbazepine (also known as (S)-10-Monohydroxy-10,11-dihydro Carbamazepine) is a voltage-gated sodium channel (Nav) inhibitor and the active metabolite of the prodrug eslicarbazepine acetate. It enhances the slow activation of voltage-gated sodium channels, thereby reducing channel availability. Eslicarbazepine is an oral anticonvulsant used as an adjunctive treatment for partial-onset seizures.
Chemical Properties
Off-White Solid
Uses
An optically active metabolite of carbamazepine
Uses
A metabolite of Eslicarbazepine acetate, (BIA 2-093) a novel central nervous system drug.
Uses
(S)-10-Monohydroxy-10,11-dihydro Carbamazepine is the metabolite of Eslicarbazepine acetate, (BIA 2-093), (E659000) a novel central nervous system drug.
Definition
ChEBI: (S)-MHD is a dibenzooxazepine.
in vivo
Eslicarbazepine is an anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. Eslicarbazepine acetate is a prodrug for eslicarbazepine (S-licarbazepine), which is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel[1][2].
Eslicarbazepine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Forever Synthesis Co.,Ltd | 18096642264 18096642264 | sales01@foreversyn.com | China | 996 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9331 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
View Latest Price from Eslicarbazepine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-17 | Eslicarbazepine
104746-04-5
|
$40.00-123.00 | 99.97% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-06-30 | Eslicarbazepine
104746-04-5
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2019-08-27 | S-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN
104746-04-5
|
$1.00 | 1KG | 95%-99% | 1000kg | Career Henan Chemical Co |
-
- Eslicarbazepine
104746-04-5
- $40.00-123.00
- 99.97%
- TargetMol Chemicals Inc.
-
- Eslicarbazepine
104746-04-5
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- S-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN
104746-04-5
- $1.00
- 95%-99%
- Career Henan Chemical Co
