3,N4-ETHENOCYTOSINE
- CAS No.
- 55662-66-3
- Chemical Name:
- 3,N4-ETHENOCYTOSINE
- Synonyms
- 3,n(4)-ethanocytosine;imidazo[1,2-c]pyrimidin-5-ol;imidazo[1,2-f]pyrimidin-5-ol;IMidazo[1,2-c]pyriMidin-5(6H)-one
- CBNumber:
- CB9503443
- Molecular Formula:
- C6H5N3O
- Molecular Weight:
- 135.12
- MDL Number:
- MFCD00056907
- MOL File:
- 55662-66-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
3,N4-ETHENOCYTOSINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS114468 | Imidazo[1,2-c]pyrimidin-5(6H)-one 95% | 55662-66-3 | 1g | $198 | 2026-06-04 | Buy |
| Matrix Scientific | 296256 | Imidazo[1,2-c]pyrimidin-5(6H)-one | 55662-66-3 | 100.00mg | $32 | 2026-05-19 | Buy |
| Matrix Scientific | 296256 | Imidazo[1,2-c]pyrimidin-5(6H)-one | 55662-66-3 | 250.00mg | $54 | 2026-05-19 | Buy |
| Matrix Scientific | 296256 | Imidazo[1,2-c]pyrimidin-5(6H)-one | 55662-66-3 | 1.00g | $113 | 2026-05-19 | Buy |
| aablocks | AA00DIJ9 | Imidazo[1,2-c]pyrimidin-5(6H)-one 98% | 55662-66-3 | 100mg | $20 | 2026-05-28 | Buy |
3,N4-ETHENOCYTOSINE Chemical Properties, Uses, Production
Definition
ChEBI: 3,N(4)-ethenocytosine is an organic heterobicyclic compound. It has a role as a mutagen. It is functionally related to a cytosine. It derives from a hydride of an imidazo[1,2-c]pyrimidine.
Synthesis
107-20-0
71-30-7
55662-66-3
Procedure for the synthesis of imidazo[1,2-c]pyrimidin-5(6H)-one (13): 50% aqueous chloroacetaldehyde (0.686 mL, 5.40 mmol) was added to a stirred solution of 6-aminopyrimidin-2(1H)-one (500 mg, 4.50 mmol) in N,N-dimethylformamide (DMF, 10 mL). The reaction mixture was stirred at 70 °C for 16 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was washed with ethanol and ether to afford the target compound 13 as a light brown powder (320 mg, 53% yield). Thin layer chromatography (TLC) analysis showed Rf = 0.47 (unfolding agent: ethyl acetate/methanol, 4:1). The melting point of the product was 281-282 °C. Nuclear magnetic resonance hydrogen spectrum (1H NMR, 400 MHz, [D6]DMSO): δ = 6.62 (d, 1H, 3J = 7.6 Hz), 7.28 (d, 1H, 3J = 7.6 Hz), 7.41 (d, 1H, 3J = 1.2 Hz), 7.80 (d, 1H, 3J = 1.2 Hz), 11.6 (bs, 1H). Nuclear magnetic resonance carbon spectrum (13C NMR, 100 MHz, [D6]DMSO): δ = 97.7, 112.2, 129.4, 132.3, 145.9, 146.4. infrared spectrum (IR, KBr): ν = 3451, 3121, 3096, 1718, 1630, 1547, 1290, 1252, 1111 cm- 1. mass spectrum (ESI-MS): m/z 135.8 [M + H]+.
References
[1] Tetrahedron, 2014, vol. 71, # 1, p. 27 - 36
[2] Patent: WO2017/20944, 2017, A1. Location in patent: Page/Page column 16-17
3,N4-ETHENOCYTOSINE Preparation Products And Raw materials
3,N4-ETHENOCYTOSINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4534 | 58 |
| Nanjing XiZe Biotechnology CO., Ltd. | 025-66023220 15250997978 | 1511893459@qq.com | China | 4777 | 55 |
| Jiangsu aikang biomedical research and development co., LTD | 025-58859352 17714375163 | qzhang@aikonchem.com | China | 15525 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Birdo (Shanghai) Medical Technology Co., Ltd. | 021-58099077-8041 18601625411 | sales@birdotech.com | China | 9378 | 58 |
| Taizhou Nanfeng Pharmaceutical Research Institute | nanfengpharma@126.co 18616377689 | nanfengpharma@126.com | China | 20008 | 58 |
| Shanghai Sunmonth Technology Co., LTD | 15216675652 | xuanyuelj@163.com | China | 3000 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39796 | 58 |
