ChemicalBook >> CAS DataBase List >>2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl-

2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl-

2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl- structure

CAS No.: 1197033-22-9

Chemical Name:: 2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl-

Synonyms: S-cEt-T;cEt T Phosphoramidites;S-cEt-T phosphoramidite;S-cEt-T-CE-Phosphoramidite;CET-5-Me-U Phosphoramidite;5’-O-DMTr-cEt-5MeU phosphoramidite;5'-ODMTcEtm5UPhosphoramiditeAmidite;(S)-cEt-5-Me-U-3'-CE-phosphoramidite;5'-ODMT cEt m5U Phosphoramidite (Amidite);(1S,3R,4R,6S,7S)-7-[2-cyanoethoxy(diisopropylamino)phosphinoxy]-1-(4,4'-dimethoxytrityloxymethyl)-6-methyl-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane

CBNumber:: CB95891963

Molecular Formula:: C42H51N4O9P

Molecular Weight:: 786.86

MDL Number:

MOL File:: 1197033-22-9.mol

MSDS File:: SDS

Last updated:2026-05-28 05:05:49

Request For Quotation

2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl- Properties

pka	9.46±0.10(Predicted)
form	Solid
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	PO184594	5’-ODMT-cET-5-methyluridine 3’-OCE amidite	1197033-22-9	250mg	$515	2026-06-04	Buy
Biosynth	PO184594	5’-ODMT-cET-5-methyluridine 3’-OCE amidite	1197033-22-9	1000mg	$1040	2026-06-04	Buy
ChemScene	CS-0628992	5'-ODMT cEt m5U Phosphoramidite Amidite 99.76%	1197033-22-9	50mg	$70	2026-06-04	Buy
ChemScene	CS-0628992	5'-ODMT cEt m5U Phosphoramidite Amidite 99.76%	1197033-22-9	100mg	$119	2026-06-04	Buy
ChemScene	CS-0628992	5'-ODMT cEt m5U Phosphoramidite Amidite 99.76%	1197033-22-9	250mg	$238	2026-06-04	Buy

Product number	Packaging	Price	Buy
PO184594	250mg	$515	Buy
PO184594	1000mg	$1040	Buy
CS-0628992	50mg	$70	Buy
CS-0628992	100mg	$119	Buy
CS-0628992	250mg	$238	Buy

2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl- Chemical Properties, Uses, Production

Uses

5'-ODMT cEt m5U Phosphoramidite Amidite is a locked nucleic acid (LNA) analog. 5'-ODMT cEt m5U Phosphoramidite Amidite shows excellent safety and antisense activity in mice[1][2].

References

[1] Fiona J. Laraman, et al. Investigating the Activation Kinetics of Phosphoramidites for Oligonucleotide Synthesis. Org. Process Res. Dev. 2022, 26, 3, 764-772.
[2] Vasquez G, et al. Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839. DOI:10.1093/nar/gkab047

2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl- Suppliers

Global Suppliers ( 34)

Supplier	Tel	Email	Country	ProdList	Advantage
Hunan Hui Bai Shi Biotechnology Co., Ltd.	0731-85526065 13308475853	ivy@hnhbsj.com	China	7236	62
Wuhu Nuowei Chemical Technology Co., Ltd	0553-8233716 18055326116	sales@nuowei-chem.com	China	742	55
Hangzhou Dingyan Chem Co., LTD	0571-87157530-8002 15267169049	sales@dingyanchem.com	China	2611	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Wuhu Huaren Science and Technology Co., Ltd.	5842013 18155347026	xujuan@hdpharm.com	China	547	58
Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd.	19981275275	sales@zsdpharm.com	China	388	58
Dideu Industries Group Limited	+8617392712697	1022@dideu.com	China	29089	58
NewCan Biotech Limited	+86-571-86912261 19975279805	sales@newcanbio.com	China	9984	58
Wuhan Tangzhi Pharmaceutical Co., Ltd.	027-63498076 13658392159	sale@glycogene.com	China	838	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840	psaitong@jm-bio.com	China	27626	58

Supplier	Advantage
Hunan Hui Bai Shi Biotechnology Co., Ltd.	62
Wuhu Nuowei Chemical Technology Co., Ltd	55
Hangzhou Dingyan Chem Co., LTD	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Wuhu Huaren Science and Technology Co., Ltd.	58
Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd.	58
Dideu Industries Group Limited	58
NewCan Biotech Limited	58
Wuhan Tangzhi Pharmaceutical Co., Ltd.	58
Beijing Jin Ming Biotechnology Co., Ltd.	58

1197033-22-9 (2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl-) Related Search:

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2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl- S-cEt-T phosphoramidite CET-5-Me-U Phosphoramidite 2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-5-methyl- S-cEt-T 5'-ODMTcEtm5UPhosphoramiditeAmidite 5'-ODMT cEt m5U Phosphoramidite (Amidite) S-cEt-T-CE-Phosphoramidite cEt T Phosphoramidites 3-[({[(1S,3R,4R,6S,7S)-1-[(bis(4-methoxyphenyl)(phenyl)methoxy)methyl]-6-methyl-3-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl]oxy}(bis(propan-2-yl)amino)phosphanyl)oxy]propanenitrile (1S,3R,4R,6S,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-6-methyl-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite (1S,3R,4R,6S,7S)-7-[2-cyanoethoxy(diisopropylamino)phosphinoxy]-1-(4,4'-dimethoxytrityloxymethyl)-6-methyl-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane (S)-cEt-5-Me-U-3'-CE-phosphoramidite 5’-O-DMTr-cEt-5MeU phosphoramidite 3-[({[(1S,3R,4R,6S,7S)-1-[(bis(4-methoxyphenyl)(phenyl)methoxy)methyl]-6-methyl-3-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl]oxy}(bis(propan-2-yl)amino)ph 1197033-22-9 C42H51N4O9P Amidite