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5'-Fluoro-2'-hydroxypropiophenone

5'-Fluoro-2'-hydroxypropiophenone Structure
5'-Fluoro-2'-hydroxypropiophenone structure
CAS No.
443-09-4
Chemical Name:
5'-Fluoro-2'-hydroxypropiophenone
Synonyms
1-(5-FLUORO-2-HYDROXYPHENYL)PROPAN-1-ONE;1-(5-Fluoro-2-hydroxyphenyl);2-hydroxy-5-fluoropropiophenone;5'-Fluoro-2'-hydroxypropiophenone;1-(5-Fluoro-2-hydroxyphenyl)-1-propanone;1-Propanone,1-(5-fluoro-2-hydroxyphenyl)-;5′-Fluoro-2′-hydroxypropiophenone, CAS 443-09-4;JRH-01109, 1-(5-Fluoro-2-hydroxyphenyl)propan-1-one, 97%
CBNumber:
CB9678983
Molecular Formula:
C9H9FO2
Molecular Weight:
168.16
MDL Number:
MFCD00218583
MOL File:
443-09-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:56:33
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5'-Fluoro-2'-hydroxypropiophenone Properties

Melting point 35-39 °C
Boiling point 117-121 °C(Press: 22 Torr)
Density 1.200±0.06 g/cm3(Predicted)
Flash point 219 °F
pka 8.26±0.48(Predicted)
form solid
InChI 1S/C9H9FO2/c1-2-8(11)7-5-6(10)3-4-9(7)12/h3-5,12H,2H2,1H3
InChIKey OLVYYKLFIUGMCW-UHFFFAOYSA-N
SMILES CCC(=O)c1cc(F)ccc1O
CAS DataBase Reference 443-09-4(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P261-P280-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22-37/38-41
Safety Statements  26-39
WGK Germany  3
Hazard Note  Irritant
HS Code  2914790090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3

5'-Fluoro-2'-hydroxypropiophenone price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 663697 5′-Fluoro-2′-hydroxypropiophenone 97% 443-09-4 1g $63.6 2023-01-07 Buy
Sigma-Aldrich 663697 5′-Fluoro-2′-hydroxypropiophenone 97% 443-09-4 10g $250 2022-05-15 Buy
Usbiological 280045 2'-Hydroxy-5'-fluoropropiophenone Asreported 443-09-4 1g $337 2026-06-03 Buy
Usbiological 280045 2'-Hydroxy-5'-fluoropropiophenone Asreported 443-09-4 2g $460 2026-06-03 Buy
Usbiological 280045 2'-Hydroxy-5'-fluoropropiophenone Asreported 443-09-4 5g $726 2026-06-03 Buy
Product number Packaging Price Buy
663697 1g $63.6 Buy
663697 10g $250 Buy
280045 1g $337 Buy
280045 2g $460 Buy
280045 5g $726 Buy

5'-Fluoro-2'-hydroxypropiophenone Chemical Properties, Uses, Production

Preparation

Preparation by Fries rearrangement of p-fluorophenyl propionate (b.p.18–20 118–120°) with aluminium chloride at 150° for 1 h (80–81%) or at reflux for 30 min (57%)
Also obtained by demethylation of 5-fluoro-2-methoxy-propiophenone (b.p.13 132°) with refluxing pyridinium chloride for 15 min (76%).

5'-Fluoro-2'-hydroxypropiophenone Preparation Products And Raw materials

Raw materials

Preparation Products

5'-Fluoro-2'-hydroxypropiophenone Suppliers

Global Suppliers ( 66)
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Changzhou Anxuan Chemical, Co., Ltd. 13912302692 sales@anxuanchem.com China 4824 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Wuxi AppTec 022-59987777 13552403979 jia_guoqiang@wuxiapptec.com China 22344 58
Aikon International Limited 025-66113011 19370895928 qzhang@aikonchem.com China 15390 58
Shanghai SPAR pharmaceutical technology co., LTD 021-000000 admin@jingshipharmatech.com China 9919 58
Fuxin Crest Biotechnology Co. Ltd. 13062833949 fred.wen@crcorporation.cn China 853 58
Supplier Advantage
Energy Chemical 61
Cool Pharm, Ltd 58
Sigma-Aldrich 80
Changzhou Anxuan Chemical, Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Wuxi AppTec 58
Aikon International Limited 58
Shanghai SPAR pharmaceutical technology co., LTD 58
Fuxin Crest Biotechnology Co. Ltd. 58

View Latest Price from 5'-Fluoro-2'-hydroxypropiophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-FLUORO-2-HYDROXYPROPIOPHENONE pictures 2026-08-07 5-FLUORO-2-HYDROXYPROPIOPHENONE
443-09-4
 $1.00-100.00 1KG 99% 300KG Shaanxi Dideu Medichem Co. Ltd

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2-hydroxy-5-fluoropropiophenone 1-(5-Fluoro-2-hydroxyphenyl) JRH-01109, 1-(5-Fluoro-2-hydroxyphenyl)propan-1-one, 97% 1-Propanone,1-(5-fluoro-2-hydroxyphenyl)- 1-(5-Fluoro-2-hydroxyphenyl)-1-propanone 5′-Fluoro-2′-hydroxypropiophenone, CAS 443-09-4 1-(5-FLUORO-2-HYDROXYPHENYL)PROPAN-1-ONE 5'-Fluoro-2'-hydroxypropiophenone 443-09-4