5-(Trimethylsilyl)-4-pentyn-1-ol
- CAS No.
- 13224-84-5
- Chemical Name:
- 5-(Trimethylsilyl)-4-pentyn-1-ol
- Synonyms
- 5-(triMethylsilyl)pent-4-yn-1-ol;TIMTEC-BB SBB009060;TriMethylsilyl-4-prnty;5-Trimethylsilyl-4-prntyn-1-ol;5-(Trimethylsilyl)-4-pentyn-1-ol;4-Pentyn-1-ol,5-(trimethylsilyl)-;5-Trimethylsilyl-4-pentyn-1-ol,97%;5-(Trimethylsilyl)-4-pentyn-1-ol 96%;5-(TRIMETHYLSILYL)-4-PENTYN-1-OL, 98%5-(TRIMETHYLSILYL)-4-PENTYN-1-OL, 98%5-(TRIMETHYLSILYL)-4-PENTYN-1-OL, 98%
- CBNumber:
- CB9723513
- Molecular Formula:
- C8H16OSi
- Molecular Weight:
- 156.3
- MDL Number:
- MFCD00190229
- MOL File:
- 13224-84-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 76 °C/15 mmHg (lit.) |
|---|---|
| Density | 0.861 g/mL at 25 °C |
| refractive index |
n |
| Flash point | 184 °F |
| storage temp. | Sealed in dry,2-8°C |
| pka | 14.97±0.10(Predicted) |
| Specific Gravity | 0.852 |
| Appearance | Colorless to light yellow Liquid |
| InChI | 1S/C8H16OSi/c1-10(2,3)8-6-4-5-7-9/h9H,4-5,7H2,1-3H3 |
| InChIKey | LIHAMNSEAAPIRM-UHFFFAOYSA-N |
| SMILES | C[Si](C)(C)C#CCCCO |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227-H315-H319-H335 | |||||||||
| Precautionary statements | P210e-P261-P280a-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) | |||||||||
| Risk Statements | 10 | |||||||||
| Safety Statements | 16 | |||||||||
| RIDADR | 1987 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29310099 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
5-(Trimethylsilyl)-4-pentyn-1-ol price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 650315 | 5-(Trimethylsilyl)-4-pentyn-1-ol 96% | 13224-84-5 | 5g | $97.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 650315 | 5-(Trimethylsilyl)-4-pentyn-1-ol 96% | 13224-84-5 | 25g | $349 | 2026-04-30 | Buy |
| Synthonix | T47165 | 5-(Trimethylsilyl)pent-4-yn-1-ol 95% | 13224-84-5 | 1g | $80 | 2026-05-06 | Buy |
| Synthonix | T47165 | 5-(Trimethylsilyl)pent-4-yn-1-ol 95% | 13224-84-5 | 5g | $90 | 2026-05-06 | Buy |
| Synthonix | T47165 | 5-(Trimethylsilyl)pent-4-yn-1-ol 95% | 13224-84-5 | 10g | $170 | 2026-05-06 | Buy |
5-(Trimethylsilyl)-4-pentyn-1-ol Chemical Properties, Uses, Production
Chemical Properties
Clear colorless to yellow liquid
Synthesis
75-77-4
5390-04-5
13224-84-5
To a solution of 4-pentyn-1-ol (5.9 g, 70 mmol, 1.0 eq.) in THF (100 mL) was slowly added n-butyllithium (2.50 M hexane solution, 60.0 mL, 147 mmol, 2.10 eq.) dropwise at -78 °C. The reaction mixture was slowly warmed to room temperature and then cooled again to -78°C. Subsequently, freshly distilled trimethylchlorosilane (20.0 mL, 154 mmol, 2.20 eq.) was added dropwise to the mixture and slowly warmed to room temperature. The reaction was kept stirred for 2 hours. After completion of the reaction, the reaction was quenched with 3M HCl aqueous solution and the resulting biphasic system was stirred vigorously for 3 hours. The aqueous layer was separated, extracted twice with ether (Et2O), the organic phases were combined, washed with saturated brine, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated to quantitatively obtain 5-(trimethylsilyl)-4-pentyn-1-ol.
References
[1] Angewandte Chemie - International Edition, 2013, vol. 52, # 2, p. 739 - 743
[2] Angew. Chem., 2013, vol. 125, # 2, p. 767 - 771,5
[3] Arkivoc, 2014, vol. 2014, # 3, p. 287 - 296
[4] Advanced Synthesis and Catalysis, 2014, vol. 356, # 9, p. 2051 - 2060
[5] Chemistry - A European Journal, 2013, vol. 19, # 38, p. 12649 - 12652
5-(Trimethylsilyl)-4-pentyn-1-ol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
View Latest Price from 5-(Trimethylsilyl)-4-pentyn-1-ol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-08 | 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
13224-84-5
|
$1.00 | 1KG | 98%HPLC | 10 tons/month | Career Henan Chemical Co |
-
- 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
13224-84-5
- $1.00
- 98%HPLC
- Career Henan Chemical Co
