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2-Phenylindole

2-Phenylindole Structure
2-Phenylindole structure
CAS No.
948-65-2
Chemical Name:
2-Phenylindole
Synonyms
2-PHENYL-1H-INDOLE;1H-Indole,2-phenyl-;NSC 15776;stabilizeri;Stabilizer I;-Phenylindole;A-PHENYLINDOL;2-PHENYLINDOLE;a-Phenylindole;2-phenyl-indol
CBNumber:
CB9725557
Molecular Formula:
C14H11N
Molecular Weight:
193.24
MDL Number:
MFCD00005608
MOL File:
948-65-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:55:06
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2-Phenylindole Properties

Melting point 188-190 °C (lit.)
Boiling point 250 °C/10 mmHg (lit.)
Density 1.1061 (rough estimate)
refractive index 1.5850 (estimate)
Flash point 250°C/10mm
storage temp. Sealed in dry,Room Temperature
solubility almost transparency in Methanol
form Powder
pka 16.80±0.30(Predicted)
color Off-white to beige or slightly green
InChI 1S/C14H11N/c1-2-6-11(7-3-1)14-10-12-8-4-5-9-13(12)15-14/h1-10,15H
InChIKey KLLLJCACIRKBDT-UHFFFAOYSA-N
SMILES c1ccc(cc1)-c2cc3ccccc3[nH]2
CAS DataBase Reference 948-65-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII MQD44HV3P1
NIST Chemistry Reference 1H-Indole, 2-phenyl-(948-65-2)
EPA Substance Registry System 1H-Indole, 2-phenyl- (948-65-2)
UNSPSC Code 41116107
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H318-H335-H413
Precautionary statements  P273-P280-P302+P352-P305+P351+P338+P310
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  37/38-41
Safety Statements  26-39
WGK Germany  3
RTECS  NM1272500
TSCA  TSCA listed
HS Code  29309090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Dam. 1
Skin Irrit. 2
STOT SE 3
NFPA 704
1 0

2-Phenylindole price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P26600 2-Phenylindole technical grade, 95% 948-65-2 5g $40 2026-04-30 Buy
Sigma-Aldrich P26600 2-Phenylindole technical grade, 95% 948-65-2 100g $49.2 2026-04-30 Buy
Sigma-Aldrich 96607 2-Phenylindole analytical standard 948-65-2 100 mg $68.9 2026-04-30 Buy
TCI Chemical P0188 2-Phenylindole >98.0%(GC) 948-65-2 25g $24 2026-04-30 Buy
TCI Chemical P0188 2-Phenylindole >98.0%(GC) 948-65-2 250g $70 2026-04-30 Buy
Product number Packaging Price Buy
P26600 5g $40 Buy
P26600 100g $49.2 Buy
96607 100 mg $68.9 Buy
P0188 25g $24 Buy
P0188 250g $70 Buy

2-Phenylindole Chemical Properties, Uses, Production

Chemical Properties

off-white to beige or slightly green powder

Uses

Reactant for preparation of: • ;Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition1• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Organic light emitting diodes (OLEDs)3• ;Anti inflammatory agents4• ;Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors5• ;Agents for cancer and malaria therapy6• ;Antifungal and antibacterial agents7• ;Fluorescent probes8Reactant in:• ;Difluorohydroxylation reactions†• ;Mannich-type reactions†

Uses

Phenylindole is a stabilizer in PVC-plastic products (α-phenylindole).

Uses

Reactant for preparation of:

  • Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition
  • Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Organic light emitting diodes (OLEDs)
  • Anti inflammatory agents
  • Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors
  • Agents for cancer and malaria therapy
  • Antifungal and antibacterial agents
  • Fluorescent probes

Reactant in:
  • Difluorohydroxylation reactions
  • Mannich-type reactions

Preparation

2-phenylindole is prepared by condensing phenylhydrazine and acetophenone, and then closing the ring in the presence of zinc chloride. or it can be prepared by heating bromoacetophenone with excess aniline, or heating N-(2-methylphenyl)benzamide and sodium ethoxide at 360-380℃ in isolation from air.

Definition

ChEBI: 2-phenyl-1H-indole is a phenylindole.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 1459, 1992 DOI: 10.1016/S0040-4039(00)91646-0
Journal of Heterocyclic Chemistry, 29, p. 1085, 1992 DOI: 10.1002/jhet.5570290509

2-Phenylindole synthesis

98-86-2
100-63-0
948-65-2
Synthesis of 2-Phenylindole from Acetophenone and Phenylhydrazine

2-Phenylindole Preparation Products And Raw materials

Raw materials

Ethanol Biphenyl Acetone Acetophenone 2-Bromoacetophenone
polyphosphoric acid Benzamide Acetic acid Phenylhydrazine 1-Propanone, 2,2-dimethyl-1-(2-phenyl-1H-indol-1-yl)-
N-[2-(cyanomethyl)phenyl]acetamide 2-(2-nitrophenyl)-1-phenylethanone 1-nitro-2-(2-phenylethenyl)benzene (E)-2-Nitrostilbene 2-phenylindoline
AcetaMide, 2,2,2-trifluoro-N-(2-iodophenyl)- 1-Bromo-2-phenylethynyl-benzene Phenylpropiolic acid

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Preparation Products

3-[(2,4-dihydro-2,4-dimethyl-3H-1,2,4-triazol-3-ylidene)hydrazono]-1-methyl-2-phenyl-3H-indolium chloride Acid red 351

2-Phenylindole Suppliers

Global Suppliers ( 355)
Supplier Tel Email Country ProdList Advantage
Qingdao Gelisi Pharmaceutical Co. , Ltd 189-4623-7973 13375559818 cfy69@163.com China 131 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Qingdao Gelisi Pharmaceutical Co. , Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
future industrial shanghai co., ltd 65
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing dtftchem Technology Co., Ltd. 62
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61

View Latest Price from 2-Phenylindole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Phenylindole pictures 2026-09-16 2-Phenylindole
948-65-2
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
2-Phenylindole pictures 2026-08-20 2-Phenylindole
948-65-2
 $1.10 1g 99.0% Min 100 Tons Dideu Industries Group Limited
2-Phenylindole pictures 2026-05-28 2-Phenylindole
948-65-2
 $2.00-5.00 1kg 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
  • 2-Phenylindole pictures
  • 2-Phenylindole
    948-65-2
  • $2.00-5.00
  • 99%
  • Hebei Chuanghai Biotechnology Co,.LTD

2-Phenylindole Spectrum

2-Phenylindole(948-65-2)MS2-Phenylindole(948-65-2)1HNMR2-Phenylindole(948-65-2)13CNMR2-Phenylindole(948-65-2)IR12-Phenylindole(948-65-2)IR22-Phenylindole(948-65-2)Raman

948-65-2 (2-Phenylindole) Related Search:

Indometacin Indole-3-acetic acid 2-Methylindole Indole-3-butyric acid 1-Phenyl-2-nitropropene
1-Phenyl-2-propanol N-Methyl-2-Phenylindole-3-Carboxaldehyde,1-METHYL-2-PHENYLINDOLE-3-CARBOXALDEHYDE,3-FORMYL-1-METHYL-2-PHENYLINDOLE,1-METHYL-2-PHENYLINDOLE-3-CARBOXYALDEHYDE 1-ETHYL-2-PHENYLINDOLE,N-ETHYL-2-PHENYLINDOLE BASIC RED 29 Phenylacetone
SODIUM 2-PHENYLINDOLE-5-SULFONATE,2-phenylindole-5-sulfonicacidsodiumsal 4',6-Diamidino-2-phenylindole dihydrochloride 3-(4-Fluorophenyl)-1-isopropyl-1H-indole 1-Methyl-2-phenylindole 5-Methyl-2-phenylindole
2-(4-Chlorophenyl)indole 5,6-Methylenedioxy-2-phenylindole 1-Phenyloxindole

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1H-Indole,2-phenyl- 2-phenyl-1h-indol 2-phenyl-indol a-Phenylindole 2-Phenylindole ,99% NSC 15776 2-Phenylindole technical grade, 95% PHENYLINDOL,ALPHA- 2-PHENYLINDOLE 2-PHENYLINDOLE, TECH., 95% 2-Phenylindole,95% alpha-Phenylindole Indole, 2-phenyl- -Phenylindole Stabilizer I stabilizeri ALPHA-PHENYLINDOL A-PHENYLINDOL 2-Phenylindole ISO 9001：2015 REACH Compound PDK0415 2-Phenylindoie 2-PHENYL-1H-INDOLE 948-65-2 C6H5C8H6N C14H10KN Indoles Simple Indoles Heterocyclic Building Blocks Building Blocks Pyridines Building Blocks Heterocyclic Building Blocks intermediates Heterocycle-Indole series Building Blocks C13 to C27 Chemical Synthesis Heterocyclic Building Blocks Indoles Simple Indoles Heterocyclic Compounds Indole