Cyclohexyl chloroformate
- CAS No.
- 13248-54-9
- Chemical Name:
- Cyclohexyl chloroformate
- Synonyms
- AT-51099;cyclohcxyl chlrorformate;CYCLOHEXYL CHLOROFORMATE;cyclohexyl chloromethanoate;Cyclohexyl carbonochloridate;chloroformic acid cyclohexyl ester;carbonochloridicacid,cyclohexylester
- CBNumber:
- CB9766031
- Molecular Formula:
- C7H11ClO2
- Molecular Weight:
- 162.61
- MDL Number:
- MFCD00035802
- MOL File:
- 13248-54-9.mol
- MSDS File:
- SDS
| Boiling point | 87.5℃ |
|---|---|
| Density | 1.14±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Colourless |
| CAS DataBase Reference | 13248-54-9(CAS DataBase Reference) |
| FDA UNII | CFS37667DP |
| EPA Substance Registry System | Carbonochloridic acid, cyclohexyl ester (13248-54-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Risk Statements | 23/24/25-34 |
| Safety Statements | 26-36/37/39 |
| RIDADR | 3277 |
Cyclohexyl chloroformate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C987325 | CyclohexylChloroformate | 13248-54-9 | 1g | $1060 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0025726 | CYCLOHEXYL CHLOROFORMATE 95.00% | 13248-54-9 | 100G | $2868.16 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC145349 | Cyclohexyl chloroformate | 13248-54-9 | 100mg | $400 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC145349 | Cyclohexyl chloroformate | 13248-54-9 | 250mg | $450 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC145349 | Cyclohexyl chloroformate | 13248-54-9 | 500mg | $500 | 2021-12-16 | Buy |
Cyclohexyl chloroformate Chemical Properties,Uses,Production
Chemical Properties
transparency liquid
Uses
Cyclohexyl Chloroformate acts as a protecting group for amines and indoles in peptide synthesis.
Synthesis
The Preparative Method of Cyclohexyl Chloroformate: a 1 L round-bottomed flask equipped with a delivery tube extending to the bottom of the flask, a pressure-equalizing addition funnel and a cold-finger condenser cooled with dry ice-acetone were placed in an ice bath. The exit tube of the condenser was connected to a CaCl2 drying tube and a suitable trap for phosgene and HCl. Phosgene was introduced into the flask until 109 g (1.1 mol) had been condensed. The reaction flask was stirred while 100 g (1 mol) of cyclohexyl alcohol was added through the dropping funnel at a rate to keep the mixture in gentle reflux for 1 h. The flask was allowed to stand at room temperature with stirring for 2 h. The solution was then concentrated under reduced pressure at room temperature to remove HCl and the excess phosgene. The residue may be used without further purification.
Precautions
When stored for a prolonged period, it decomposes to CO2 and cyclohexyl chloride. Store in a refrigerator. Bottles may develop pressure and should be cooled before opening. Use in a fume hood. It is irritating to skin, eyes, and mucous membranes.
References
1. Fourneau, M. E.; Montaigne, M.; Puyal, J., J. Anales Soc. Espanol Fis. Quim. 1920, 73, 323.
2. McKay, F. C.; Albertson, N. F., J. Am. Chem. Soc. 1957, 79, 4686.
3. Sakakibara, S.; Shimonishi, Y.; Kishida, Y.; Okada, M.; Sugihara, H., Bull. Chem. Soc. Jpn 1967, 40, 2164.
4. Nishiuchi, Y.; Nishio, H.; Inui, T.; Kimura, T.; Sakakibara, S., Tetrahedron Lett. 1996, 37, 7529.
5. Mez, G.; Mihala, N.; Kóczán, G.; Hudecz, F., Tetrahedron 1998, 54, 6757.
Cyclohexyl chloroformate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Shanghai Yudiao Chemistry Technology Co.,Ltd | 02137285211 18964703211 | info@yudiaochem.com | CHINA | 238 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20342 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 19957148339; | market18@leapchem.com | China | 24727 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
View Lastest Price from Cyclohexyl chloroformate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Cyclohexyl chloroformate
13248-54-9
|
US $1.00 / kg | 1kg | 99% | Customized | Career Henan Chemical Co |
-
- Cyclohexyl chloroformate
13248-54-9
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
