Cyclohexyl chloroformate
- CAS No.
- 13248-54-9
- Chemical Name:
- Cyclohexyl chloroformate
- Synonyms
- Cyclohexyl carbonochloridate;AT-51099;cyclohcxyl chlrorformate;CYCLOHEXYL CHLOROFORMATE;cyclohexyl chloromethanoate;chloroformic acid cyclohexyl ester;carbonochloridicacid,cyclohexylester
- CBNumber:
- CB9766031
- Molecular Formula:
- C7H11ClO2
- Molecular Weight:
- 162.61
- MDL Number:
- MFCD00035802
- MOL File:
- 13248-54-9.mol
- MSDS File:
- SDS
| Boiling point | 87.5℃ |
|---|---|
| Density | 1.14±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Colourless |
| CAS DataBase Reference | 13248-54-9(CAS DataBase Reference) |
| FDA UNII | CFS37667DP |
| EPA Substance Registry System | Carbonochloridic acid, cyclohexyl ester (13248-54-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Risk Statements | 23/24/25-34 |
| Safety Statements | 26-36/37/39 |
| RIDADR | 3277 |
| TSCA | TSCA listed |
Cyclohexyl chloroformate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FC145349 | Cyclohexyl chloroformate | 13248-54-9 | 50mg | $900 | 2026-06-04 | Buy |
| Biosynth | FC145349 | Cyclohexyl chloroformate | 13248-54-9 | 25mg | $900 | 2026-06-04 | Buy |
| Biosynth | FC145349 | Cyclohexyl chloroformate | 13248-54-9 | 250mg | $900 | 2026-06-04 | Buy |
| Biosynth | FC145349 | Cyclohexyl chloroformate | 13248-54-9 | 10mg | $900 | 2026-06-04 | Buy |
| Biosynth | FC145349 | Cyclohexyl chloroformate | 13248-54-9 | 100mg | $900 | 2026-06-04 | Buy |
Cyclohexyl chloroformate Chemical Properties, Uses, Production
Chemical Properties
transparency liquid
Uses
Cyclohexyl Chloroformate acts as a protecting group for amines and indoles in peptide synthesis.
Synthesis
The Preparative Method of Cyclohexyl Chloroformate: a 1 L round-bottomed flask equipped with a delivery tube extending to the bottom of the flask, a pressure-equalizing addition funnel and a cold-finger condenser cooled with dry ice-acetone were placed in an ice bath. The exit tube of the condenser was connected to a CaCl2 drying tube and a suitable trap for phosgene and HCl. Phosgene was introduced into the flask until 109 g (1.1 mol) had been condensed. The reaction flask was stirred while 100 g (1 mol) of cyclohexyl alcohol was added through the dropping funnel at a rate to keep the mixture in gentle reflux for 1 h. The flask was allowed to stand at room temperature with stirring for 2 h. The solution was then concentrated under reduced pressure at room temperature to remove HCl and the excess phosgene. The residue may be used without further purification.
Precautions
When stored for a prolonged period, it decomposes to CO2 and cyclohexyl chloride. Store in a refrigerator. Bottles may develop pressure and should be cooled before opening. Use in a fume hood. It is irritating to skin, eyes, and mucous membranes.
References
1. Fourneau, M. E.; Montaigne, M.; Puyal, J., J. Anales Soc. Espanol Fis. Quim. 1920, 73, 323.
2. McKay, F. C.; Albertson, N. F., J. Am. Chem. Soc. 1957, 79, 4686.
3. Sakakibara, S.; Shimonishi, Y.; Kishida, Y.; Okada, M.; Sugihara, H., Bull. Chem. Soc. Jpn 1967, 40, 2164.
4. Nishiuchi, Y.; Nishio, H.; Inui, T.; Kimura, T.; Sakakibara, S., Tetrahedron Lett. 1996, 37, 7529.
5. Mez, G.; Mihala, N.; Kóczán, G.; Hudecz, F., Tetrahedron 1998, 54, 6757.
Cyclohexyl chloroformate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6744 | 52 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Xunteng International Trading Co.,Limited | China Hong Kong | 876 | 55 | ||
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| RiZhao LiDeShi Chemical Co., Ltd. | 010-51268198 | leadershipchem@126.com | China | 2541 | 58 |
| Mei Lan Industrial (Shanghai) Co., Ltd. | 021-58958189 | wouchina@126.com | China | 2658 | 55 |
View Latest Price from Cyclohexyl chloroformate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Cyclohexyl chloroformate
13248-54-9
|
$1.00 | 1kg | 99% | Career Henan Chemical Co |
-
- Cyclohexyl chloroformate
13248-54-9
- $1.00
- 99%
- Career Henan Chemical Co
13248-54-9 (Cyclohexyl chloroformate) Related Search:
1of4
