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Methyl 4-methoxy-1H-indazole-3-carboxylate

CAS No.
865887-07-6
Chemical Name:
Methyl 4-methoxy-1H-indazole-3-carboxylate
Synonyms
Methyl 4-methoxy-1H-indazole-3-carboxylate;Methyl-4-benzyloxy-1H-indazole-3-carboxylate;1H-Indazole-3-carboxylic acid, 4-Methoxy-, Methyl ester
CBNumber:
CB9770133
Molecular Formula:
C10H10N2O3
Molecular Weight:
206.2
MDL Number:
MFCD07371614
MOL File:
865887-07-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:56:35

Methyl 4-methoxy-1H-indazole-3-carboxylate Properties

storage temp. 2-8°C
Appearance Off-white to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Methyl 4-methoxy-1H-indazole-3-carboxylate price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 296111 Methyl 4-methoxy-1H-indazole-3-carboxylate 865887-07-6 50.00mg $112 2026-05-19 Buy
Matrix Scientific 296111 Methyl 4-methoxy-1H-indazole-3-carboxylate 865887-07-6 100.00mg $186 2026-05-19 Buy
Matrix Scientific 296111 Methyl 4-methoxy-1H-indazole-3-carboxylate 865887-07-6 250.00mg $239 2026-05-19 Buy
aablocks AA004LBX Methyl 4-methoxy-1H-indazole-3-carboxylate 95% 865887-07-6 50mg $78 2026-05-28 Buy
aablocks AA004LBX Methyl 4-methoxy-1H-indazole-3-carboxylate 95% 865887-07-6 100mg $131 2026-05-28 Buy
Product number Packaging Price Buy
296111 50.00mg $112 Buy
296111 100.00mg $186 Buy
296111 250.00mg $239 Buy
AA004LBX 50mg $78 Buy
AA004LBX 100mg $131 Buy

Methyl 4-methoxy-1H-indazole-3-carboxylate Chemical Properties, Uses, Production

Synthesis

Methanol

67-56-1

4-Methoxyindazole-3-carboxylic acid

865887-02-1

METHYL 4-METHOXY-1H-INDAZOLE-3-CARBOXYLATE

865887-07-6

Acetyl chloride (18 mL) was slowly added dropwise to methanol (180 mL) at 0 °C and the reaction mixture was kept stirred at this temperature for 1 hour. Subsequently, 4-methoxy-1H-indazole-3-carboxylic acid (21.8 mmol) was added and the reaction mixture was heated to reflux for 3 hours. After completion of the reaction, the solution was concentrated to dryness under reduced pressure. The resulting residue was suspended in water and the pH was adjusted with saturated sodium bicarbonate solution to 7. Next, extraction was carried out with ethyl acetate (3 x 100 mL), the organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Finally, the crude product was purified by column chromatography (eluent ratio of 2:1 petroleum ether/ethyl acetate) to afford methyl 4-methoxy-1H-indazole-3-carboxylate in 5% yield (two-step reaction) and the product was a yellow solid.

References

[1] Patent: US2007/78147, 2007, A1. Location in patent: Page/Page column 67

Methyl 4-methoxy-1H-indazole-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 4-methoxy-1H-indazole-3-carboxylate Spectrum

Methyl-4-benzyloxy-1H-indazole-3-carboxylate 1H-Indazole-3-carboxylic acid, 4-Methoxy-, Methyl ester Methyl 4-methoxy-1H-indazole-3-carboxylate 865887-07-6