2-[[4-(2-Methoxyphenyl)piperazin-1-yl] methyl]-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one
![2-[[4-(2-Methoxyphenyl)piperazin-1-yl] methyl]-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one Structure](StructureFile/ChemBookStructure3/GIF/CB9771332.gif)
- CAS No.
- 149847-77-8
- Chemical Name:
- 2-[[4-(2-Methoxyphenyl)piperazin-1-yl] methyl]-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one
- Synonyms
- 2-MPMDQ;2-[[4-(2-Methoxyphenyl)piperazin-1-yl] methyl]-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one;2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-6-methyl-2,6-dihydroimidazo[1,2-c]quinazolin-5(3H)-one;Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-
- CBNumber:
- CB9771332
- Molecular Formula:
- C23H27N5O2
- Molecular Weight:
- 405.49
- MDL Number:
- MFCD00673888
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
2-[[4-(2-Methoxyphenyl)piperazin-1-yl] methyl]-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 418892 | 2-MPMDQ | 149847-77-8 | 1mg | $355 | 2026-06-03 | Buy |
| Usbiological | 418892 | 2-MPMDQ | 149847-77-8 | 2.5mg | $566 | 2026-06-03 | Buy |
| Usbiological | 254368 | 2-MPMDQ Asreported | 149847-77-8 | 10mg | $430 | 2026-06-03 | Buy |
| Usbiological | 254368 | 2-MPMDQ Asreported | 149847-77-8 | 50mg | $1210 | 2026-06-03 | Buy |
| ApexBio Technology | B6397 | 2-MPMDQ | 149847-77-8 | 10mg | $246 | 2026-05-06 | Buy |
2-[[4-(2-Methoxyphenyl)piperazin-1-yl] methyl]-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one Chemical Properties, Uses, Production
Uses
2-MPMDQ is a novel class of α1-adrenoceptor antagonists and acts as an anti-hypertensive agent.
Definition
ChEBI: 2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5-one is a member of piperazines.
Biological Activity
Potent and selective α 1 -adrenoceptor antagonist; hypotensive.
IC 50
α1-adrenergic receptor: 0.37 nM (Ki); α2-adrenergic receptor: 1740 nM (Ki)
References
[1]. chern jw, tao pl, yen mh, et al. studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents. j med chem, 1993, 36(15): 2196-2207.
2-[[4-(2-Methoxyphenyl)piperazin-1-yl] methyl]-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
2-[[4-(2-Methoxyphenyl)piperazin-1-yl] methyl]-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| Shanghai Easy CDMO Co.,Ltd | Info@easycdmo.com 13564957716 | Info@easycdmo.com | China | 9999 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +86-18327326525 | masar@topule.com | China | 8433 | 58 |
