Difurfuryldisulfide
- CAS No.
- 4437-20-1
- Chemical Name:
- Difurfuryldisulfide
- Synonyms
- DIFURFURYL DISULFIDE;FURFURYL DISULFIDE;DIFURFURYL DISULPHIDE;1,2-Bis(furan-2-ylmethyl)disulfane;FEMA 3146;DifurfuryL;2,2'-(Dithiodimethylene)difuran;2-(Furan-2-ylmethyldisulfanylmethyl)furan;Difuryl disulfide;Difurfuryldisulfid
- CBNumber:
- CB9771367
- Molecular Formula:
- C10H10O2S2
- Molecular Weight:
- 226.32
- MDL Number:
- MFCD00010082
- MOL File:
- 4437-20-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 10-11 °C (lit.) |
|---|---|
| Boiling point | 112-115 °C/0.5 mmHg (lit.) |
| Density | 1.233 g/mL at 25 °C (lit.) |
| refractive index |
n |
| FEMA | 3146 | 2,2'-(DITHIODIMETHYLENE)-DIFURAN |
| FLAVIS Number | 13.050 | Difurfuryl disulfide |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| form | clear liquid |
| color | Colorless to Yellow |
| Specific Gravity | 1.235 (20/4℃) |
| Odor | at 0.01 % in propylene glycol. sulfury coffee roasted chicken meaty onion cabbage |
| Odor Type | coffee |
| biological source | synthetic |
| JECFA Number | 1081 |
| Major Application | flavors and fragrances |
| InChI | 1S/C10H10O2S2/c1-3-9(11-5-1)7-13-14-8-10-4-2-6-12-10/h1-6H,7-8H2 |
| InChIKey | CBJPZHSWLMJQRI-UHFFFAOYSA-N |
| SMILES | C(SSCc1ccco1)c2ccco2 |
| LogP | 4.03 |
| CAS DataBase Reference | 4437-20-1(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | 2,2'-(DITHIODIMETHYLENE) DIFURAN |
| EWG's Food Scores | 1 |
| FDA UNII | 5IP6729ULF |
| NIST Chemistry Reference | Bis(2-furfuryl)disulfide(4437-20-1) |
| EPA Substance Registry System | Furan, 2,2'-[dithiobis(methylene)]bis- (4437-20-1) |
| UNSPSC Code | 12352200 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| PPE | Eyeshields, Gloves | |||||||||
| Safety Statements | 24/25 | |||||||||
| RIDADR | UN 3334 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29321900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
Difurfuryldisulfide price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W314609 | 2,2′-(Dithiodimethylene)difuran ≥95%, FG | 4437-20-1 | 1 each | $58 | 2026-04-30 | Buy |
| Sigma-Aldrich | W314609 | 2,2′-(Dithiodimethylene)difuran ≥95%, FG | 4437-20-1 | 100g | $156 | 2026-04-30 | Buy |
| Sigma-Aldrich | W314609 | 2,2′-(Dithiodimethylene)difuran ≥95%, FG | 4437-20-1 | 250g | $299 | 2026-04-30 | Buy |
| Sigma-Aldrich | W314609 | 2,2′-(Dithiodimethylene)difuran ≥95%, FG | 4437-20-1 | 1kg | $689 | 2026-04-30 | Buy |
| Sigma-Aldrich | 264768 | Furfuryl disulfide 95% | 4437-20-1 | 1g | $44.2 | 2026-04-30 | Buy |
Difurfuryldisulfide Chemical Properties, Uses, Production
Chemical Properties
Pale yellowish oily liquid. Slightly soluble in water, soluble in alcohol and oils.
Occurrence
Reported found in beef (boiled, cooked) and coffee
Uses
Furfuryl disulfide has been used in the preparation of poly(disulfido-imide)s by Diels-Alder (DA) reaction with the various bismaleimides.
Definition
ChEBI: Bis(2-furanylmethyl) disulfide is a heteroarene.
Preparation
Difurfuryl disulfide is produced from Furfural and Hydrogen sulfide gas.
Taste threshold values
Taste characteristics at 20 ppm: roasted, sulfuraceous, alliaceous, green and meaty.
General Description
Difurfuryl disulfide is a sulfur-containing volatile compound mainly found in roasted coffee. It is also the main degradation product of furfuryl mercaptan under Fenton-type reaction conditions.
Synthesis
98-02-2
4437-20-1
The general procedure for the synthesis of difurfuryldisulfide from furfuryl(base)thiols was as follows: a non-homogeneous mixture of 4-chlorobenzenethiol (0.145 g, 1 mmol) with KBrO3 (0.167 g, 1 mmol), (NH4)6Mo7O24-4H2O (0.124 g, 10 mmol), and CH3CN/H2O (7:3, 5 mL) was mixed. The reaction mixture was stirred in a fume hood for 4 min under ambient atmosphere and at room temperature. The reaction progress was monitored by thin layer chromatography (TLC) using EtOAc/n-C6H14 (1:13) as eluent. Upon completion of the reaction, CH2Cl2 (20 mL) was added and the reaction mixture was filtered. The filtrate was washed sequentially with 5% NaOH solution and water and then dried with anhydrous MgSO4. Finally, the difurfuryldisulfide product of sufficient purity was obtained by evaporating the solvent.
References
[1] Bulletin of the Chemical Society of Japan, 1996, vol. 69, # 3, p. 685 - 691
[2] Synthesis, 2007, # 21, p. 3286 - 3289
[3] Journal of Chemical Research - Part S, 2002, # 11, p. 564 - 566
[4] Synthetic Communications, 2011, vol. 41, # 2, p. 170 - 176
[5] Journal of Organic Chemistry, 1995, vol. 60, # 11, p. 3266 - 3267
Difurfuryldisulfide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fujian Fine New Material Technology Co., Ltd. | 18173168888 | 24314994600@qq.com | China | 96 | 58 |
| Tianjin Zhongxin Chemtech Co., Ltd. | 022-66880623 | sales@tjzxchem.com | China | 612 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing Donghualituo Techonlogy Development Co.,Ltd. | 010-88425576 | sales@dhltchem.com | China | 793 | 59 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
View Latest Price from Difurfuryldisulfide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | Difurfuryldisulfide
4437-20-1
|
$20.00 | 1kg | 99% | 1000mt | Jinan Finer Chemical Co., Ltd | |
 |
2026-09-02 | Difurfuryldisulfide
4437-20-1
|
$3.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | Difurfuryldisulfide
4437-20-1
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- Difurfuryldisulfide
4437-20-1
- $20.00
- 99%
- Jinan Finer Chemical Co., Ltd
-
- Difurfuryldisulfide
4437-20-1
- $3.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- Difurfuryldisulfide
4437-20-1
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
