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ChemicalBook >> CAS DataBase List >>7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-

7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-

7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Structure
7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- structure
CAS No.
2459302-77-1
Chemical Name:
7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-
Synonyms
Tofacitinib N-Oxopropanenitrile;7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-;Tofacitinib N-Oxopropanenitrile. 7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-
CBNumber:
CB98376533
Molecular Formula:
C19H21N7O2
Molecular Weight:
379.42
MDL Number:
MOL File:
2459302-77-1.mol
MSDS File:
SDS
Last updated:2026-05-28 05:03:01
Request For Quotation

7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Properties

Boiling point 643.8±55.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
pka -2.61±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Chemical Properties, Uses, Production

Uses

Tofacitinib N-Oxopropanenitrile is an impurity of Tofacitinib(C781351); a Janus kinase inhibitor for treatment of rheumatoid arthritis.

7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Preparation Products And Raw materials

Raw materials

Preparation Products

7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Suppliers

Global Suppliers ( 10)
Supplier Tel Email Country ProdList Advantage
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9995 55
Tianjin shijia biomedical technology co., LTD 15022261580 tjshj1212@163.com China 2749 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-025-66113011 15955137747 cb5@aikonchem.com China 10354 58
Guangzhou Zhenlin Pharmaceutical Technology Co., Ltd 020-18102736 13622807357 Zark@zlstandards.com China 8296 58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 13165688766 3504943249@qq.com China 3000 58
Beijing Kemaiqi Medical Technology Co., LTD 15910349257 15910349257 245546570@qq.com China 1564 58
Changzhou Xianglong Pharmaceutical Technology Co., Ltd., 18915873328 18915873328 sales@xianglongpharm.com China 11049 58
Nanjing Yiming Pharmaceutical Technology Co., Ltd. 19850700912; 19850700912 13851286085@163.com China 979 58
Supplier Advantage
Shanghai Kewel Chemical Co., Ltd. 50
Hubei Yangxin Medical Technology Co., Ltd. 55
Tianjin shijia biomedical technology co., LTD 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 58
Guangzhou Zhenlin Pharmaceutical Technology Co., Ltd 58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 58
Beijing Kemaiqi Medical Technology Co., LTD 58
Changzhou Xianglong Pharmaceutical Technology Co., Ltd., 58
Nanjing Yiming Pharmaceutical Technology Co., Ltd. 58

2459302-77-1 (7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-) Related Search:

2-Pentenoic acid, 3-amino-2-cyano-5-[(3R,4R)-4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-5-oxo-, ethyl ester 2-Pentenoic acid, 3-amino-2-cyano-5-[(3R,4R)-4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-5-oxo-, butyl ester Tofacitinib
Tofacitinib N-Oxopropanenitrile Tofacitinib N-Oxopropanenitrile. 7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- 7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- 2459302-77-1