RO27-3225 TFA
- CAS No.
- 1373926-49-8
- Chemical Name:
- RO27-3225 TFA
- Synonyms
- RO27-3225 TFA
- CBNumber:
- CB98495339
- Molecular Formula:
- C41H53F3N12O8
- Molecular Weight:
- 898.95
- MDL Number:
- MOL File:
- 1373926-49-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
RO27-3225 TFA price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 41558 | RO27-3225 (trifluoroacetate salt) ≥98% | 1373926-49-8 | 1mg | $28 | 2026-04-30 | Buy |
| Cayman Chemical | 41558 | RO27-3225 (trifluoroacetate salt) ≥98% | 1373926-49-8 | 5mg | $131 | 2026-04-30 | Buy |
| Cayman Chemical | 41558 | RO27-3225 (trifluoroacetate salt) ≥98% | 1373926-49-8 | 10mg | $248 | 2026-04-30 | Buy |
| Cayman Chemical | 41558 | RO27-3225 (trifluoroacetate salt) ≥98% | 1373926-49-8 | 25mg | $550 | 2026-04-30 | Buy |
| ChemScene | CS-0115494 | RO27-3225 TFA 98.50% | 1373926-49-8 | 1mg | $54 | 2026-06-04 | Buy |
RO27-3225 TFA Chemical Properties,Uses,Production
Description
RO27-3225, also known as RO273225 is a melanocortin type 4 receptor agonist with EC50 = 1 nM. It may alleviate intestinal dysfuntion and brain damage. It has been investigated for an anti-obesity medication. Ro 27-3225 shows some activity at the MC1 receptor. Ro 27-3225 reverses hemorrhagic shock, reduces multiple organ damage, and improves survival.
Uses
RO27-3225 trifluoroacetate is a peptide agonist of melanocortin receptor 4 (MC4R) with neuroprotective and anti-inflammatory activity with an EC50 value of 1 nM, while 8 nM for MC1R. RO27-3225 trifluoroacetate reverses hemorrhagic shock, reduces brain edema, blood-brain barrier (BBB) permeability, and hippocampal IL-1β and TNF-α levels in a rat model of intra-abdominal hypertension induced by hemorrhagic shock and resuscitation[1][2].
IC 50
MC4R: 1 nM (EC50); MC1R: 8 nM (EC50)
References
[1] Liu D, et al. Melanocortin MC4 receptor agonists alleviate brain damage in abdominal compartment syndrome in the rat. Neuropeptides. 2015 Feb;49:55-61. DOI:10.1016/j.npep.2014.12.003
[2] Benoit SC, et al. A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences. J Neurosci. 2000 May 1;20(9):3442-8. DOI:10.1523/JNEUROSCI.20-09-03442.2000
RO27-3225 TFA Preparation Products And Raw materials
Raw materials
Preparation Products
RO27-3225 TFA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| Wuxi Helen Biotechnology Co., Ltd., | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 14072 | 58 |
| InvivoChem | 13549236410 | sales@invivochem.cn | China | 6745 | 58 |
| Nanjing Yuanpeptide Biotech Co.，Ltd. | 13357818155 | linhui@yuan-peptide.com | China | 2901 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
View Lastest Price from RO27-3225 TFA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | RO27-3225 TFA
1373926-49-8
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- RO27-3225 TFA
1373926-49-8
- $1520.00-2500.00
- TargetMol Chemicals Inc.
