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2-Amino-3-o-chlorobenzoyl-5-ethylthiophene

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Structure
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene structure
CAS No.
50508-60-6
Chemical Name:
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
Synonyms
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene;2-Amino-5-ethyl-3-(2-chlorobenzoyl)thiophene;Methanone,(2-aMino-5-ethyl-3-thienyl)(2-chlorophenyl)-;(2-AMino-5-ethylthiophen-3-yl)(2-chlorophenyl)Methanone
CBNumber:
CB9947146
Molecular Formula:
C13H12ClNOS
Molecular Weight:
265.76
MDL Number:
MFCD04107940
MOL File:
50508-60-6.mol
MSDS File:
SDS
Last updated:2026-05-28 05:21:03
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2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Properties

Boiling point 454.8±45.0 °C(Predicted)
Density 1.302
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): insol
form a crystalline solid
pka -1.81±0.10(Predicted)
InChI InChI=1S/C13H12ClNOS/c1-2-8-7-10(13(15)17-8)12(16)9-5-3-4-6-11(9)14/h3-7H,2,15H2,1H3
InChIKey RFCCZAHPNNJKKR-UHFFFAOYSA-N
SMILES C(C1C=C(CC)SC=1N)(C1=CC=CC=C1Cl)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 36070 2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene ≥98% 50508-60-6 1mg $57 2026-04-30 Buy
Cayman Chemical 36070 2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene ≥98% 50508-60-6 5mg $252 2026-04-30 Buy
TRC TRC-A603355-50MG 2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene 50508-60-6 50mg $65 2026-06-03 Buy
TRC TRC-A603355-250MG 2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene 50508-60-6 250mg $96 2026-06-03 Buy
TRC TRC-A603355-100MG 2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene 50508-60-6 100mg $78 2026-06-03 Buy
Product number Packaging Price Buy
36070 1mg $57 Buy
36070 5mg $252 Buy
TRC-A603355-50MG 50mg $65 Buy
TRC-A603355-250MG 250mg $96 Buy
TRC-A603355-100MG 100mg $78 Buy

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Chemical Properties, Uses, Production

Description

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene can be used as the raw material for the synthesis of Etizolam, which is an important sedative hypnotic and antidepressant drug. Its derivative, 2-amino-3-(p-chlorobenzoyl) thiophene scaffold has been widely employed as a pharmacophore for the identification of small molecules acting as allosteric modulators at the adenosine A1 receptor. 

References

Kai, Yong Mao, et al. "An Improved Synthesis of Etizolam." Journal of Southwest University of Science & Technology  (2014).
Romagnoli, R, et al. Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study..Longing for the end. Macmillan, 2015:185–204.

Chemical Properties

Yellow Solid

Uses

Used in the preparation of thienylamide derivatives as cholecystokinin inhibitors.

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Preparation Products And Raw materials

Raw materials

Preparation Products

2-Amino-3-o-chlorobenzoyl-5-ethylthiophene Suppliers

Global Suppliers ( 100)
Supplier Tel Email Country ProdList Advantage
Beijing Cooperate Pharmaceutical Co.,Ltd +86-010-60279497 +86-15646567669 sales01@cooperate-pharm.com China 135 58
Jiaxing Hengrui Biotechnology Co. LTD 0573-0573-82672231 13757365595 regen_chemical1@163.com China 4857 58
Shandong Hydrocarbon Bio-Chemical Co. LTD 13060081947 13060081947 1581910236@qq.com China 1592 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shanghai Famo Bio-chemical Technology Company Ltd. 021-36680027 15821745250 fengqiang@famobiotech.com China 494 56
Shanghai Huikai Chemical Technology Co., Ltd. 021-61995394 18916691159 chemicalsea@163.com China 1970 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai YuLue Chemical Co., Ltd. 021-60345187 13671753212 lzz841106@aliyun.com China 10244 55
Shanghai Synteam Biochem CO.,ltd +86-021-58380978 13482386415 info@systeambc.com China 897 50
Supplier Advantage
Beijing Cooperate Pharmaceutical Co.,Ltd 58
Jiaxing Hengrui Biotechnology Co. LTD 58
Shandong Hydrocarbon Bio-Chemical Co. LTD 58
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
Shanghai Famo Bio-chemical Technology Company Ltd. 56
Shanghai Huikai Chemical Technology Co., Ltd. 58
Bide Pharmatech Ltd. 60
Shanghai YuLue Chemical Co., Ltd. 55
Shanghai Synteam Biochem CO.,ltd 50

View Latest Price from 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene pictures 2019-07-06 2-Amino-3-o-chlorobenzoyl-5-ethylthiophene
50508-60-6
 $1.00 1kg 98% 100KG Career Henan Chemical Co

50508-60-6 (2-Amino-3-o-chlorobenzoyl-5-ethylthiophene ) Related Search:

p-Aminobenzamide glutamic acid Etizolam JP Luminol Benzoyl chloride, 4-amino- (9CI) Anthranilamide
Benzo[b]thiophene-6-carboxylic acid, 2-amino-3-(2-chlorobenzoyl)-4,5,6,7-tetrahydro-, methyl ester Benzo[b]thiophene-6-carboxylic acid, 2-amino-3-(2-chlorobenzoyl)-4,5,6,7-tetrahydro-, ethyl ester AKOS 221-03 AKOS 221-04 AKOS 92301
2-Amino-3-o-chlorobenzoyl-5-ethylthiophene

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2-Amino-3-o-chlorobenzoyl-5-ethylthiophene 2-Amino-5-ethyl-3-(2-chlorobenzoyl)thiophene Methanone,(2-aMino-5-ethyl-3-thienyl)(2-chlorophenyl)- (2-AMino-5-ethylthiophen-3-yl)(2-chlorophenyl)Methanone 50508-60-6 Thiophene heterocycles