6-Bromo-7-methylimidazo[1,2-a]pyridine
- CAS No.
- 116355-18-1
- Chemical Name:
- 6-Bromo-7-methylimidazo[1,2-a]pyridine
- Synonyms
- 6-broMo-7-MethylH-iMidazo[1;6-Bromo-7-methylimidazo[1,2-a]pyridine;Imidazo[1,2-a]pyridine, 6-bromo-7-methyl-;6-Bromo-7-methylimidazo[1,2-a]pyridine98%;6-Bromo-7-methylimidazo[1,2-a]pyridine 98%
- CBNumber:
- CB9957967
- Molecular Formula:
- C8H7BrN2
- Molecular Weight:
- 211.06
- MDL Number:
- MFCD09258769
- MOL File:
- 116355-18-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| Hazard Codes | Xi |
| Hazard Note | Irritant |
| HS Code | 2933599590 |
6-Bromo-7-methylimidazo[1,2-a]pyridine price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR3506 | 6-Bromo-7-methylimidazo[1,2-a]pyridine 98% | 116355-18-1 | 1g | $47 | 2026-06-04 | Buy |
| Apolloscientific | OR3506 | 6-Bromo-7-methylimidazo[1,2-a]pyridine 98% | 116355-18-1 | 5g | $142 | 2026-06-04 | Buy |
| Apolloscientific | OR3506 | 6-Bromo-7-methylimidazo[1,2-a]pyridine 98% | 116355-18-1 | 25g | $538 | 2026-06-04 | Buy |
| Synthonix | B48320 | 6-Bromo-7-methylimidazo[1,2-a]pyridine 95+% | 116355-18-1 | 250mg | $25 | 2026-05-06 | Buy |
| Synthonix | B48320 | 6-Bromo-7-methylimidazo[1,2-a]pyridine 95+% | 116355-18-1 | 1g | $40 | 2026-05-06 | Buy |
6-Bromo-7-methylimidazo[1,2-a]pyridine Chemical Properties,Uses,Production
Uses
6-Bromo-7-methylimidazo[1,2-a]pyridine is used as an intermediate in pharmaceuticals and synthetic materials.
Synthesis
107-20-0
98198-48-2
116355-18-1
A solution of 5-bromo-4-methylpyridin-2-amine (8 g, 42.78 mmol) and chloroacetaldehyde (~50% wt aqueous solution, 27.52 mL, 214 mmol) in ethanol (50 mL) was heated to 100°C under nitrogen protection and reacted for 16 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in ethyl acetate (100 mL) and the organic phase was washed sequentially with saturated sodium bicarbonate solution (2 x 50 mL), water (2 x 50 mL) and saturated saline (2 x 100 mL). The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 6-bromo-7-methylimidazo[1,2-a]pyridine (8.5 g, 94% yield) as a brown solid. The product was characterized by 1H NMR (400 MHz, DMSO-d6) and LC-MS: 1H NMR δ 8.93 (s, 1H), 7.85 (s, 1H), 7.57 (d, J = 7.56 Hz, 2H), 2.38 (s, 3H); LC-MS (95%) m/z 211 [C8H7BrN2 + H]+.
References
[1] Patent: WO2013/147711, 2013, A1. Location in patent: Page/Page column 207
[2] Patent: US2014/371199, 2014, A1. Location in patent: Paragraph 0729
[3] Patent: WO2010/108074, 2010, A2. Location in patent: Page/Page column 68-69
6-Bromo-7-methylimidazo[1,2-a]pyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Amico Chemicals Co. LTD | 微信 18019252918 18019252918 | 1454668768@qq.com | China | 14933 | 58 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |





