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6-Bromo-7-methylimidazo[1,2-a]pyridine

CAS No.
116355-18-1
Chemical Name:
6-Bromo-7-methylimidazo[1,2-a]pyridine
Synonyms
6-broMo-7-MethylH-iMidazo[1;6-Bromo-7-methylimidazo[1,2-a]pyridine;Imidazo[1,2-a]pyridine, 6-bromo-7-methyl-;6-Bromo-7-methylimidazo[1,2-a]pyridine98%;6-Bromo-7-methylimidazo[1,2-a]pyridine 98%
CBNumber:
CB9957967
Molecular Formula:
C8H7BrN2
Molecular Weight:
211.06
MDL Number:
MFCD09258769
MOL File:
116355-18-1.mol
MSDS File:
SDS
Last updated:2026-05-28 05:23:16

6-Bromo-7-methylimidazo[1,2-a]pyridine Properties

storage temp. 2-8°C
form powder
color Light beige
InChI InChI=1S/C8H7BrN2/c1-6-4-8-10-2-3-11(8)5-7(6)9/h2-5H,1H3
InChIKey TYDYYXQQGZNATK-UHFFFAOYSA-N
SMILES C12=NC=CN1C=C(Br)C(C)=C2

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
Hazard Note  Irritant
HS Code  2933599590

6-Bromo-7-methylimidazo[1,2-a]pyridine price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR3506 6-Bromo-7-methylimidazo[1,2-a]pyridine 98% 116355-18-1 1g $47 2026-06-04 Buy
Apolloscientific OR3506 6-Bromo-7-methylimidazo[1,2-a]pyridine 98% 116355-18-1 5g $142 2026-06-04 Buy
Apolloscientific OR3506 6-Bromo-7-methylimidazo[1,2-a]pyridine 98% 116355-18-1 25g $538 2026-06-04 Buy
Synthonix B48320 6-Bromo-7-methylimidazo[1,2-a]pyridine 95+% 116355-18-1 250mg $25 2026-05-06 Buy
Synthonix B48320 6-Bromo-7-methylimidazo[1,2-a]pyridine 95+% 116355-18-1 1g $40 2026-05-06 Buy
Product number Packaging Price Buy
OR3506 1g $47 Buy
OR3506 5g $142 Buy
OR3506 25g $538 Buy
B48320 250mg $25 Buy
B48320 1g $40 Buy

6-Bromo-7-methylimidazo[1,2-a]pyridine Chemical Properties,Uses,Production

Uses

6-Bromo-7-methylimidazo[1,2-a]pyridine is used as an intermediate in pharmaceuticals and synthetic materials.

Synthesis

Chloroacetaldehyde

107-20-0

2-Amino-5-bromo-4-methylpyridine

98198-48-2

6-Bromo-7-methylimidazo[1,2-a]pyridine

116355-18-1

A solution of 5-bromo-4-methylpyridin-2-amine (8 g, 42.78 mmol) and chloroacetaldehyde (~50% wt aqueous solution, 27.52 mL, 214 mmol) in ethanol (50 mL) was heated to 100°C under nitrogen protection and reacted for 16 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in ethyl acetate (100 mL) and the organic phase was washed sequentially with saturated sodium bicarbonate solution (2 x 50 mL), water (2 x 50 mL) and saturated saline (2 x 100 mL). The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 6-bromo-7-methylimidazo[1,2-a]pyridine (8.5 g, 94% yield) as a brown solid. The product was characterized by 1H NMR (400 MHz, DMSO-d6) and LC-MS: 1H NMR δ 8.93 (s, 1H), 7.85 (s, 1H), 7.57 (d, J = 7.56 Hz, 2H), 2.38 (s, 3H); LC-MS (95%) m/z 211 [C8H7BrN2 + H]+.

References

[1] Patent: WO2013/147711, 2013, A1. Location in patent: Page/Page column 207
[2] Patent: US2014/371199, 2014, A1. Location in patent: Paragraph 0729
[3] Patent: WO2010/108074, 2010, A2. Location in patent: Page/Page column 68-69

6-Bromo-7-methylimidazo[1,2-a]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 72)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Amico Chemicals Co. LTD 微信 18019252918 18019252918 1454668768@qq.com China 14933 58
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60

6-Bromo-7-methylimidazo[1,2-a]pyridine Spectrum

6-broMo-7-MethylH-iMidazo[1 6-Bromo-7-methylimidazo[1,2-a]pyridine 6-Bromo-7-methylimidazo[1,2-a]pyridine 98% 6-Bromo-7-methylimidazo[1,2-a]pyridine98% Imidazo[1,2-a]pyridine, 6-bromo-7-methyl- 116355-18-1 blocks Bromides Imidazoles Pyridines