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2-amino-N,N-dimethylacetamide

2-amino-N,N-dimethylacetamide Structure
2-amino-N,N-dimethylacetamide structure
CAS No.
1857-19-8
Chemical Name:
2-amino-N,N-dimethylacetamide
Synonyms
A80236;Glycine dimethylamide, 97%;N~1~,N~1~-dimethylglycinamide;N,N-Dimethyl-2-aminoacetamide;2-Amino-N,N-dimethylacetamide;1,1-diMethylurea hydrochloride;AcetaMide, 2-aMino-N,N-diMethyl;2-diazenyl-N,N-dimethylacetamide;2-aMino-N,N-diMethylacetaMide hcl;N~1~,N~1~-dimethylglycinamide 1HCl
CBNumber:
CB9970898
Molecular Formula:
C4H10N2O
Molecular Weight:
102.14
MDL Number:
MFCD06655264
MOL File:
1857-19-8.mol
MSDS File:
SDS
Last updated:2026-05-28 05:27:35
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2-amino-N,N-dimethylacetamide Properties

Boiling point 60 °C(Press: 0.8 Torr)
Density 0.995±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 8.46±0.10(Predicted)
form liquid
color Colorless
Sensitive Air Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314-H318
Precautionary statements  P280-P305+P351+P338-P309-P310
HazardClass  8
HS Code  2922498590
NFPA 704
1
3 0

2-amino-N,N-dimethylacetamide price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR952034 2-Amino-N,N-dimethylacetamide >99% 1857-19-8 1g $54 2026-06-04 Buy
Apolloscientific OR952034 2-Amino-N,N-dimethylacetamide >99% 1857-19-8 5g $198 2026-06-04 Buy
Apolloscientific OR952034 2-Amino-N,N-dimethylacetamide >99% 1857-19-8 25g $772 2026-06-04 Buy
Matrix Scientific 132232 2-Amino-N,N-dimethylacetamide 1857-19-8 1.00g $72 2026-05-18 Buy
Matrix Scientific 132232 2-Amino-N,N-dimethylacetamide 1857-19-8 5.00g $278 2026-05-18 Buy
Product number Packaging Price Buy
OR952034 1g $54 Buy
OR952034 5g $198 Buy
OR952034 25g $772 Buy
132232 1.00g $72 Buy
132232 5.00g $278 Buy

2-amino-N,N-dimethylacetamide Chemical Properties,Uses,Production

Uses

Glycine dimethylamide is used as pharmaceutical intermediate.

Synthesis

Benzyl N-[(diMethylcarbaMoyl)Methyl]carbaMate

167303-60-8

2-amino-N,N-dimethylacetamide

1857-19-8

GENERAL STEPS: This procedure was used for the synthesis of 2-amino-N,N-dimethylacetamide (compound 11a). To a solution of benzyl (2-(dimethylamino)-2-oxoethyl)carbamate (compound 10a, 170 mg, 0.77 mmol) in methanol (10 mL) was added 10% Pd/C catalyst. The reaction was hydrogenated at room temperature and atmospheric pressure for 3 hours. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the filtrate was concentrated and dried to give 2-amino-N,N-dimethylacetamide as an oily product. The reaction process was monitored by TLC. Due to product stability considerations, the resulting amine was used directly in the subsequent reaction. The yield was 97%.

References

[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 3, p. 1285 - 1297
[2] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 16, p. 2715 - 2718
[3] Chemical Communications, 2016, vol. 52, # 43, p. 7043 - 7046

2-amino-N,N-dimethylacetamide synthesis

167303-60-8
1857-19-8
Synthesis of 2-amino-N,N-dimethylacetamide from Benzyl N-[(diMethylcarbaMoyl)Methyl]carbaMate

2-amino-N,N-dimethylacetamide Preparation Products And Raw materials

Raw materials

2,5-Oxazolidinedione Benzyl N-[(diMethylcarbaMoyl)Methyl]carbaMate tert-butyl N-[2-(dimethylamino)-2-oxoethyl]carbamate Dimethylamine N-Carbobenzyloxyglycine
Methanol Activated carbon Palladium Hydrogen

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Preparation Products

2-amino-N,N-dimethylacetamide Suppliers

Global( 97)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Chembon Pharmaceutical Co., Ltd. 028-84252981 18583719936 sales@chembon.com.cn China 854 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Nanjing Vital Chemical Co., Ltd. Please Send Email 18652950785 chemweiao@163.com China 4368 65
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1997 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
Energy Chemical 61
Chembon Pharmaceutical Co., Ltd. 64
Shandong Xiya Chemical Co., Ltd 57
Syntechem Co.,Ltd 57
Nanjing Vital Chemical Co., Ltd. 65
Shanghai Sphchem Co., Ltd. 55
Chengdu Forest Science and Technology Development Co., Ltd. 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55

View Lastest Price from 2-amino-N,N-dimethylacetamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-amino-N,N-dimethylacetamide pictures 2026-08-20 2-amino-N,N-dimethylacetamide
1857-19-8
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-amino-N,N-dimethylacetamide pictures 2020-01-09 2-amino-N,N-dimethylacetamide
1857-19-8
 $1.00 1ASSAYS 85.0-99.8% 20tons Career Henan Chemical Co

2-amino-N,N-dimethylacetamide Spectrum

2-amino-N,N-dimethylacetamide(1857-19-8)1HNMR

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N,N-Dimethyl-2-aminoacetamide 2-diazenyl-N,N-dimethylacetamide 2-aMino-N,N-diMethylacetaMide hcl AcetaMide, 2-aMino-N,N-diMethyl 1,1-diMethylurea hydrochloride 2-Amino-N,N-dimethylacetamide Glycine dimethylamide, 97% A80236 N~1~,N~1~-dimethylglycinamide(SALTDATA: HCl) N~1~,N~1~-dimethylglycinamide 1HCl N~1~,N~1~-dimethylglycinamide 2-amino-N,N-dimethylacetamide ISO 9001：2015 REACH 1857-19-8 NH2CH2CONCH32